KEGG   Mus musculus (house mouse): 13116
Entry
13116             CDS       T01002                                 
Symbol
Cyp46a1, CH24H, Cyp46
Name
(RefSeq) cytochrome P450, family 46, subfamily a, polypeptide 1
  KO
K07440  cholesterol 24-hydroxylase [EC:1.14.14.25]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00120  Primary bile acid biosynthesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    13116 (Cyp46a1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mmu00199]
    13116 (Cyp46a1)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.25  cholesterol 24-hydroxylase
     13116 (Cyp46a1)
Cytochrome P450 [BR:mmu00199]
 Cytochrome P450, animal type
  CYP46 family
   13116 (Cyp46a1)
SSDB
Motif
Pfam: p450 Peptidase_M1 Rab5-bind
Other DBs
NCBI-GeneID: 13116
NCBI-ProteinID: NP_034140
MGI: 1341877
Ensembl: ENSMUSG00000021259
UniProt: Q9WVK8 Q3US73
Position
12:108300568..108328497
AA seq 500 aa
MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWKKDEDCGRVL
QDVFLDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERL
FGQGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSM
QDMLTCATIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPGKRKQL
REIRESIRLLRQVGKDWVQRRREALKRGEDMPADILTQILKAEEGAQDDEVLLDNFVTFF
IAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKES
LRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGA
PKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKPLD
PVLCTLRPRGWQPAPPPPPC
NT seq 1503 nt   +upstreamnt  +downstreamnt
atgagccccgggctgctgctgctcggcagcgccgtcctgctcgccttcggcctctgctgc
accttcgtgcatcgcgctcgcagccgctatgagcacatccccgggccgccgcggcccagc
ttccttcttggacatctcccctacttttggaaaaaggacgaagattgtggccgtgtgctc
caagatgtgtttctggattgggctaagaagtatggtcctgttgtaagagtcaatgtcttc
tacaagacctcagtcattgtcacgagtccggagtcagtcaagaagttcctgatgtccacc
aagtacaacaaggactccaagatgtaccgcgcgcttcagactgtgtttggggagagactg
tttggccagggcttggtgtctgaatgtgactatgggcgctggtacaagcagaggaaagtc
atggacttggccttcagccgcagctccttggtcagcctgatggagacgttcaacgagaag
gcggagcagctggtggaaatcctagaagctaaggcagatggacagacacccgtgtccatg
caggacatgctgacctgtgccaccatcgacatcctggccaaggcagcttttgggatggag
accagtatgttactgggtgcccagaaaccgctgtcccaggcagtgaaggtcatgctggag
ggcatcagtgcatcccgtaacaccctggcaaagttcatgccagggaagagaaagcagctt
cgggagatccgcgagagcatccgtctgctgcgccaggtggggaaggattgggtgcagcgc
cgccgcgaagccctgaagaggggcgaggacatgccggctgacatcctcacgcagatcctc
aaagctgaagagggagctcaggacgatgaggttctgctggacaactttgtcaccttcttc
attgcgggtcatgagacttctgccaaccatctggcattcacagtgatggagttgtctcgc
cagccagagattgtggcaaggctgcaggccgaggtggatgaggttgtcggttccaagagg
cacctggactacgaggatctggggagactgcagtatctgtcgcaggtcctcaaagagtct
ctgaggctgtacccgccagcgtggggcacctttcgcctgctggaggaggagaccttgatt
gatggggtcagagtccctggcaatactcctctcctgttcagcacctacgtcatggggaga
atggacacctactttgaagacccattgactttcaaccctgaccgcttcggccctggagcg
cccaagccacggttcacttactttcccttttccctgggccaccggtcctgcatcggccaa
cagtttgctcagatggaggtgaaagttgtcatggccaagctgcttcagaggatcgagttc
cggctagtgcctgggcagcgctttgggctgcaagagcaggctacgctcaagccattggac
cccgtgctgtgcaccctgaggccccggggctggcagcctgcacccccacccccaccctgc
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (3)   
   Pfam (3)   
All databases (42)   

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