KEGG   Mus musculus (house mouse): 13030
Entry
13030             CDS       T01002                                 
Symbol
Ctsb, CB
Name
(RefSeq) cathepsin B
  KO
K01363  cathepsin B [EC:3.4.22.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04140  Autophagy - animal
mmu04142  Lysosome
mmu04210  Apoptosis
mmu04612  Antigen processing and presentation
mmu04621  NOD-like receptor signaling pathway
mmu04924  Renin secretion
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    13030 (Ctsb)
   04140 Autophagy - animal
    13030 (Ctsb)
  09143 Cell growth and death
   04210 Apoptosis
    13030 (Ctsb)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    13030 (Ctsb)
   04612 Antigen processing and presentation
    13030 (Ctsb)
  09152 Endocrine system
   04924 Renin secretion
    13030 (Ctsb)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    13030 (Ctsb)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    13030 (Ctsb)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    13030 (Ctsb)
   00536 Glycosaminoglycan binding proteins [BR:mmu00536]
    13030 (Ctsb)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.1  cathepsin B
     13030 (Ctsb)
Peptidases and inhibitors [BR:mmu01002]
 Cysteine peptidases
  Family C1: papain family
   13030 (Ctsb)
Chaperones and folding catalysts [BR:mmu03110]
 Intramolecular chaperones
  Papain family
   13030 (Ctsb)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of microglial cells
   13030 (Ctsb)
Glycosaminoglycan binding proteins [BR:mmu00536]
 Heparan sulfate / Heparin
  Others
   13030 (Ctsb)
SSDB
Motif
Pfam: Peptidase_C1 Propeptide_C1
Other DBs
NCBI-GeneID: 13030
NCBI-ProteinID: NP_031824
MGI: 88561
Ensembl: ENSMUSG00000021939
UniProt: P10605
Position
14:63359911..63383372
AA seq 339 aa
MWWSLILLSCLLALTSAHDKPSFHPLSDDLINYINKQNTTWQAGRNFYNVDISYLKKLCG
TVLGGPKLPGRVAFGEDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDR
TCIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCL
PYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIM
AEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSW
NLDWGDNGFFKILRGENHCGIESEIVAGIPRTDQYWGRF
NT seq 1020 nt   +upstreamnt  +downstreamnt
atgtggtggtccttgatccttctttcttgcctgctggcactgaccagtgcccatgacaag
ccttccttccacccgctgtcggatgacctgattaactatatcaacaaacagaatacaaca
tggcaggctggacgcaacttctacaatgttgacataagctatctgaagaagctgtgtggc
actgtcctgggtggacccaaactgccaggaagggttgcgttcggtgaggacatagatcta
cctgaaacctttgatgcacgggaacaatggtccaactgcccgaccattggacagattaga
gaccagggctcctgcggctcttgttgggcatttggggcagtggaagccatttctgaccga
acctgcattcacaccaatggccgagtcaacgtggaggtgtctgctgaagacctgcttact
tgctgtggtatccagtgtggggacggctgtaatggtggctatccctctggagcatggagc
ttctggacaaaaaaaggcctggtttcaggtggagtctacaattctcatgtaggctgctta
ccatacaccatccctccctgcgagcaccatgtcaatggctcccgtcccccatgcactgga
gaaggagatactcccaggtgcaacaagagctgtgaagctggctactccccatcctacaaa
gaggataagcactttgggtacacttcctacagcgtgtctaacagtgtgaaggagatcatg
gcagaaatctacaaaaatggcccagtggagggtgccttcactgtgttttctgacttcttg
acttacaaatcaggagtatacaagcatgaagccggtgatatgatgggtggccacgccatc
cgcatcctgggctggggagtagagaatggagttccctactggctggcagccaactcttgg
aaccttgactggggtgataatggcttctttaaaatcctcagaggagagaaccactgtggc
attgaatcagaaattgtggctggaatcccacgcactgaccagtactggggaagattctaa

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (144)   
   RefSeq(nuc) (2)   
   GenBank (71)   
   EMBL (71)   
Protein domain (2)   
   Pfam (2)   
All databases (197)   

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