KEGG   Mus musculus (house mouse): 13849
Entry
13849             CDS       T01002                                 
Symbol
Ephx1, EH, Eph-1, Eph1, Epxh1, mEH
Name
(RefSeq) epoxide hydrolase 1, microsomal
  KO
K01253  microsomal epoxide hydrolase [EC:3.3.2.9]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu04976  Bile secretion
mmu05204  Chemical carcinogenesis - DNA adducts
mmu05207  Chemical carcinogenesis - receptor activation
mmu05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    13849 (Ephx1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    13849 (Ephx1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    13849 (Ephx1)
   05207 Chemical carcinogenesis - receptor activation
    13849 (Ephx1)
   05208 Chemical carcinogenesis - reactive oxygen species
    13849 (Ephx1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    13849 (Ephx1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.9  microsomal epoxide hydrolase
     13849 (Ephx1)
Peptidases and inhibitors [BR:mmu01002]
 Serine peptidases
  Family S33
   13849 (Ephx1)
SSDB
Motif
Pfam: EHN Abhydrolase_1 Abhydrolase_6
Other DBs
NCBI-GeneID: 13849
NCBI-ProteinID: NP_034275
MGI: 95405
Ensembl: ENSMUSG00000038776
UniProt: Q9D379
Position
1:complement(180817121..180845134)
AA seq 455 aa
MWLELILASVLGFVIYWFVSRDKEETLPLEDGWWGPGSKPSAKEDESIRPFKVETSDEEI
KDLHQRIDRFRASPPLEGSRFHYGFNSSYLKKVVSFWRNEFDWRKQVEILNQYPHFKTKI
EGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKTHGLSDEHVFEV
ICPSIPGYGFSEASSKKGLNSVATARIFYKLMSRLGFQKFYIQGGDWGSLICTNIAQMVP
NHVKGLHLNMSFISRNIYSLTPLLGQRFGRFLGYTEKDLELLYPFKEKVFYNIMRESGYL
HIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLEDLLTNIMI
YWTTGTIVSSQRFYKENLGQGVMVHRHEGMKVFVPTGYSAFPSEILHAPEKWVKVKYPKL
ISYSYMERGGHFAAFEEPKLLAQDIRKFVSLAELQ
NT seq 1368 nt   +upstreamnt  +downstreamnt
atgtggctggaactcatcctggcttctgtgctgggctttgtcatctactggtttgtctcc
cgggacaaggaggagaccttaccacttgaagatgggtggtggggcccagggtcaaagcca
tcagccaaagaagatgagagcatccggcccttcaaggtggaaacatcagatgaggagatc
aaggacttgcaccagaggatagataggttccgggcatccccacctttggagggcagtcgc
ttccactatggcttcaactccagctacctgaagaaagtggtgtccttctggaggaatgag
tttgactggaggaagcaggtggagatcctcaaccaatacccacactttaagaccaagatt
gaagggctggacatccacttcatccacgtgaaacctccccagctgccctcaggccgcact
ccaaagcccttgctgatggtgcacggctggcctggctccttctatgagttctacaagatt
atcccactgctgacagaccccaagacccacggcctgagtgatgagcacgtgtttgaagtc
atctgtccctcaattcctggctatggcttctcagaggcatccagcaagaaaggtttaaat
tcggtggccactgcgaggatcttctacaagctgatgtcacggctgggcttccagaagttc
tacattcaaggcggcgactgggggtctctcatctgcaccaacatagcccagatggtgccc
aaccacgtgaaaggtttgcacttgaatatgtctttcatttcaagaaacatttattccctg
acccctctcctgggccaacgttttgggagatttcttggctacacagagaaggatctggag
ctcttgtacccattcaaggaaaaggttttctacaacatcatgagggagagtggctactta
cacatccaggccaccaagccggacactgtgggctgtgctctgaatgactctcctgtgggc
ctggctgcctacatcttagagaagttctccacctggaccaagtcagaataccgtgaactg
gaggatggaggcctggagaggaagttctccctggaagatctgctgactaacatcatgatc
tactggacgacaggaaccattgtctcctcccagcgcttctacaaggaaaacttgggccag
ggtgtcatggtccatagacatgaggggatgaaggtctttgtgcccactggctattcagcc
ttcccttctgagatcctgcatgccccagaaaagtgggtgaaggtcaagtaccccaaactc
atctcctattcctacatggaacgtgggggccactttgctgccttcgaagagcccaagctt
ctggcccaggacatccgcaagttcgtgtccctggctgagctgcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (10)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (88)   
   RefSeq(nuc) (2)   
   GenBank (43)   
   EMBL (43)   
Protein domain (3)   
   Pfam (3)   
All databases (143)   

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