KEGG   Mus musculus (house mouse): 14979
Entry
14979             CDS       T01002                                 
Symbol
Hsd17b8, D17H6S112E, H-2Ke6, H2-Ke6, Ke-6, Ke6, Ring2
Name
(RefSeq) hydroxysteroid 17-beta dehydrogenase 8
  KO
K13370  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00061  Fatty acid biosynthesis
mmu00140  Steroid hormone biosynthesis
mmu01100  Metabolic pathways
mmu01212  Fatty acid metabolism
Module
mmu_M00873  Fatty acid biosynthesis in mitochondria, animals
mmu_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    14979 (Hsd17b8)
   00140 Steroid hormone biosynthesis
    14979 (Hsd17b8)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     14979 (Hsd17b8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     14979 (Hsd17b8)
SSDB
Motif
Pfam: adh_short_C2 adh_short KR Epimerase RNA_pol_Rpb1_4 RmlD_sub_bind
Other DBs
NCBI-GeneID: 14979
NCBI-ProteinID: NP_038571
MGI: 95911
Ensembl: ENSMUSG00000073422
UniProt: P50171
Position
17:complement(34245007..34247029)
AA seq 259 aa
MASQLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSED
GAPRGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDR
VIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQT
AARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLAS
EDSGYITGASVEVSGGLFM
NT seq 780 nt   +upstreamnt  +downstreamnt
atggcgtctcagctccggctccgctctgcgctggccctggtcacaggtgcgggtagcggc
atcggccgtgcgatcagcgtgcgcctagcggcagagggcgccgccgtggccgcctgcgac
ctggacggggccgcggcacaggacacggtgcggctgctgggaagcccggggagcgaggac
ggggcgccgcgcggcaagcacgctgccttccaagcggatgtgtctcagggccccgcagcc
agacgcctgctggaggaagtgcaggcctgcttttctcgcccgccatctgtcgttgtgtcc
tgtgcgggcatcacacgcgatgagtttctgctccacatgtcagaagaagactgggacaga
gtcatagctgtcaacctcaagggcaccttcctagtcactcaggctgcagcccaggcttta
gtgtccagtggcggtcgtggctccatcatcaacattagtagcatcattggaaaggtgggg
aatatcggacaaacgaattatgcgtcgtccaaagcaggagtgattgggctcacccagact
gcggcccgggagcttggacgacatggaatccgatgtaactcggtcctcccagggttcatt
gcaacgcccatgacccagaaaatgccagagaaagtgaaggacaaggtaactgcaatgatt
ccgttgggacacatgggggaccctgaggatgtggcagatgtggttgcattcttggcatct
gaagacagtggatacatcacaggggcctccgtggaagtcagtggaggtcttttcatgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (6)   
   Pfam (6)   
All databases (55)   

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