KEGG   Mus musculus (house mouse): 16880
Entry
16880             CDS       T01002                                 
Symbol
Lifr, A230075M04Rik, LIF
Name
(RefSeq) LIF receptor alpha
  KO
K05058  leukemia inhibitory factor receptor
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04060  Cytokine-cytokine receptor interaction
mmu04550  Signaling pathways regulating pluripotency of stem cells
mmu04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    16880 (Lifr)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    16880 (Lifr)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    16880 (Lifr)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:mmu04050]
    16880 (Lifr)
   04090 CD molecules [BR:mmu04090]
    16880 (Lifr)
Cytokine receptors [BR:mmu04050]
 Interleukin receptor families
  IL6/12 receptor family
   16880 (Lifr)
CD molecules [BR:mmu04090]
 Proteins
  16880 (Lifr)
SSDB
Motif
Pfam: LIFR_D2 LIF-R_Ig-like LIFR_N fn3 Pur_ac_phosph_N IL6Ra-bind PhoD_N TMEM154
Other DBs
NCBI-GeneID: 16880
NCBI-ProteinID: NP_038612
MGI: 96788
Ensembl: ENSMUSG00000054263
UniProt: P42703
Structure
Position
15:7120091..7226970
AA seq 1092 aa
MAAYSWWRQPSWMVDNKRSRMTPNLPWLLSALTLLHLTMHANGLKRGVQDLKCTTNNMRV
WDCTWPAPLGVSPGTVKDICIKDRFHSCHPLETTNVKIPALSPGDHEVTINYLNGFQSKF
TLNEKDVSLIPETPEILDLSADFFTSSLLLKWNDRGSALPHPSNATWEIKVLQNPRTEPV
ALVLLNTMLSGKDTVQHWNWTSDLPLQCATHSVSIRWHIDSPHFSGYKEWSDWSPLKNIS
WIRNTETNVFPQDKVVLAGSNMTICCMSPTKVLSGQIGNTLRPLIHLYGQTVAIHILNIP
VSENSGTNIIFITDDDVYGTVVFAGYPPDVPQKLSCETHDLKEIICSWNPGRITGLVGPR
NTEYTLFESISGKSAVFHRIEGLTNETYRLGVQMHPGQEIHNFTLTGRNPLGQAQSAVVI
NVTERVAPHDPTSLKVKDINSTVVTFSWYLPGNFTKINLLCQIEICKANSKKEVRNATIR
GAEDSTYHVAVDKLNPYTAYTFRVRCSSKTFWKWSRWSDEKRHLTTEATPSKGPDTWREW
SSDGKNLIVYWKPLPINEANGKILSYNVSCSLNEETQSVLEIFDPQHRAEIQLSKNDYII
SVVARNSAGSSPPSKIASMEIPNDDITVEQAVGLGNRIFLTWRHDPNMTCDYVIKWCNSS
RSEPCLLDWRKVPSNSTETVIESDQFQPGVRYNFYLYGCTNQGYQLLRSIIGYVEELAPI
VAPNFTVEDTSADSILVKWDDIPVEELRGFLRGYLFYFQKGERDTPKTRSLEPHHSDIKL
KNITDISQKTLRIADLQGKTSYHLVLRAYTHGGLGPEKSMFVVTKENSVGLIIAILIPVA
VAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSNALKTLEMNPCTP
NNVEVLESRSIVPKIEDTEIISPVAERPGERSEVDPENHVVVSYCPPIIEEEITNPAADE
VGGASQVVYIDVQSMYQPQAKAEEEQDVDPVVVAGYKPQMRLPISPAVEDTAAEDEEGKT
AGYRPQANVNTWNLVSPDSPRSTDSNNEVVSFGSPCSINSRQFLIPPKDEDSPKSNGGGW
SFTNFFQNKPND
NT seq 3279 nt   +upstreamnt  +downstreamnt
atggcagcttactcatggtggagacagccatcgtggatggtagacaataaaagatcgagg
atgactccaaacctgccatggctcctgtcagctctgaccctcctgcatctgacgatgcat
gcaaacggtctgaagagaggggtacaagacttgaaatgcacaaccaacaacatgcgagtg
tgggactgcacgtggccagctcccctcggggtcagccctggaactgttaaagatatttgc
attaaagacaggttccattcttgtcacccattagagacaacaaacgttaaaattccagct
ctttcacctggtgatcacgaagtcacaataaattatctaaatggctttcagagtaaattc
acgttgaatgaaaaagatgtctctttaattccagagactcccgagatcctggatttgtct
gctgacttcttcacctcctccttactactgaagtggaacgacagagggtctgctctgcct
cacccctccaatgccacctgggagattaaggttctacagaatccaaggacggaaccagta
gcactcgtgttactcaacacaatgctgagtggtaaagataccgttcagcactggaactgg
