KEGG   Mus musculus (house mouse): 12649
Entry
12649             CDS       T01002                                 
Symbol
Chek1, Chk1, rad27
Name
(RefSeq) checkpoint kinase 1
  KO
K02216  serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04110  Cell cycle
mmu04115  p53 signaling pathway
mmu04218  Cellular senescence
mmu05166  Human T-cell leukemia virus 1 infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    12649 (Chek1)
   04115 p53 signaling pathway
    12649 (Chek1)
   04218 Cellular senescence
    12649 (Chek1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    12649 (Chek1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    12649 (Chek1)
   05170 Human immunodeficiency virus 1 infection
    12649 (Chek1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    12649 (Chek1)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mmu03400]
    12649 (Chek1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     12649 (Chek1)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   12649 (Chek1)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    12649 (Chek1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Kdo
Other DBs
NCBI-GeneID: 12649
NCBI-ProteinID: NP_031717
MGI: 1202065
Ensembl: ENSMUSG00000032113
UniProt: O35280
Position
9:complement(36619935..36637897)
AA seq 476 aa
MAVPFVEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINK
MLSHENVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVY
LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLK
RKEFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
LLHKILVETPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDF
SPVNNGSSEETVKFSSSQPEPRTGLSLWDTGPSNVDKLVQGISFSQPTCPEHMLVNSQLL
GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETFEKLGYQWKKSCMNQVTVSTTDRR
NNKLIFKINLVEMDEKILVDFRLSKGDGLEFKRHFLKIKGKLSDVVSSQKVWFPVT
NT seq 1431 nt   +upstreamnt  +downstreamnt
atggcagtgccttttgtggaagactgggatttggtgcaaactttgggagaaggtgcctat
ggagaagttcaacttgctgtgaatagaataactgaagaagctgttgcagtgaaaattgta
gacatgaagcgggccatagactgtccagaaaatattaagaaagagatctgcatcaataaa
atgttaagccacgagaatgtagtgaaattctatggccacaggagggaaggccatatccag
tatctgtttctggagtactgtagtggaggagaactttttgatagaattgagccagacata
gggatgcctgaacaagatgctcagaggttcttccaccaactcatggcaggggtggtttat
cttcatggaattggaataactcacagggatattaaaccagaaaacctcctcttggatgaa
agggataacctcaaaatctctgactttggcttggcaacggtatttcggcataataatcgt
gaacgcttactgaacaagatgtgtgggactttaccttatgttgctccggagcttctaaag
agaaaagaatttcatgcagaaccagttgatgtttggtcctgtggaatagtacttactgca
atgttggctggagaattgccgtgggaccagcccagtgatagctgtcaggaatattctgat
tggaaagaaaaaaaaacctatctcaatccttggaaaaaaattgattctgctcctctggct
ttgcttcataaaattctagttgagactccatcagcaaggatcaccatcccagacattaag
aaagatagatggtacaacaaaccacttaacagaggagcaaagaggccacgcgccacatca
ggtggtatgtcagagtcttctagtggattctctaagcacattcattccaatttggacttt
tctccagtaaataatggttccagtgaagaaaccgtgaagttctctagttcccagccagag
ccgagaacagggctttccttgtgggacactggtccctcgaacgtggacaaactggttcag
ggcatcagtttttcccagcctacgtgtcctgagcatatgcttgtaaacagtcagttactc
ggtacccctggatcttcacagaacccctggcagcgcttggtcaaaaggatgacacgattc
tttactaaattggatgcggacaaatcttaccaatgcctgaaagagaccttcgagaagttg
ggctatcagtggaagaagagttgtatgaatcaggttactgtatcaacaactgatagaaga
aacaataagttgattttcaaaataaatttggtagaaatggatgagaagatactggttgac
ttccgactttctaagggtgatggattagagttcaagagacacttcctgaagattaaaggg
aagctcagcgatgttgtgagcagccagaaggtttggtttcctgttacatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (25)   
   RefSeq(nuc) (5)   
   GenBank (10)   
   EMBL (10)   
Protein domain (6)   
   Pfam (6)   
All databases (62)   

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