KEGG   Mus musculus (house mouse): 14857
Entry
14857             CDS       T01002                                 
Symbol
Gsta1, Gst2-1
Name
(RefSeq) glutathione S-transferase, alpha 1 (Ya)
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00480  Glutathione metabolism
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu00982  Drug metabolism - cytochrome P450
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01524  Platinum drug resistance
mmu05200  Pathways in cancer
mmu05204  Chemical carcinogenesis - DNA adducts
mmu05207  Chemical carcinogenesis - receptor activation
mmu05208  Chemical carcinogenesis - reactive oxygen species
mmu05225  Hepatocellular carcinoma
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    14857 (Gsta1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    14857 (Gsta1)
   00982 Drug metabolism - cytochrome P450
    14857 (Gsta1)
   00983 Drug metabolism - other enzymes
    14857 (Gsta1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    14857 (Gsta1)
   05204 Chemical carcinogenesis - DNA adducts
    14857 (Gsta1)
   05207 Chemical carcinogenesis - receptor activation
    14857 (Gsta1)
   05208 Chemical carcinogenesis - reactive oxygen species
    14857 (Gsta1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    14857 (Gsta1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    14857 (Gsta1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    14857 (Gsta1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    14857 (Gsta1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     14857 (Gsta1)
Transporters [BR:mmu02000]
 Other transporters
  Pores ion channels [TC:1]
   14857 (Gsta1)
SSDB
Motif
Pfam: GST_C GST_C_3 GST_N GST_N_2 GST_N_3
Other DBs
NCBI-GeneID: 14857
NCBI-ProteinID: NP_032207
MGI: 1095417
Ensembl: ENSMUSG00000074183
UniProt: P13745
Structure
Position
9:78137951..78149965
AA seq 223 aa
MAGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEI
DGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAK
TALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPL
LKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFKIQ
NT seq 672 nt   +upstreamnt  +downstreamnt
atggccgggaagcccgtgcttcactacttcaatgcccggggcagaatggagtgcatcagg
tggctcctggctgcagcaggggtggagtttgaagagaagtttatacagagtccggaagat
ttggaaaagctaaaaaaagatgggaatttgatgtttgaccaagtgcccatggtggagatt
gatgggatgaagctggcgcagaccagagccattctcaactacatcgccaccaaatatgac
ctctatgggaaggacatgaaggagagagccctgattgacatgtattcagaaggtatttta
gatctgactgaaatgattgggcaattggtattatgtcccccagaccaaagagaagccaag
actgccttggcaaaagataggaccaaaaaccgttacttgcctgcctttgaaaaggtgttg
aagagccatggacaagactaccttgtgggcaacaggctgaccagggtggacatccaccta
ctggaagttctcctctatgttgaagagtttgatgccagccttctgacccctttccctctg
ctgaaggccttcaagagcagaatcagcagcctccccaatgtgaagaagttcctacagcct
ggcagccagagaaagcctcccatggatgcaaaacaaattcaagaagcaaggaaggctttc
aagattcagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (113)   

Download RDF
DBGET integrated database retrieval system