KEGG   Mus musculus (house mouse): 13122
Entry
13122             CDS       T01002                                 
Symbol
Cyp7a1, CYPVII, CYPVIIc
Name
(RefSeq) cytochrome P450, family 7, subfamily a, polypeptide 1
  KO
K00489  cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00120  Primary bile acid biosynthesis
mmu00140  Steroid hormone biosynthesis
mmu01100  Metabolic pathways
mmu03320  PPAR signaling pathway
mmu04976  Bile secretion
mmu04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    13122 (Cyp7a1)
   00140 Steroid hormone biosynthesis
    13122 (Cyp7a1)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    13122 (Cyp7a1)
  09154 Digestive system
   04976 Bile secretion
    13122 (Cyp7a1)
   04979 Cholesterol metabolism
    13122 (Cyp7a1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mmu00199]
    13122 (Cyp7a1)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.23  cholesterol 7alpha-monooxygenase
     13122 (Cyp7a1)
Cytochrome P450 [BR:mmu00199]
 Cytochrome P450, animal type
  CYP7 family
   13122 (Cyp7a1)
SSDB
Motif
Pfam: p450 DUF5790 DUF2523 DUF1072
Other DBs
NCBI-GeneID: 13122
NCBI-ProteinID: NP_031850
MGI: 106091
Ensembl: ENSMUSG00000028240
UniProt: Q64505
Position
4:complement(6265612..6275632)
AA seq 503 aa
MMSISLIWGIAVVVSCCIWFIIGIRRRKVGEPPLDNGLIPYLGCALKFGSNPLEFLRAKQ
RKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPSDGN
TTENINKTFNKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSAVWVTEGMYAFCYRVMF
EAGYLTLFGKDISKTDSQRAFIQNNLDSFKQFDQVFPALVAGVPIHLFKTAHKARERLAE
SLKHKNLYMRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLVILWASQANTIPATFWSLFQ
MIRSPEAMKAASEEVNGALQSAGQELSSGGNAIYLDQEQLNNLPVLDSIIKEALRLSSAS
LNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAK
TTFYRNGNKLKYFYMPFGSGATICPGRLFAVQEIKQFLILMLSYFELELVESHTKCPPLD
QSRAGLGILPPLNDIEFKYKLKH
NT seq 1512 nt   +upstreamnt  +downstreamnt
atgatgagcatttctttgatctgggggattgctgtggtagtgagctgttgcatatggttt
atcattggaataaggagaaggaaagtaggtgaacctcctttggacaacgggttgattcca
tacctgggctgtgctctgaagttcggatccaatcctcttgaattcctaagagcaaagcaa
aggaaacatggccatgtttttacctgcaaactgatggggaaatatgtccacttcatcaca
aactccctgtcataccacaaagtcttatgtcacggaaaatattttgactggaaaaaattt
cattacactacttctgcgaaggcatttggacacagaagcatagacccaagtgatggaaat
accacggaaaacataaacaagacttttaacaaaaccctccagggagatgctctgtgttca
ctctctgaagccatgatgcaaaacctccaatctgtcatgagacctccgggccttcctaaa
tcaaagagcgctgtctgggtcacggaagggatgtatgccttctgctaccgagtgatgttt
gaagccggatatctaacgctgtttggcaaagatatttcaaagacagactcacaaagagca
tttattcaaaacaaccttgacagcttcaaacaatttgaccaagtatttccggcactagtg
gcgggcgtccctattcacttgttcaagaccgcacataaagcccgggaaaggctggctgag
agcttgaagcacaagaacctgtacatgagggaccaggtctctgaactgatccgtctacgc
atgtttctcaacgatacactctccacctttgatgacatggagaaggctaagacgcacctc
gtgatcctctgggcatctcaagcaaacaccattcctgcaaccttctggagcttatttcaa
atgatcaggagccctgaagcaatgaaagcagcctctgaagaagtgaatggagcattacag
agtgctggccaagagctcagctctggagggaatgccatttacttggatcaagagcaacta
aacaacctgccagtactagatagcatcatcaaggaggctctgcggctctccagtgcatcc
ttgaatatccggacagctaaggaggacttcactctacaccttgaggatggttcctataac
attcgaaaagatgacatcatagctctttacccacagttaatgcacttggatcctgaaatc
tacccagaccctttgacttttaaatacgaccggtaccttgatgaaagtgggaaagcaaag
accaccttctatagaaatggaaacaagctgaagtatttctacatgccctttggatcagga
gctacaatatgtcctggaagactatttgctgtccaagaaatcaagcaatttttgattctg
atgctgtcttactttgaactggagcttgtagagagccacaccaagtgtccccctctagat
cagtcccgggcaggcttgggaattttgccaccactaaatgatattgagtttaaatataaa
ctgaaacactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (57)   

Download RDF
DBGET integrated database retrieval system