KEGG   Mus musculus (house mouse): 16798
Entry
16798             CDS       T01002                                 
Symbol
Lats1
Name
(RefSeq) large tumor suppressor
  KO
K08791  serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04390  Hippo signaling pathway
mmu04392  Hippo signaling pathway - multiple species
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    16798 (Lats1)
   04392 Hippo signaling pathway - multiple species
    16798 (Lats1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    16798 (Lats1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     16798 (Lats1)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: AGC group
  NDR family
   16798 (Lats1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr UBA ABC1 Pkinase_C APH Haspin_kinase Cas_Cas6_C Kinase-like UBA_3
Other DBs
NCBI-GeneID: 16798
NCBI-ProteinID: NP_034820
MGI: 1333883
Ensembl: ENSMUSG00000040021
UniProt: Q8BYR2
Structure
Position
10:7556964..7592225
AA seq 1129 aa
MKRGEKPEGYRQMRPKTFPASNYPGSSRQMLQEIRESLRNLSKPSDASKAEHNLNKMSTE
DPRQVRNPPKFGTHHKALQEIRNSLLPFANETSSSRSPSEVNPQMFQDLQAAGFDEDMVI
QALQKTNNRSIEAAVEFISKMSYQDPRREQMSAAAARPINATMKPGNVQHSINRKQSWKG
SKESLVPQRHGPSLGENVVYRSESPNSQADVGRPLSGSGIAAFAQAHPSNGQRVNPPPPP
QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPSSQTKRYSGNMEYVISRISPVPPGAWQEGY
PPPPLTTSPMNPPSQAQRAISSVPVGRQPIIMQSTSKFNFTPGRPGVQNGGGQSDFIVHQ
NVPTGSVTRQPPPPYPLTPANGQSPSALQTGASAAPPSFANGNVPQSMMVPNRNSHNMEL
YNINVPGLQTAWPQSSSAPAQSSPSGGHEIPTWQPNIPVRSNSFNNPLGSRASHSANSQP
SATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWMPQPVQTVQPTPFSEGTASSVP
VIPPVAEAPSYQGPPPPYPKHLLHQNPSVPPYESVSKPCKDEQPSLPKEDDSEKSADSGD
SGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRK
KQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCL
ARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFV
MDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGH
IKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQ
HQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMK
VINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQ
QSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYKNGKHPEHAFYEFTFR
RFFDDNGYPYNYPKPIEYEYIHSQGSEQQSDEDDQHTSSDGNNRDLVYV
NT seq 3390 nt   +upstreamnt  +downstreamnt
atgaagaggggtgaaaagccagaagggtacagacagatgaggcctaagacctttcctgcc
agcaactaccctggcagcagccgacagatgctgcaggagatccgagaatccctgaggaat
ttatcaaaaccatctgatgcttcgaaggccgagcataacctgaataagatgtcgactgaa
gatcccaggcaggtgagaaatccacccaaatttggcacacatcataaagccttgcaagaa
attcgaaactctctactaccatttgcaaatgaaacaagttcttcccggagcccttcagaa
gttaatccacagatgtttcaggatttgcaggctgctggctttgatgaggacatggttatt
caagctcttcagaaaaccaataacagaagcatagaagccgctgttgaattcattagtaaa
atgagttaccaagaccctcgtcgagagcagatgtctgcagcagctgccaggcctattaat
gccaccatgaaaccaggaaatgtgcaacattcaattaaccgaaaacaaagctggaaaggt
tctaaagagtctctagttcctcagagacacggcccatctctaggagaaaatgtggtttat
cgttctgaaagccccaactcacaggcggatgtaggaagacctctgtctggatccggcatt
gcagcatttgctcaagctcacccaagcaatggacagagagtgaaccccccaccaccacct
