| Entry |
|
|---|
| Symbol |
Inpp5d, SHIP, SHIP-1, SHIP1, SIP-145, p150Ship, s-SHIP
|
|---|
| Name |
(RefSeq) inositol polyphosphate-5-phosphatase D
|
|---|
| KO |
| K03084 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86] |
|
|---|
| Organism |
mmu Mus musculus (house mouse)
|
|---|
| Pathway |
| mmu04070 | Phosphatidylinositol signaling system |
| mmu04662 | B cell receptor signaling pathway |
| mmu04664 | Fc epsilon RI signaling pathway |
| mmu04666 | Fc gamma R-mediated phagocytosis |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
16331 (Inpp5d)
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
16331 (Inpp5d)
09150 Organismal Systems
09151 Immune system
04662 B cell receptor signaling pathway
16331 (Inpp5d)
04664 Fc epsilon RI signaling pathway
16331 (Inpp5d)
04666 Fc gamma R-mediated phagocytosis
16331 (Inpp5d)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:mmu04131]
16331 (Inpp5d)
03036 Chromosome and associated proteins [BR:mmu03036]
16331 (Inpp5d)
Enzymes [BR:mmu01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
16331 (Inpp5d)
Membrane trafficking [BR:mmu04131]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
16331 (Inpp5d)
Chromosome and associated proteins [BR:mmu03036]
Eukaryotic type
Histone modification proteins
HDAC complexes
SHIP complex
16331 (Inpp5d)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| Structure |
|
|---|
| Position |
1:87548034..87648232
|
|---|
| AA seq |
1191 aa
MPAMVPGWNHGNITRSKAEELLSRAGKDGSFLVRASESIPRAYALCVLFRNCVYTYRILP
NEDDKFTVQASEGVPMRFFTKLDQLIDFYKKENMGLVTHLQYPVPLEEEDAIDEAEEDTV
ESVMSPPELPPRNIPMSAGPSEAKDLPLATENPRAPEVTRLSLSETLFQRLQSMDTSGLP
EEHLKAIQDYLSTQLLLDSDFLKTGSSNLPHLKKLMSLLCKELHGEVIRTLPSLESLQRL
FDQQLSPGLRPRPQVPGEASPITMVAKLSQLTSLLSSIEDKVKSLLHEGSESTNRRSLIP
PVTFEVKSESLGIPQKMHLKVDVESGKLIVKKSKDGSEDKFYSHKKILQLIKSQKFLNKL
VILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAP
PPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLELLRHSLQEVTSMTF
KTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGF
VNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLNYRVELPTW
EAEAIIQKIKQQQYSDLLAHDQLLLERKDQKVFLHFEEEEITFAPTYRFERLTRDKYAYT
KQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFV
SKNGPGTVDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELV
VRFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLETTEAQHPIYTPL
THHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDESSGMKCLKNLTSHDPMRQWEPSG
RVPACGVSSLNEMINPNYIGMGPFGQPLHGKSTLSPDQQLTAWSYDQLPKDSSLGPGRGE
GPPTPPSQPPLSPKKFSSSTANRGPCPRVQEARPGDLGKVEALLQEDLLLTKPEMFENPL
YGSVSSFPKLVPRKEQESPKMLRKEPPPCPDPGISSPSIVLPKAQEVESVKGTSKQAPVP
VLGPTPRIRSFTCSSSAEGRMTSGDKSQGKPKASASSQAPVPVKRPVKPSRSEMSQQTTP
IPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRQEEGLLGRTAMQ |
|---|
| NT seq |
3576 nt +upstreamnt +downstreamnt
atgcctgccatggtccctgggtggaaccatggcaacatcacccgctccaaggcagaggag
ctactttccagagccggcaaggacgggagcttccttgtgcgtgccagcgagtccatcccc
cgggcctacgcactctgcgtgctgttccggaattgtgtttacacttacaggattctgccc
aatgaggacgataaattcactgttcaggcatccgaaggtgtccccatgaggttcttcacg
aagctggaccagctcatcgacttttacaagaaggaaaacatggggctggtgacccacctg
cagtaccccgtgcccctggaggaggaggatgctattgatgaggctgaggaggacactgta
gaaagtgtcatgtcaccacctgagctgcctcccagaaacattcctatgtctgccgggccc
