KEGG   Mus musculus (house mouse): 14255
Entry
14255             CDS       T01002                                 
Symbol
Flt3, B230315G04, CD135, Flk-2, Flk2, Flt-3, Ly72, wmfl
Name
(RefSeq) FMS-like tyrosine kinase 3
  KO
K05092  fms-related tyrosine kinase 3 [EC:2.7.10.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04014  Ras signaling pathway
mmu04151  PI3K-Akt signaling pathway
mmu04640  Hematopoietic cell lineage
mmu05200  Pathways in cancer
mmu05202  Transcriptional misregulation in cancer
mmu05221  Acute myeloid leukemia
mmu05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    14255 (Flt3)
   04014 Ras signaling pathway
    14255 (Flt3)
   04151 PI3K-Akt signaling pathway
    14255 (Flt3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    14255 (Flt3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    14255 (Flt3)
   05202 Transcriptional misregulation in cancer
    14255 (Flt3)
   05230 Central carbon metabolism in cancer
    14255 (Flt3)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    14255 (Flt3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    14255 (Flt3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mmu04090]
    14255 (Flt3)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     14255 (Flt3)
Protein kinases [BR:mmu01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   14255 (Flt3)
CD molecules [BR:mmu04090]
 Proteins
  14255 (Flt3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase ig Ig_3 I-set Ig_2 Haspin_kinase APH
Other DBs
NCBI-GeneID: 14255
NCBI-ProteinID: NP_034359
MGI: 95559
Ensembl: ENSMUSG00000042817
UniProt: Q00342 Q3UEW6 Q3TQF1
Position
5:complement(147267551..147337299)
AA seq 1000 aa
MRALAQRSDRRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRMVRGS
PEDLQCAPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQPHFD
LQNRGIVSMAILNVTETQAGEYLLHIQSEAANYTVLFTVNVRDTQLYVLRRPYFRKMENQ
DALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKVLHELFGTDIRCCARNALGR
ECTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELEDKALEEGSYFE
MSTYSTNRTMIRILLAFVSSVGRNDTGYYTCSSSKHPSQSALVTILEKGFINATSSQEEY
EIDPYEKFCFSVRFKAYPRIRCTWIFSQASFPCEQRGLEDGYSISKFCDHKNKPGEYIFY
AENDDAQFTKMFTLNIRKKPQVLANASASQASCSSDGYPLPSWTWKKCSDKSPNCTEEIP
EGVWNKKANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFLNSPGPFPFIQ
DNISFYATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYVDFRDYEY
DLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADSCEKEALM
SELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFK
EHNFSFYPTFQAHSNSSMPGSREVQLHPPLDQLSGFNGNLIHSEDEIEYENQKRLAEEEE
EDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIL
SDSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDAN
FYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEEAMYQN
MGGNVPEHPSIYQNRRPLSREAGSEPPSPQAQVKIHGERS
NT seq 3003 nt   +upstreamnt  +downstreamnt
atgcgggcgttggcgcagcgcagcgaccggcggctgctgctgcttgttgttttgtcagta
atgattcttgagaccgttacaaaccaagacctgcctgtgatcaagtgtgttttaatcagt
catgagaacaatggctcatcagcgggaaagccatcatcgtaccgaatggtgcgaggatcc
ccagaagacctccagtgtgccccgaggcgccagagtgaagggacggtatatgaagcggcc
