KEGG   Mus musculus (house mouse): 16973
Entry
16973             CDS       T01002                                 
Symbol
Lrp5, BMND1, HBM, LR3, LRP7, OPPG, mKIAA4142
Name
(RefSeq) low density lipoprotein receptor-related protein 5
  KO
K03068  low density lipoprotein receptor-related protein 5/6
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04150  mTOR signaling pathway
mmu04310  Wnt signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05010  Alzheimer disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05200  Pathways in cancer
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    16973 (Lrp5)
   04150 mTOR signaling pathway
    16973 (Lrp5)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    16973 (Lrp5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16973 (Lrp5)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    16973 (Lrp5)
   05226 Gastric cancer
    16973 (Lrp5)
   05224 Breast cancer
    16973 (Lrp5)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    16973 (Lrp5)
   05022 Pathways of neurodegeneration - multiple diseases
    16973 (Lrp5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16973 (Lrp5)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    16973 (Lrp5)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition Ldl_recept_a DUF5050 SGL EGF Insulin_TMD
Other DBs
NCBI-GeneID: 16973
NCBI-ProteinID: NP_032539
MGI: 1278315
Ensembl: ENSMUSG00000024913
UniProt: Q91VN0
Position
19:complement(3634825..3736574)
AA seq 1614 aa
METAPTRAPPPPPPPLLLLVLYCSLVPAAASPLLLFANRRDVRLVDAGGVKLESTIVASG
LEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAAQNIVISGLVSPDGLACDWVGKK
LYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGM
DGSTRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPF
ALTLSGDTLYWTDWQTRSIHACNKWTGEQRKEILSALYSPMDIQVLSQERQPPFHTPCEE
DNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKTGAEEVLLLARRTDLRRISLDTPD
FTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGI
AVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGEN
PKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRKTLL
EDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNVAKVVG
TNPCADGNGGCSHLCFFTPRATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLE
TNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPE
GMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWG
GKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDTNMIESSNMLGQERMVI
ADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQD
GLNDCVHSNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIP
DDQLSPDLVLPLHGLRNVKAINYDPLDKFIYWVDGRQNIKRAKDDGTQPSMLTSPSQSLS
PDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDKPRAIAVNAERGYM
YFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDL
SGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGI
HAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSP
DQFACTTGEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDGEA
DCQDRSDEANCDAVCLPNQFRCTSGQCVLIKQQCDSFPDCADGSDELMCEINKPPSDDIP
AHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVGGAPHVPLNFIAPG
GSQHGPFPGIPCSKSVMSSMSLVGGRGSVPLYDRNHVTGASSSSSSSTKATLYPPILNPP
PSPATDPSLYNVDVFYSSGIPATARPYRPYVIRGMAPPTTPCSTDVCDSDYSTSRWKSSK
YYLDLNSDSDPYPPPPTPHSQYLSAEDSCPPSPGTERSYCHLFPPPPSPCTDSS
NT seq 4845 nt   +upstreamnt  +downstreamnt
atggaaacggcgccgacccgggcccctccgccgccgccgccgccgctgctgctgctggtg
ctgtactgcagcttggtccccgccgcggcctcaccgctcctgttgtttgccaaccgccgg
gatgtgcggctagtggatgccggcggagtgaagctggagtccaccattgtggccagtggc
ctggaggatgcagctgctgtagacttccagttctccaagggtgctgtgtactggacagat
gtgagcgaggaggccatcaaacagacctacctgaaccagactggagctgctgcacagaac
attgtcatctcgggcctcgtgtcacctgatggcctggcctgtgactgggttggcaagaag
ctgtactggacggactccgagaccaaccgcattgaggttgccaacctcaatgggacgtcc
cgtaaggttctcttctggcaggacctggaccagccaagggccattgccctggatcctgca
catgggtacatgtactggactgactggggggaagcaccccggatcgagcgggcagggatg
gatggcagtacccggaagatcattgtagactccgacatttactggcccaatgggctgacc
atcgacctggaggaacagaagctgtactgggccgatgccaagctcagcttcatccaccgt
