KEGG   Mus musculus (house mouse): 16194
Entry
16194             CDS       T01002                                 
Symbol
Il6ra, CD126, IL-6R, IL-6R-alpha, IL-6RA, Il6r
Name
(RefSeq) interleukin 6 receptor, alpha
  KO
K05055  interleukin 6 receptor
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu04060  Cytokine-cytokine receptor interaction
mmu04061  Viral protein interaction with cytokine and cytokine receptor
mmu04066  HIF-1 signaling pathway
mmu04151  PI3K-Akt signaling pathway
mmu04630  JAK-STAT signaling pathway
mmu04640  Hematopoietic cell lineage
mmu04659  Th17 cell differentiation
mmu04932  Non-alcoholic fatty liver disease
mmu05163  Human cytomegalovirus infection
mmu05171  Coronavirus disease - COVID-19
mmu05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    16194 (Il6ra)
   04066 HIF-1 signaling pathway
    16194 (Il6ra)
   04151 PI3K-Akt signaling pathway
    16194 (Il6ra)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    16194 (Il6ra)
   04061 Viral protein interaction with cytokine and cytokine receptor
    16194 (Il6ra)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    16194 (Il6ra)
   04659 Th17 cell differentiation
    16194 (Il6ra)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16194 (Il6ra)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    16194 (Il6ra)
   05163 Human cytomegalovirus infection
    16194 (Il6ra)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    16194 (Il6ra)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    16194 (Il6ra)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:mmu04050]
    16194 (Il6ra)
   04090 CD molecules [BR:mmu04090]
    16194 (Il6ra)
Cytokine receptors [BR:mmu04050]
 Interleukin receptor families
  IL6/12 receptor family
   16194 (Il6ra)
CD molecules [BR:mmu04090]
 Proteins
  16194 (Il6ra)
SSDB
Motif
Pfam: IL6Ra-bind ig Ig_3 fn3 V-set I-set
Other DBs
NCBI-GeneID: 16194
NCBI-ProteinID: NP_034689
MGI: 105304
Ensembl: ENSMUSG00000027947
UniProt: P22272 Q3URV7
Position
3:complement(89776631..89820503)
AA seq 460 aa
MLTVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNVTIHW
VYSGSQNREWTTTGNTLVLRDVQLSDTGDYLCSLNDHLVGTVPLLVDVPPEEPKLSCFRK
NPLVNAICEWRPSSTPSPTTKAVLFAKKINTTNGKSDFQVPCQYSQQLKSFSCQVEILEG
DKVYHIVSLCVANSVGSKSSHNEAFHSLKMVQPDPPANLVVSAIPGRPRWLKVSWQHPET
WDPSYYLLQFQLRYRPVWSKEFTVLLLPVAQYQCVIHDALRGVKHVVQVRGKEELDLGQW
SEWSPEVTGTPWIAEPRTTPAGILWNPTQVSVEDSANHEDQYESSTEATSVLAPVQESSS
MSLPTFLVAGGSLAFGLLLCVFIILRLKQKWKSEAEKESKTTSPPPPPYSLGPLKPTFLL
VPLLTPHSSGSDNTVNHSCLGVRDAQSPYDNSNRDYLFPR
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgctgaccgtcggctgcacgctgttggtcgccctgctggccgcgcccgcggtcgcgctg
gtcctcgggagctgccgcgcgctggaggtggcaaatggcacagtgacaagcctgccaggg
gccaccgttaccctgatttgccccgggaaggaagcagcaggcaatgttaccattcactgg
gtgtactctggctcacaaaacagagaatggactaccacaggaaacacactggttctgagg
gacgtgcagctcagcgacactggggactatttatgctccctgaatgatcacctggtgggg
actgtgcccttgctggtggatgttcccccagaggagcccaagctctcctgcttccggaag
aacccccttgtcaacgccatctgtgagtggcgtccgagcagcaccccctctccaaccacg
aaggctgtgctgtttgcaaagaaaatcaacaccaccaacgggaagagtgacttccaggtg
ccctgtcagtattctcagcagctgaaaagcttctcctgccaggtggagatcctggagggt
gacaaagtataccacatagtgtcactgtgcgttgcaaacagtgtgggaagcaagtccagc
cacaacgaagcgtttcacagcttaaaaatggtgcagccggatccacctgccaaccttgtg
gtatcagccatacctggaaggccgcgctggctcaaagtcagctggcagcaccctgagacc
tgggacccgagttactacttgctgcagttccagcttcgataccgacctgtatggtcaaag
gagttcacggtgttgctgctcccggtggcccagtaccaatgcgtcatccatgatgccttg
cgaggagtgaagcacgtggtccaggtccgtgggaaggaggagcttgaccttggccagtgg
agcgaatggtccccagaggtcacgggcactccttggatagcagagcccaggaccaccccg
gcaggaatcctctggaaccccacacaggtctctgttgaagactctgccaaccacgaggat
cagtacgaaagttctacagaagcaacgagtgtcctcgccccagtgcaagaatcctcgtcc
atgtccctgcccacattcctggtagctggaggaagcttggcgtttgggttgcttctctgt
gtcttcatcatcctgagactcaagcagaaatggaagtcagaggctgagaaggaaagcaag
acgacctctcctccacccccaccgtattccttgggcccactgaagccgaccttccttctg
gttcctctcctcaccccacacagctctgggtctgacaataccgtaaaccacagctgcctg
ggtgtcagggacgcacagagcccttatgacaacagcaacagagactacttattccccaga
taa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
Protein domain (6)   
   Pfam (6)   
All databases (63)   

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