KEGG   Mus musculus (house mouse): 13836
Entry
13836             CDS       T01002                                 
Symbol
Epha2, Eck, Myk2, Sek-2, Sek2
Name
(RefSeq) Eph receptor A2
  KO
K05103  Eph receptor A2 [EC:2.7.10.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04014  Ras signaling pathway
mmu04015  Rap1 signaling pathway
mmu04151  PI3K-Akt signaling pathway
mmu04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    13836 (Epha2)
   04014 Ras signaling pathway
    13836 (Epha2)
   04015 Rap1 signaling pathway
    13836 (Epha2)
   04151 PI3K-Akt signaling pathway
    13836 (Epha2)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    13836 (Epha2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    13836 (Epha2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     13836 (Epha2)
Protein kinases [BR:mmu01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   13836 (Epha2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_1 SAM_2 Pur_ac_phosph_N Interfer-bind ABC1 Ephrin_rec_like Haspin_kinase CD34_antigen
Other DBs
NCBI-GeneID: 13836
NCBI-ProteinID: NP_034269
MGI: 95278
Ensembl: ENSMUSG00000006445
UniProt: Q03145
Structure
Position
4:141028532..141056695
AA seq 977 aa
MELRAVGFCLALLWGCALAAAAAQGKEVVLLDFAAMKGELGWLTHPYGKGWDLMQNIMDD
MPIYMYSVCNVVSGDQDNWLRTNWVYREEAERIFIELKFTVRDCNSFPGGASSCKETFNL
YYAESDVDYGTNFQKRQFTKIDTIAPDEITVSSDFEARNVKLNVEERMVGPLTRKGFYLA
FQDIGACVALLSVRVYYKKCPEMLQSLARFPETIAVAVSDTQPLATVAGTCVDHAVVPYG
GEGPLMHCTVDGEWLVPIGQCLCQEGYEKVEDACRACSPGFFKSEASESPCLECPEHTLP
STEGATSCQCEEGYFRAPEDPLSMSCTRPPSAPNYLTAIGMGAKVELRWTAPKDTGGRQD
IVYSVTCEQCWPESGECGPCEASVRYSEPPHALTRTSVTVSDLEPHMNYTFAVEARNGVS
GLVTSRSFRTASVSINQTEPPKVRLEDRSTTSLSVTWSIPVSQQSRVWKYEVTYRKKGDA
NSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSTEGSANMAVIG
GVAVGVVLLLVLAGVGLFIHRRRRNLRARQSSEDVRFSKSEQLKPLKTYVDPHTYEDPNQ
AVLKFTTEIHPSCVARQKVIGAGEFGEVYKGTLKASSGKKEIPVAIKTLKAGYTEKQRVD
FLSEASIMGQFSHHNIIRLEGVVSKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGM
LRGIASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKI
PIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTP
MDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTS
GSEGVPFRTVSEWLESIKMQQYTEHFMVAGYTAIEKVVQMSNEDIKRIGVRLPGHQKRIA
YSLLGLKDQVNTVGIPI
NT seq 2934 nt   +upstreamnt  +downstreamnt
atggagctccgggcagtcggtttctgcctggcgctgctgtggggttgcgcgctggcggcc
gcggcggcacagggaaaggaagttgttttgttggacttcgcagcaatgaagggagagctc
ggctggctcacgcacccctatggcaaagggtgggacctgatgcagaacatcatggacgac
atgcctatctacatgtactcggtgtgcaacgtggtatccggcgaccaggacaactggctc
cgcaccaactgggtgtaccgggaggaggccgagcgcatctttattgagctcaagttcacg
gtgcgagactgtaacagcttcccgggtggcgccagctcatgcaaagagaccttcaacctc
tactatgcagagtcagatgtggactatggcaccaacttccagaagcgccagttcaccaag
attgacaccatcgcccctgacgagatcacggtcagcagtgacttcgaggctcgcaatgtc