accgtggaggtggccgagtctgggtccatcaccctgcaagtgcagctcgccaccccaggg
gacctttcctgcctctgggtctttaagcacagctccctgggctgccagccgcactttgat
ttacaaaacagaggaatcgtttccatggccatcttgaacgtgacagagacccaggcagga
gaatacctactccatattcagagcgaagccgccaactacacagtactgttcacagtgaat
gtaagagatacacagctgtacgtgctaagaagaccttactttaggaagatggaaaaccag
gacgcactgctctgcatctccgagggtgttccagagcccactgtggagtgggtgctctgc
agctcccacagggaaagctgtaaagaagaaggccctgctgttgtcagaaaggaggaaaag
gtacttcatgagttgttcggaacagacatcagatgctgtgctagaaatgcactgggccgc
gaatgcaccaagctgttcaccatagatctaaaccaggctcctcagagcacactgccccag
ttattcctgaaagtgggggaacccttgtggatcaggtgtaaggccatccatgtgaaccat
ggattcgggctcacctgggagctggaagacaaagccctggaggagggcagctactttgag
atgagtacctactccacaaacaggaccatgattcggattctcttggcctttgtgtcttcc
gtgggaaggaacgacaccggatattacacctgctcttcctcaaagcaccccagccagtca
gcgttggtgaccatcctagaaaaagggtttataaacgctaccagctcgcaagaagagtat
gaaattgacccgtacgaaaagttctgcttctcagtcaggtttaaagcgtacccacgaatc
cgatgcacgtggatcttctctcaagcctcatttccttgtgaacagagaggcctggaggat
gggtacagcatatctaaattttgcgatcataagaacaagccaggagagtacatattctat
gcagaaaatgatgacgcccagttcaccaaaatgttcacgctgaatataagaaagaaacct
caagtgctagcaaatgcctcagccagccaggcgtcctgttcctctgatggctacccgcta
ccctcttggacctggaagaagtgttcggacaaatctcccaattgcacggaggaaatccca
gaaggagtttggaataaaaaggctaacagaaaagtgtttggccagtgggtgtcgagcagt
actctaaatatgagtgaggccgggaaagggcttctggtcaaatgctgtgcgtacaattct
atgggcacgtcttgcgaaaccatctttttaaactcaccaggccccttccctttcatccaa
gacaacatctccttctatgcgaccattgggctctgtctccccttcattgttgttctcatt
gtgttgatctgccacaaatacaaaaagcaatttaggtacgagagtcagctgcagatgatc
caggtgactggccccctggataacgagtacttctacgttgacttcagggactatgaatat
gaccttaagtgggagttcccgagagagaacttagagtttgggaaggtcctggggtctggc
gctttcgggagggtgatgaacgccacggcctatggcattagtaaaacgggagtctcaatt
caggtggcggtgaagatgctaaaagagaaagctgacagctgtgaaaaagaagctctcatg
tcggagctcaaaatgatgacccacctgggacaccatgacaacatcgtgaatctgctgggg
gcatgcacactgtcagggccagtgtacttgatttttgaatattgttgctatggtgacctc
ctcaactacctaagaagtaaaagagagaagtttcacaggacatggacagagatttttaag
gaacataatttcagtttttaccctactttccaggcacattcaaattccagcatgcctggt
tcacgagaagttcagttacacccgcccttggatcagctctcagggttcaatgggaattta
attcattctgaagatgagattgaatatgaaaaccagaagaggctggcagaagaagaggag
gaagatttgaacgtgctgacgtttgaagacctcctttgctttgcgtaccaagtggccaaa
ggcatggaattcctggagttcaagtcgtgtgtccacagagacctggcagccaggaatgtg
ttggtcacccacgggaaggtggtgaagatctgtgactttggactggcccgagacatcctg
agcgactccagctacgtcgtcaggggcaacgcacggctgccggtgaagtggatggcacct
gagagcttatttgaagggatctacacaatcaagagtgacgtctggtcctacggcatcctt
ctctgggagatattttcactgggtgtgaacccttaccctggcattcctgtcgacgctaac
ttctataaactgattcagagtggatttaaaatggagcagccattctatgccacagaaggg
atatactttgtaatgcaatcctgctgggcttttgactcaaggaagcggccatccttcccc
aacctgacttcatttttaggatgtcagctggcagaggcagaagaagcgatgtatcagaac
atgggtggcaacgtcccagaacatccatccatctaccaaaacaggcggcccctcagcaga
gaggcaggctcagagccgccatcgccacaggcccaggtgaagattcacggagaaagaagt
tag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (20)   
   RefSeq(nuc) (4)   
   GenBank (8)   
   EMBL (8)   
Protein domain (8)   
   Pfam (8)   
All databases (72)   

Download RDF
DBGET integrated database retrieval system