KEGG   Mus musculus (house mouse): 14828
Entry
14828             CDS       T01002                                 
Symbol
Hspa5, Bip, D2Wsu141e, D2Wsu17e, Grp78, Hsce70, SEZ-7, Sez7, baffled, mBiP
Name
(RefSeq) heat shock protein 5
  KO
K09490  endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03060  Protein export
mmu04141  Protein processing in endoplasmic reticulum
mmu04612  Antigen processing and presentation
mmu04918  Thyroid hormone synthesis
mmu05012  Parkinson disease
mmu05014  Amyotrophic lateral sclerosis
mmu05020  Prion disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    14828 (Hspa5)
   04141 Protein processing in endoplasmic reticulum
    14828 (Hspa5)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    14828 (Hspa5)
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    14828 (Hspa5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    14828 (Hspa5)
   05014 Amyotrophic lateral sclerosis
    14828 (Hspa5)
   05020 Prion disease
    14828 (Hspa5)
   05022 Pathways of neurodegeneration - multiple diseases
    14828 (Hspa5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    14828 (Hspa5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    14828 (Hspa5)
   04131 Membrane trafficking [BR:mmu04131]
    14828 (Hspa5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    14828 (Hspa5)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.10  non-chaperonin molecular chaperone ATPase
     14828 (Hspa5)
Chaperones and folding catalysts [BR:mmu03110]
 Heat shock proteins
  HSP70 / DNAK
   14828 (Hspa5)
Membrane trafficking [BR:mmu04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    14828 (Hspa5)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   14828 (Hspa5)
  Exosomal proteins of other body fluids (saliva and urine)
   14828 (Hspa5)
  Exosomal proteins of colorectal cancer cells
   14828 (Hspa5)
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A FtsA DDR FGGY_C ParM_N Tombus_movement
Other DBs
NCBI-GeneID: 14828
NCBI-ProteinID: NP_001156906
MGI: 95835
Ensembl: ENSMUSG00000026864
UniProt: P20029
Position
2:34662102..34666541
AA seq 655 aa
MMKFTVVAAALLLLGAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGGPPPTGEEDTSEKDEL
NT seq 1968 nt   +upstreamnt  +downstreamnt
atgatgaagttcactgtggtggcggcggcgttgctgctgctgggcgcggtgcgggccgag
gaggaggacaagaaggaggatgtgggcacggtggtcggcatcgacttggggaccacctat
tcctgcgtcggtgtgttcaagaacggccgcgtggagatcatagccaacgatcagggcaac
cgcatcacgccgtcgtatgtggccttcactcctgaaggggagcgtctgattggcgatgcg
gccaagaaccaactcacgtccaaccccgagaacacggtcttcgatgccaagcgcctcatc
ggacgcacttggaatgacccttcggtgcagcaggacatcaagttcttgccattcaaggtg
gttgaaaagaaaactaaaccgtacattcaagttgatattggaggtgggcaaaccaagaca
tttgccccagaagaaatttctgccatggttctcactaaaatgaaggagactgctgaggcg
tatttgggaaagaaggttacccatgcagttgttactgtaccagcttacttcaatgatgcc
cagcgacaagcaaccaaagatgctggcactattgctggactgaatgtcatgaggatcatc
aatgagcctacagcagctgctattgcatatggcctggataagagagagggagagaagaac
atccttgtgtttgacctgggtggcggcaccttcgatgtgtctcttctcaccattgacaat
ggtgtctttgaagtggtggccactaatggagatactcacctgggtggggaagactttgat
cagcgggtcatggaacacttcatcaagttgtacaaaaagaaaactggtaaagatgttagg
aaagacaacagagctgtgcagaaactccggcgtgaggtagaaaaggctaagagagccttg
tcttctcagcatcaagcaaggattgaaattgagtccttcttcgaaggagaagacttctca
gagacccttactcgggccaaatttgaagagctgaacatggacctgttccgctctaccatg
aagcctgtccagaaagtgttggaagactctgatctgaagaaatctgatattgatgaaatt
gttctggttggtggatctactcgaattccaaagattcagcaactggtgaaagagttcttc
aatggcaaggagccatcccgtggcataaaccccgatgaggctgtagcctatggtgccgct
gtccaggctggtgtcctctctggtgatcaggatacaggtgatctggtactgcttgatgtt
tgtccccttacacttggtattgaaactgtgggaggagtcatgacaaaactgattccaagg
aacactgtggtacccaccaagaagtctcagatcttctccacggcttccgataatcagcca
actgtaacaatcaaggtctatgaaggtgaacgacccctaacaaaagacaatcatcttctg
ggtacatttgatctgactggaattcctcctgctccccgtggagttccccagattgaagtc
acttttgagatagatgttaatggtattctccgagtgacagctgaagacaaaggtacagga
aacaaaaacaaaatcacaattaccaatgaccaaaaccgcctgacacctgaagaaattgaa
aggatggttaatgatgctgagaagtttgctgaggaagacaaaaagctcaaagagcgcatt
gacaccaggaatgaattggaaagctatgcttattctctcaagaaccagattggagataaa
gaaaagctgggaggtaaactttcttctgaagataaagaaaccatggaaaaagctgtagag
gaaaagattgaatggctggaaagccaccaggatgcggacattgaagactttaaagccaaa
aagaaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtggaggc
cctcccccaactggtgaagaggatacatcagaaaaagatgagttgtag

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