aagctgaacgtagaggagcgcatggtggggccccttacccggaagggcttctacctggcc
ttccaggacatcggcgcctgcgtggcgctgctctccgttcgcgtctactacaagaagtgt
cccgagatgctgcagagcttggctcgcttccccgagaccattgctgtcgctgtctccgat
acacaacccctggccacggtggccggtacctgcgtggaccatgccgtggtgccttatggg
ggcgaggggcctctcatgcactgcacggtggatggcgagtggctggtgcccatcgggcag
tgcctgtgccaggaaggctacgagaaggtcgaggatgcctgccgagcctgttctccagga
ttcttcaagtctgaggcatctgagagcccttgcctggagtgtccagagcataccctgcca
tccacagagggtgccacctcctgccagtgtgaagaaggctatttcagggcacctgaggac
ccactgtccatgtcttgcacacgtccaccctctgcccccaactacctcacggccattggc
atgggtgccaaagtagaactgcgttggacagctcccaaggacactggtggccgccaggac
attgtctacagtgtcacttgcgaacagtgctggccagagtctggcgagtgtgggccctgt
gaggcgagcgtgcgctattcagaacctcctcacgccctgacccgcacgagtgtgacagtc
agtgacctggagccccacatgaactataccttcgctgtcgaagcacgcaatggtgtctca
ggcctggtgactagccgaagcttccggactgccagcgtcagtattaaccaaacagagccc
cccaaagtgaggctggaggaccgaagcaccacctccctgagtgtcacctggagcatcccg
gtgtcacagcagagccgtgtgtggaagtacgaagtcacctaccgcaagaagggggatgcc
aacagctataatgtgcgccgcacggaaggcttctccgtgaccctggatgaccttgctccg
gataccacgtacctggtgcaggtgcaggcgctgacgcaggagggccagggagccggcagc
aaagtgcacgagttccagacactgtccacggaaggatctgccaacatggcggtgatcggc
ggtgtggctgtaggtgttgttttgcttctggtactggcaggagttggcctcttcatccat
cgaaggaggaggaacctgcgggctcgccagtcctctgaggatgtccgtttttccaagtca
gaacaactaaagcccctgaagacctatgtggatcctcacacttacgaagaccccaaccag
gctgtactcaagtttaccaccgagatccacccatcctgtgtggcaaggcagaaggtcatt
ggagcaggagagtttggagaggtctataaagggacgctgaaggcatcctcggggaagaag
gagataccggtggccatcaagacactgaaagcgggctacactgagaagcagcgggtggac
ttcctgagcgaggccagcatcatgggccagtttagccaccacaatatcatccgcctggag
ggcgtggtctctaaatacaaacccatgatgattatcacagagtacatggagaatggagcg
ctagacaagttccttagggagaaggatggtgagttcagtgtacttcagttggtgggcatg
ctgaggggtatcgcatccggcatgaagtacctggccaacatgaactacgtgcaccgggac
ctggccgcccgcaacatcctcgtcaacagcaacctggtgtgcaaggtgtccgattttggc
ctgtcgcgtgtgctggaagatgaccccgaggccacctacaccacaagtggcggcaagatc
cctattcgatggacagccccagaggccatttcctaccgcaagttcacctcagccagcgat
gtgtggagctacggcattgtcatgtgggaagtgatgacttatggcgaacggccctactgg
gaactgtcaaaccacgaggtcatgaaagccatcaacgacggcttccggctccctacgccc
atggactgcccttcagccatttaccagctcatgatgcagtgctggcagcaagagcgctcc
cgccgacccaagtttgccgacatcgttagcatcctggacaagctcatccgagcccccgac
tccctcaagacgctggctgactttgatccccgagtgtccatccggctgcccagcaccagc
ggctcggagggagtccccttccgtacggtgtccgagtggctggagagcatcaagatgcaa
cagtacacggaacacttcatggtggctggctacacggccatcgagaaggtggtacagatg
tccaacgaagacatcaaaaggatcggagtgcgtcttcctggccaccagaagcgtattgcc
tacagcctgctgggactcaaggaccaggtcaacacagtggggattcctatctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (29)   
   RefSeq(nuc) (3)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (13)   
   Pfam (13)   
All databases (73)   

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