acctcagacctgcccttgcaatgtgccactcactcggtgagcattcgatggcacattgac
tcgcctcatttctccggttacaaagagtggagtgactggagcccgctgaagaacatctcc
tggattcgtaatacagagactaatgtttttcctcaagacaaagtggtgctcgcaggctca
aacatgacaatttgttgtatgagtccaacgaaagtgctttcaggacagatcggcaatacc
cttcgtcctctcatccatctgtacgggcaaaccgttgcgatccatatcctgaacatcccc
gtttctgaaaacagtggcacaaacatcattttcatcacagacgacgatgtgtacggaacg
gtggtctttgcaggctatcctcccgatgttcctcagaagctgagctgtgagacacatgac
ttaaaagagattatatgtagctggaatccaggaaggataactggactggtgggcccacga
aatacagaatacaccctgtttgaaagcatttcaggaaaatcggcagtatttcacaggatt
gaaggacttacaaacgagacctaccggttaggcgtgcaaatgcatcccggccaagaaatc
cataacttcaccctgactggtcgcaatccactggggcaggcacagtcagcagtggtcatc
aatgtgactgagagagttgctcctcatgatccgacttcgttgaaagtgaaggacatcaat
tcaacagttgttacattttcttggtatttaccaggaaattttacaaagattaatctttta
tgtcaaattgaaatttgtaaagctaattccaagaaagaagtgaggaatgccacaatcaga
ggagccgaggattcaacttaccatgttgctgtagacaaattaaatccatacactgcatac
actttccgggttcgttgttcttccaagactttctggaagtggagcaggtggagtgatgag
aagcgacatctaaccacagaagccactccttcaaagggaccagacacttggagagagtgg
agttctgatggaaaaaatctaatcgtctactggaagcctttacctattaatgaagctaat
ggaaaaatactttcctacaatgtttcgtgttcattgaacgaggagacacagtcagttttg
gagatcttcgatcctcaacacagagcagagatacagcttagtaaaaatgactacatcatc
agtgtggtggcaagaaattctgctggctcatcaccaccttcgaaaatagctagtatggaa
atcccaaatgacgacatcacagtagagcaagcggtggggctaggaaacaggatcttcctc
acctggcgtcacgaccccaacatgacttgtgactacgtaattaaatggtgcaactcatct
cggtctgagccctgcctcctggactggagaaaggttccttcaaacagcacggagactgtc
atagagtctgatcagtttcagccaggagtaagatacaacttttacctctatgggtgcact
aaccagggataccaactgttacgttccataattggatacgtagaagaactggctcccatt
gtcgcgccaaatttcaccgtggaagatacgtcggcagactcgatattagtgaaatgggac
gacatccccgtggaagagctccgaggcttcctaagagggtatttattttactttcagaaa
ggagagagagatacgcccaagacgaggagcttggagccacatcattctgacatcaagcta
aagaacatcactgacatatcccagaagacactgaggattgctgaccttcagggtaaaacc
agttaccatctggtcctgcgagcctatacacatggtggtctgggcccagagaagagcatg
tttgtggtgaccaaggaaaactctgtgggattgattattgccatcctcatcccagtggct
gtggctgtcattgttggcgtggtaacgagcatcctttgctatcggaagcgagaatggatt
aaggaaacattctacccagatattcccaatccagaaaactgtaaggcgctacagtttcag
aagagcgtctgcgagggaagcaatgctcttaagacattggaaatgaacccctgtaccccg
aacaacgttgaagtcctggaatctcggtcgatagtccctaaaatagaagatacagaaata
atttccccagttgctgagcgtcctggggaaagatctgaggtggaccctgagaaccatgtg
gtcgtgtcttactgcccacccatcatcgaggaggaaataacgaaccccgcggccgatgaa
gtgggaggggcttcccaggtcgtgtacatcgatgtgcagtccatgtatcagccgcaagcc
aaagcagaggaagagcaggacgtggatcctgtggtggtggcaggctataagccacagatg
cgccttcccatcagccccgctgtggaagacacagcagcagaagatgaagagggtaagacc
gccggttacagacctcaggccaatgtaaacacttggaatttggtctctccagattccccg
aggtccacagacagcaacaacgaagttgtctcttttggaagtccgtgctccatcaattcc
aggcaattcttgattcctcctaaagacgaagactctcctaaatctaatggaggagggtgg
tcctttacaaacttcttccagaacaaaccaaatgactaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (27)   
   RefSeq(nuc) (7)   
   GenBank (10)   
   EMBL (10)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (8)   
All databases (80)   

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