caagttaggagtgttactcctccaccacctccgagaggccagaccccacctccccgaggc
accactccccctcccccctcatgggaaccaagctctcagacaaagcgctactctgggaac
atggagtacgtaatctcccgaatctcccctgttccacctggggcgtggcaggagggctac
cctccaccacctcttaccacttctcccatgaatccccctagccaggctcagagggccatt
agttctgttccagttggtagacaacccatcatcatgcagagtactagcaaatttaacttt
acaccagggcgacctggagttcagaatggtggtggtcagtctgattttatcgtgcaccaa
aatgtccccactggttctgtgactcggcagccaccacctccatatcctctgaccccagct
aatggacaaagcccctctgctttacaaacaggggcttctgctgctccaccatcattcgcc
aatggaaacgttcctcagtcgatgatggtgcccaacaggaacagtcataacatggagctt
tataatattaatgtccctggactgcaaacagcctggccccagtcgtcttctgctcctgcg
cagtcatccccaagcggtgggcatgaaattcctacatggcaacctaacataccagtgagg
tcaaattcttttaataacccattaggaagtagagcaagtcactctgctaattctcagcct
tctgccactacagtcactgccatcacacccgctcctattcaacagcccgtgaaaagcatg
cgcgtcctgaaaccagagctgcagactgctttagccccaacccatccttcttggatgcca
cagccagttcagactgttcagcctacccctttttctgagggtacagcttcaagtgtgcct
gtcatcccacctgttgctgaagctccaagctatcaaggtccaccaccgccttatccaaaa
catctgctacaccaaaacccatctgtccctccatatgagtcagtaagtaagccctgcaaa
gatgaacagcctagcttacccaaggaagatgatagtgagaagagtgcggacagtggtgac
tctggggataaagaaaagaaacagattacaacttcacctatcactgttcggaaaaacaag
aaagatgaagaacgaagagagtctcggattcagagttactccccacaggcctttaagttc
ttcatggagcagcacgtagagaacgtcctgaagtctcatcagcagcgtctgcatcggaag
aagcagctagaaaatgaaatgatgcgggttggattatctcaagatgcccaggatcaaatg
agaaagatgctttgccagaaagagtctaactatattcgtcttaaaagggctaaaatggac
aagtctatgtttgtaaagataaagacattaggaataggagcgtttggtgaagtctgtcta
gcaagaaaagtcgatactaaagctttgtatgcaacaaagactcttcgaaagaaagacgtt
ctgctccgaaatcaggtggctcatgtgaaagcggagagggatatcctagcagaagccgac
aatgagtgggtggtccgcctgtactactctttccaggacaaggacaacttgtactttgtg
atggactacattcctgggggggatatgatgagcctattaattagaatgggcatctttcct
gaaaatctggcacgattctacatagcagaacttacctgtgcagttgaaagtgttcataaa
atgggttttattcatagagatattaaacctgataacattttgattgaccgtgatggccat
attaaattgactgactttggcttgtgcactggcttcagatggacacatgactccaagtac
taccagagtggggatcacccacggcaagatagcatggatttcagtaacgaatggggagat
ccttccaattgtcggtgtggggacagactgaagccactggagcggagagctgctcgccag
caccagcgatgtctagcccattctctggttgggactcccaattatattgcacctgaagtg
ctactgcgaacaggatatacacagctgtgtgactggtggagtgttggtgttattcttttt
gaaatgttggtgggacaacctcctttcttggcacaaaccccattagaaacacaaatgaag
gttatcaactggcaaacttctcttcacatccctcctcaagctaagctgagtcctgaagcc
tctgacctcattatcaaactttgtcgaggaccagaagaccgcctcggcaagaacggtgct
gatgagataaaggctcatccattttttaagaccatcgatttctctagtgatctgagacag
cagtctgcttcatacatccctaaaatcacgcatccaacagatacatccaatttcgaccct
gttgatcctgataaattgtggagcgatggcagcgaggaggaaaatatcagtgacactctg
aacggatggtataaaaatgggaagcaccccgagcacgctttctatgagttcacctttcgg
aggttttttgatgacaatggctacccatataattatccaaagcctattgagtatgaatac
attcattcacagggctcagaacaacagtctgatgaagatgatcaacacacaagctccgat
ggaaacaaccgagatctagtgtatgtttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (24)   
   RefSeq(nuc) (4)   
   GenBank (10)   
   EMBL (10)   
3D Structure (2)   
   PDB (2)   
Protein domain (10)   
   Pfam (10)   
All databases (81)   

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