agcgaggccaaggaccttcctcttgcaacagagaacccccgagcccctgaggtcacccgg
ctgagtctctccgagacactgtttcagcgtctacagagcatggataccagtgggcttccc
gaggagcacctgaaagccatccaggattatctgagcactcagctcctcctggattccgac
tttttgaagacgggctccagcaacctccctcacctgaagaagctgatgtcactgctctgc
aaggagctccatggggaagtcatcaggactctgccatccctggagtctctgcagaggttg
tttgaccaacagctctccccaggccttcgcccacgacctcaggtgcccggagaggccagt
cccatcaccatggttgccaaactcagccaattgacaagtctgctgtcttccattgaagat
aaggtcaagtccttgctgcacgagggctcagaatctaccaacaggcgttcccttatccct
ccggtcacctttgaggtgaagtcagagtccctgggcattcctcagaaaatgcatctcaaa
gtggacgttgagtctgggaaactgatcgttaagaagtccaaggatggttctgaggacaag
ttctacagccacaaaaaaatcctgcagctcattaagtcccagaagtttctaaacaagttg
gtgattttggtggagacggagaaggagaaaatcctgaggaaggaatatgtttttgctgac
tctaagaaaagagaaggcttctgtcaactcctgcagcagatgaagaacaagcattcggag
cagccagagcctgacatgatcaccatcttcattggcacttggaacatgggtaatgcaccc
cctcccaagaagatcacgtcctggtttctctccaaggggcagggaaagacacgggacgac
tctgctgactacatcccccatgacatctatgtgattggcacccaggaggatccccttgga
gagaaggagtggctggagctactcaggcactccctgcaagaagtcaccagcatgacattt
aaaacagttgccatccacaccctctggaacattcgcatagtggtgcttgccaagccagag
catgagaatcggatcagccatatctgcactgacaacgtgaagacaggcatcgccaacacc
ctgggaaacaagggagcagtgggagtgtccttcatgttcaatggaacctccttggggttc
gtcaacagccacttgacttctggaagtgaaaaaaagctcaggagaaatcaaaactatatg
aacatcctgcggttcctggccctgggagacaagaagctaagcccatttaacatcacccac
cgcttcacccacctcttctggcttggggatctcaactaccgcgtggagctgcccacttgg
gaggcagaggccatcatccagaagatcaagcaacagcagtattcagaccttctggcccac
gaccaactgctcctggagaggaaggaccagaaggtcttcctgcactttgaggaggaagag
atcaccttcgcccccacctatcgatttgaaagactgacccgggacaagtatgcatacacg
aagcagaaagcaacagggatgaagtacaacttgccgtcctggtgcgaccgagtcctctgg
aagtcttacccgctggtgcatgtggtctgtcagtcctatggcagtaccagtgacatcatg
acgagtgaccacagccctgtctttgccacgtttgaagcaggagtcacatctcaattcgtc
tccaagaatggtcctggcactgtagatagccaagggcagatcgagtttcttgcatgctac
gccacactgaagaccaagtcccagactaagttctacttggagttccactcaagctgctta
gagagttttgtcaagagtcaggaaggagagaatgaagagggaagtgaaggagagctggtg
gtacggtttggagagactcttcccaagctaaagcccattatctctgaccccgagtactta
ctggaccagcatatcctgatcagcattaaatcctctgacagtgacgagtcctatggtgaa
ggctgcattgcccttcgcttggagaccacagaggctcagcatcctatctacacgcctctc
acccaccatggggagatgactggccacttcaggggagagattaagctgcagacctcccag
ggcaagatgagggagaagctctatgactttgtgaagacagagcgggatgaatccagtgga
atgaaatgcttgaagaacctcaccagccatgaccctatgaggcaatgggagccttctggc
agggtccctgcatgtggtgtctccagcctcaatgagatgatcaatccaaactacattggt
atggggccttttggacagcccctgcatgggaaatcaaccctgtccccagatcagcaactc
acagcttggagttatgaccagctacccaaagactcctccctggggcctgggaggggggag
ggtcctccaacccctccctcccaaccacctctgtcgccaaagaagttttcatcttccaca
gccaaccgaggtccctgccccagggtgcaagaggcaagacctggggatctgggaaaggtg
gaagctctgctccaggaggacctgctgctgacgaagcccgagatgtttgagaacccactg
tatggatccgtgagttccttccctaagctggtgcccaggaaagagcaggagtctcccaag
atgctgcggaaggagcccccgccctgtccagacccaggaatctcatcacccagcatcgtg
ctccccaaagcccaagaggtggagagtgtcaaggggacaagcaaacaggcccctgtgcct
gtccttggccccacaccccggatccgctcctttacctgttcttcttctgctgagggcaga
atgaccagtggggacaagagccaagggaagcccaaggcctcagccagttcccaagcccca
gtgccagtcaagaggcctgtcaagccttccaggtcagaaatgagccagcagacaacaccc
atcccagctccacggccacccctgccagtcaagagtcctgctgtcctgcagctgcaacat
tccaaaggcagagactaccgtgacaacacagaactcccccaccatggcaagcaccgccaa
gaggaggggctgcttggcaggactgccatgcagtga |
|---|
