KEGG   Mus musculus (house mouse): 12669
Entry
12669             CDS       T01002                                 
Symbol
Chrm1, Chrm-1, M1, M1R
Name
(RefSeq) cholinergic receptor, muscarinic 1, CNS
  KO
K04129  muscarinic acetylcholine receptor M1
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04020  Calcium signaling pathway
mmu04024  cAMP signaling pathway
mmu04080  Neuroactive ligand-receptor interaction
mmu04151  PI3K-Akt signaling pathway
mmu04725  Cholinergic synapse
mmu04810  Regulation of actin cytoskeleton
mmu05010  Alzheimer disease
mmu05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    12669 (Chrm1)
   04024 cAMP signaling pathway
    12669 (Chrm1)
   04151 PI3K-Akt signaling pathway
    12669 (Chrm1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    12669 (Chrm1)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    12669 (Chrm1)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    12669 (Chrm1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    12669 (Chrm1)
   05022 Pathways of neurodegeneration - multiple diseases
    12669 (Chrm1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:mmu04030]
    12669 (Chrm1)
G protein-coupled receptors [BR:mmu04030]
 Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    12669 (Chrm1)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srbc 7tm_4 7TM_GPCR_Srx
Other DBs
NCBI-GeneID: 12669
NCBI-ProteinID: NP_001106167
MGI: 88396
Ensembl: ENSMUSG00000032773
UniProt: P12657
Position
19:8641369..8660970
AA seq 460 aa
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgaacacctcagtgccccctgctgtcagtcccaacatcaccgtcttggcaccaggaaag
ggtccctggcaagtggcattcatcgggatcaccacaggcctcctgtctctggctacagtg
acaggcaacctgctggtgctcatctccttcaaggtcaacacagagctcaagacagtcaac
aactacttcctgctgagcctggcctgtgctgatctcatcattggcactttctccatgaac
ctctataccacatacctgctcatgggccactgggctctgggcacactggcctgtgacctc
tggctggccctggactatgtggccagcaacgcctctgtcatgaatcttctgctcatcagc
tttgaccgttacttctcagtgacccgacccctgagctaccgagccaagcgcactccccgc
agggcagctctgatgattggcctcgcgtggttggtttccttcgttctctgggccccagcc
atcctcttctggcaatacctagttggggagcggacagtgctggctgggcagtgctacatc
cagttcctctcccaacccatcatcacttttggcacagccatggccgccttctacctccct
gtcacagtcatgtgtacgctgtactggcgcatctaccgggagacagaaaaccgagcccgg
gagctagcagccctacagggctctgagacaccaggcaaaggtggtggcagcagcagcagc
tcagagaggtcacagccaggagctgaaggctcacccgagtcacctccaggccgctgctgt
cgctgttgccgggcacccagacttctgcaggcctacagctggaaagaagaagaggaagag
gatgaaggctccatggagtccctcacatcctctgaaggtgaggagcctggctcagaagtg
gtgatcaagatgcctatggtagatcctgaggcacaggcacccaccaagcagcctcccaaa
agctccccaaatacagtcaagaggcccaccaagaaaggccgagaccgaggcggcaaaggc
caaaaaccccgagggaaggaacaactggccaagagaaagaccttctcactggtcaaggag
aagaaggcagctcggaccctgagtgccatcctgctggccttcatcctcacctggacacca
tataacatcatggtgctggtgtctacattctgcaaggactgtgttccagaaaccctatgg
gagctgggctactggctttgctacgtcaacagcactgtcaaccccatgtgctacgcactc
tgcaacaaagccttccgggacactttccgcctgctgttgctctgccgctgggacaagcgg
cgctggcgcaaaatccccaagcgccctggctctgtgcaccgcaccccctcccgccaatgc
taa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (16)   
   RefSeq(nuc) (2)   
   GenBank (7)   
   EMBL (7)   
Protein domain (5)   
   Pfam (5)   
All databases (54)   

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