KEGG   Mus musculus (house mouse): 14961
Entry
14961             CDS       T01002                                 
Symbol
H2-Ab1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1
Name
(RefSeq) histocompatibility 2, class II antigen A, beta 1
  KO
K06752  MHC class II antigen
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04145  Phagosome
mmu04514  Cell adhesion molecules
mmu04612  Antigen processing and presentation
mmu04640  Hematopoietic cell lineage
mmu04658  Th1 and Th2 cell differentiation
mmu04659  Th17 cell differentiation
mmu04672  Intestinal immune network for IgA production
mmu04940  Type I diabetes mellitus
mmu05140  Leishmaniasis
mmu05145  Toxoplasmosis
mmu05150  Staphylococcus aureus infection
mmu05152  Tuberculosis
mmu05164  Influenza A
mmu05166  Human T-cell leukemia virus 1 infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05310  Asthma
mmu05320  Autoimmune thyroid disease
mmu05321  Inflammatory bowel disease
mmu05322  Systemic lupus erythematosus
mmu05323  Rheumatoid arthritis
mmu05330  Allograft rejection
mmu05332  Graft-versus-host disease
mmu05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    14961 (H2-Ab1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    14961 (H2-Ab1)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    14961 (H2-Ab1)
   04612 Antigen processing and presentation
    14961 (H2-Ab1)
   04658 Th1 and Th2 cell differentiation
    14961 (H2-Ab1)
   04659 Th17 cell differentiation
    14961 (H2-Ab1)
   04672 Intestinal immune network for IgA production
    14961 (H2-Ab1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    14961 (H2-Ab1)
   05164 Influenza A
    14961 (H2-Ab1)
   05168 Herpes simplex virus 1 infection
    14961 (H2-Ab1)
   05169 Epstein-Barr virus infection
    14961 (H2-Ab1)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    14961 (H2-Ab1)
   05152 Tuberculosis
    14961 (H2-Ab1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    14961 (H2-Ab1)
   05140 Leishmaniasis
    14961 (H2-Ab1)
  09163 Immune disease
   05310 Asthma
    14961 (H2-Ab1)
   05322 Systemic lupus erythematosus
    14961 (H2-Ab1)
   05323 Rheumatoid arthritis
    14961 (H2-Ab1)
   05320 Autoimmune thyroid disease
    14961 (H2-Ab1)
   05321 Inflammatory bowel disease
    14961 (H2-Ab1)
   05330 Allograft rejection
    14961 (H2-Ab1)
   05332 Graft-versus-host disease
    14961 (H2-Ab1)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    14961 (H2-Ab1)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    14961 (H2-Ab1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    14961 (H2-Ab1)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   14961 (H2-Ab1)
  Exosomal proteins of epithelial cells
   14961 (H2-Ab1)
  Exosomal proteins of breast milk
   14961 (H2-Ab1)
SSDB
Motif
Pfam: MHC_II_beta C1-set Ig_3 C2-set_2 ig MHC_I
Other DBs
NCBI-GeneID: 14961
NCBI-ProteinID: NP_996988
MGI: 103070
Ensembl: ENSMUSG00000073421
UniProt: P14483 Q3TD53 Q8BPA0
Structure
Position
17:34482201..34488392
AA seq 265 aa
MALQIPSLLLSAAVVVLMVLSSPGTEGGDSERHFVYQFMGECYFTNGTQRIRYVTRYIYN
REEYVRYDSDVGEHRAVTELGRPDAEYWNSQPEILERTRAELDTVCRHNYEGPETHTSLR
RLEQPNVVISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGD
WTFQVLVMLEMTPRRGEVYTCHVEHPSLKSPITVEWRAQSESAWSKMLSGIGGCVLGVIF
LGLGLFIRHRSQKGPRGPPPAGLLQ
NT seq 798 nt   +upstreamnt  +downstreamnt
atggctctgcagatccccagcctcctcctctcggctgctgtggtggtgctgatggtgctg
agcagcccagggactgagggcggagactccgaaaggcatttcgtgtaccagttcatgggc
gagtgctacttcaccaacgggacgcagcgcatacgatatgtgaccagatacatctacaac
cgggaggagtacgtgcgctacgacagcgacgtgggcgagcaccgcgcggtgaccgagctg
gggcggccagacgccgagtactggaacagccagccggagatcctggagcgaacgcgggcc
gagctggacacggtgtgcagacacaactacgaggggccggagacccacacctccctgcgg
cggcttgaacagcccaatgtcgtcatctccctgtccaggacagaggccctcaaccaccac
aacactctggtctgctcagtgacagatttctacccagccaagatcaaagtgcgctggttc
cggaatggccaggaggagacggtgggggtctcatccacacagcttattaggaatggggac
tggaccttccaggtcctggtcatgctggagatgacccctcggcggggagaggtctacacc
tgtcacgtggagcatcccagcctgaagagccccatcactgtggagtggagggcacagtct
gagtctgcctggagcaagatgttgagcggcatcgggggctgcgtgcttggggtgatcttc
ctcgggcttggccttttcatccgtcacaggagtcagaaaggacctcgaggccctcctcca
gcagggctcctgcagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (24)   
   KEGG PATHWAY (24)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (67)   
   RefSeq(nuc) (1)   
   GenBank (33)   
   EMBL (33)   
3D Structure (15)   
   PDB (15)   
Protein domain (6)   
   Pfam (6)   
All databases (130)   

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