KEGG   Mus musculus (house mouse): 15182
Entry
15182             CDS       T01002                                 
Symbol
Hdac2, D10Wsu179e, YAF1, Yy1bp, mRPD3
Name
(RefSeq) histone deacetylase 2
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03082  ATP-dependent chromatin remodeling
mmu03083  Polycomb repressive complex
mmu04110  Cell cycle
mmu04213  Longevity regulating pathway - multiple species
mmu04330  Notch signaling pathway
mmu04350  TGF-beta signaling pathway
mmu04613  Neutrophil extracellular trap formation
mmu04919  Thyroid hormone signaling pathway
mmu05016  Huntington disease
mmu05031  Amphetamine addiction
mmu05034  Alcoholism
mmu05165  Human papillomavirus infection
mmu05169  Epstein-Barr virus infection
mmu05200  Pathways in cancer
mmu05202  Transcriptional misregulation in cancer
mmu05203  Viral carcinogenesis
mmu05206  MicroRNAs in cancer
mmu05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    15182 (Hdac2)
   03083 Polycomb repressive complex
    15182 (Hdac2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    15182 (Hdac2)
   04350 TGF-beta signaling pathway
    15182 (Hdac2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    15182 (Hdac2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    15182 (Hdac2)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    15182 (Hdac2)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    15182 (Hdac2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    15182 (Hdac2)
   05202 Transcriptional misregulation in cancer
    15182 (Hdac2)
   05206 MicroRNAs in cancer
    15182 (Hdac2)
   05203 Viral carcinogenesis
    15182 (Hdac2)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    15182 (Hdac2)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    15182 (Hdac2)
   05165 Human papillomavirus infection
    15182 (Hdac2)
  09164 Neurodegenerative disease
   05016 Huntington disease
    15182 (Hdac2)
  09165 Substance dependence
   05031 Amphetamine addiction
    15182 (Hdac2)
   05034 Alcoholism
    15182 (Hdac2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    15182 (Hdac2)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     15182 (Hdac2)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     15182 (Hdac2)
   HDAC complexes
    Sin3A-HDAC complex
     15182 (Hdac2)
    BRAF-HDAC complex
     15182 (Hdac2)
    REST complex
     15182 (Hdac2)
    SHIP complex
     15182 (Hdac2)
    MiDAC complex
     15182 (Hdac2)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     15182 (Hdac2)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    15182 (Hdac2)
  Chromatin remodeling factors
   NuRD complex
    15182 (Hdac2)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 15182
NCBI-ProteinID: NP_032255
MGI: 1097691
Ensembl: ENSMUSG00000019777
UniProt: P70288 A0A0R4J008 Q3TMT1
Position
10:36850293..36877885
AA seq 488 aa
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA
GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH
GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ
IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG
GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM
EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE
FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDPKGA
KSEQLSNP
NT seq 1467 nt   +upstreamnt  +downstreamnt
atggcgtacagtcaaggaggcggcaagaagaaagtgtgctactactatgatggtgatatt
ggcaattattattatggccagggtcatcccatgaagcctcatagaatccggatgactcat
aacttgctgctaaattatggtttataccgaaaaatggaaatatataggcctcataaagcc
actgctgaagaaatgactaaataccacagcgatgagtatatcaagtttctacgatcaata
agaccagataatatgtctgagtacagtaagcagatgcagagatttaacgtcggagaagat
tgtccggtgtttgatggactctttgagttttgtcagctctccacgggtggttcagttgct
ggggctgtgaaattaaaccggcaacaaactgatatggctgtcaattgggctggaggacta
catcatgccaagaagtcagaagcatcagggttctgctatgttaatgatattgtgcttgcc
atcctcgaattacttaagtatcatcagagagtcttatatattgacatagacatccaccat
ggtgatggtgttgaggaagctttttatacaacagatcgcgtgatgaccgtctcattccat
aaatatggggaatactttcctggaacaggagacttgagggatattggtgctggaaaggga
aaatactatgctgtcaattttcccatgagagatggtatagatgatgaatcatatggacaa
atttttaagcctatcatctcaaaagtgatggagatgtaccagcctagcgcggtggtgctg
cagtgtggcgcagactccctgtctggggacaggcttggttgtttcaatctaactgtcaaa
ggtcatgctaaatgtgtagaagtagtgaaaacttttaacttgccattgctgatgctcggt
ggaggaggctacacaatccggaatgttgcccgatgttggacatatgagactgcagttgcc
cttgattgtgaaattcccaatgagttgccatataatgattactttgagtattttggacca
gacttcaaactgcatattagtccttcaaacatgacaaaccagaacactccagaatatatg
gaaaagataaaacagcgtttatttgaaaatctacgtatgttaccacatgcacctggtgtt
caaatgcaagctattccagaggatgctgttcatgaagacagtggagatgaggatggagaa
gacccggacaaaagaatttccattcgagcatcagacaaacggatagcttgcgatgaagag
ttttcagattctgaggatgaaggtgaaggaggtcgtaggaatgttgctgatcataagaaa
ggagcaaagaaggctaggattgaagaagacaagaaggagacagaggacaagaagacagat
gttaaggaagaagacaaatccaaggacaatagtggtgagaaaacagaccccaaaggagcc
aagtcagaacaactcagcaacccttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (12)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (22)   
   RefSeq(nuc) (8)   
   GenBank (7)   
   EMBL (7)   
Protein domain (1)   
   Pfam (1)   
All databases (90)   

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