KEGG   Mus musculus (house mouse): 12846
Entry
12846             CDS       T01002                                 
Symbol
Comt, Comt1, D16Wsu103e, D330014B15Rik
Name
(RefSeq) catechol-O-methyltransferase
  KO
K00545  catechol O-methyltransferase [EC:2.1.1.6]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00140  Steroid hormone biosynthesis
mmu00350  Tyrosine metabolism
mmu01100  Metabolic pathways
mmu04728  Dopaminergic synapse
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    12846 (Comt)
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    12846 (Comt)
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    12846 (Comt)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:mmu03037]
    12846 (Comt)
   04147 Exosome [BR:mmu04147]
    12846 (Comt)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.6  catechol O-methyltransferase
     12846 (Comt)
Cilium and associated proteins [BR:mmu03037]
 Other cilia and associated proteins
  Stereociliary proteins
   12846 (Comt)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   12846 (Comt)
SSDB
Motif
Pfam: Methyltransf_3 Methyltransf_24 RMNT_CmcI Methyltransf_25 Nitroreductase Methyltransf_31
Other DBs
NCBI-GeneID: 12846
NCBI-ProteinID: NP_001104532
MGI: 88470
Ensembl: ENSMUSG00000000326
UniProt: O88587
Structure
Position
16:complement(18225632..18247006)
AA seq 265 aa
MLLAAVSLGLLLLAFLLLLRHLGWGLVAIGWFEFVQQPVHNLLMGGTKEQRILRHVQQHA
KPGDPQSVLEAIDTYCSEKEWAMNVGDAKGQIMDAVIREYRPSLVLELGAYCGYSAVRMA
RLLPPGARLLTMEINPDYAAITQQMLDFAGLQDKVSILIGASQDLIPQLKKKYDVDTLDM
VFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSY
LEYMKVVDGLEKAVYQGPGSSPVKS
NT seq 798 nt   +upstreamnt  +downstreamnt
atgctgttggctgctgtctcattgggtctcctgttgctggccttcctcctgctcctgcga
cacctaggctggggcttggtggctattggttggtttgagttcgtgcagcagccggtccac
aacctgctcatgggtggcacaaaggagcagcgcatcctgcgccatgtgcagcaacacgca
aagcctggagacccccagagcgtcctggaggccattgatacctactgctcagagaaggag
tgggccatgaacgtgggtgacgcaaaaggccaaatcatggatgcagtgattcgggagtac
aggccctcgctggtgctggagctaggagcttattgtggctactcagccgtgcgaatggcc
cgcctgctgccacctggagccaggcttctcaccatggagattaaccctgactacgctgcc
atcacccagcaaatgctggacttcgcaggcctacaggacaaagtttccatcctcatcggg
gcatcccaggaccttatcccccagctgaagaagaagtacgatgtggacacattagacatg
gtctttcttgaccactggaaagaccgctaccttccagacacacttctcctggaggaatgt
ggcctgctgcgcaaggggacggtgctcctagctgacaatgtcattgtcccgggaacccct
gacttcctggcgtatgtgagggggagcagcagcttcgagtgcacacactacagctcatac
ctggagtacatgaaagtggtggacggcttggagaaggcagtctaccagggtccaggcagc
agccccgtgaagtcctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (9)   
   KEGG ENZYME (1)   
   KEGG REACTION (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (96)   

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