gccaacctggacggctccttccggcagaaggtggtggagggcagcctcactcaccctttt
gccctgacactctctggggacacactctactggacagactggcagacccgctccatccac
gcctgcaacaagtggacaggggagcagaggaaggagatccttagtgctctgtactcaccc
atggacatccaagtgctgagccaggagcggcagcctcccttccacacaccatgcgaggag
gacaacggtggctgttcccacctgtgcctgctgtccccgagggagcctttctactcctgt
gcctgccccactggtgtgcagttgcaggacaatggcaagacgtgcaagacaggggctgag
gaagtgctgctgctggctcggaggacagacctgaggaggatctctctggacacccctgac
ttcacagacatagtgctgcaggtgggcgacatccggcatgccattgccattgactacgat
cccctggagggctacgtgtactggaccgacgatgaggtgcgggctatccgcagggcgtac
ctagatggctcaggtgcgcagacacttgtgaacactgagatcaatgaccccgatggcatt
gctgtggactgggtcgcccggaacctctactggacagatacaggcactgacagaattgag
gtgactcgcctcaacggcacctcccgaaagatcctggtatctgaggacctggacgaaccg
cgagccattgtgttgcaccctgtgatgggcctcatgtactggacagactggggggagaac
cccaaaatcgaatgcgccaacctagatgggagagatcggcatgtcctggtgaacacctcc
cttgggtggcccaacggactggccctggacctgcaggagggcaagctgtactggggggat
gccaaaactgataaaatcgaggtgatcaacatagatgggacaaagcggaagaccctgctt
gaggacaagctcccacatatttttgggttcacactgctgggggacttcatctactggacc
gactggcagagacgcagtattgaaagggtccacaaggtcaaggccagccgggatgtcatc
attgatcaactccccgacctgatgggactcaaagctgtgaatgtggccaaggttgtcgga
accaacccatgtgcggatggaaatggagggtgcagccatctgtgcttcttcaccccacgt
gccaccaagtgtggctgccccattggcctggagctgttgagtgacatgaagacctgcata
atccccgaggccttcctggtattcaccagcagagccaccatccacaggatctccctggag
actaacaacaacgatgtggctatcccactcacgggtgtcaaagaggcctctgcactggac
tttgatgtgtccaacaatcacatctactggactgatgtcagcctcaagacgatcagccga
gccttcatgaatgggagctcagtggagcacgtgattgagtttggcctcgactaccctgaa
ggaatggctgtggactggatgggcaagaacctctattgggcggacacagggaccaacagg
attgaggtggcccggctggatgggcagttccggcaggtgcttgtgtggagagaccttgac
aaccccaggtctctggctctggatcctactaaaggctacatctactggactgagtggggt
ggcaagccaaggattgtgcgggccttcatggatgggaccaattgtatgacactggtagac
aaggtgggccgggccaacgacctcaccattgattatgccgaccagcgactgtactggact
gacctggacaccaacatgattgagtcttccaacatgctgggtcaggagcgcatggtgata
gctgacgatctgccctacccgtttggcctgactcaatatagcgattacatctactggact
gactggaacctgcatagcattgaacgggcggacaagaccagtgggcggaaccgcaccctc
atccagggtcacctggacttcgtcatggacatcctggtgttccactcctcccgtcaggat
ggcctcaacgactgcgtgcacagcaatggccagtgtgggcagctgtgcctcgccatcccc
ggaggccaccgctgtggctgtgcttcacactacacgctggaccccagcagccgcaactgc
agcccgccctccaccttcttgctgttcagccagaaatttgccatcagccggatgatcccc
gatgaccagctcagcccggaccttgtcctaccccttcatgggctgaggaacgtcaaagcc
atcaactatgacccgctggacaagttcatctactgggtggacgggcgccagaacatcaag
agggccaaggacgacggtacccagccctccatgctgacctctcccagccaaagcctgagc
ccagacagacagccacacgacctcagcattgacatctacagccggacactgttctggacc
tgtgaggccaccaacactatcaatgtccaccggctggatggggatgccatgggagtggtg
cttcgaggggaccgtgacaagccaagggccattgctgtcaatgctgagcgagggtacatg
tactttaccaacatgcaggaccatgctgccaagatcgagcgagcctccctggatggcaca
gagcgggaggtcctcttcaccacaggcctcatccgtcccgtggcccttgtggtggacaat
gctctgggcaagctcttctgggtggatgccgacctaaagcgaatcgaaagctgtgacctc
tctggggccaaccgcctgaccctggaagatgccaacatcgtacagccagtaggtctgaca
gtgctgggcaggcacctctactggatcgaccgccagcagcagatgatcgagcgcgtggag
aagaccactggggacaagcggactagggttcagggccgtgtcacccacctgacaggcatc
catgccgtggaggaagtcagcctggaggagttctcagcccatccttgtgcccgagacaat
ggcggctgctcccacatctgtatcgccaagggtgatggaacaccgcgctgctcgtgccct
gtccacctggtgctcctgcagaacctgctgacttgtggtgagcctcctacctgctcccct
gatcagtttgcatgtaccactggtgagatcgactgcatccccggagcctggcgctgtgac
ggcttccctgagtgtgctgaccagagtgatgaagaaggctgcccagtgtgctccgcctct
cagttcccctgcgctcgaggccagtgtgtggacctgcggttacgctgcgacggtgaggcc
gactgccaggatcgctctgatgaagctaactgcgatgctgtctgtctgcccaatcagttc
cggtgcaccagcggccagtgtgtcctcatcaagcaacagtgtgactccttccccgactgt
gctgatgggtctgatgagctcatgtgtgaaatcaacaagccaccctctgatgacatccca
gcccacagcagtgccattgggcccgtcattggtatcatcctctccctcttcgtcatgggc
ggggtctactttgtctgccagcgtgtgatgtgccagcgctacacaggggccagtgggccc
tttccccacgagtatgttggtggagcccctcatgtgcctctcaacttcatagccccaggt
ggctcacagcacggtcccttcccaggcatcccgtgcagcaagtccgtgatgagctccatg
agcctggtgggggggcgcggcagtgtgcccctctatgaccggaatcacgtcactggggcc
tcatccagcagctcgtccagcacaaaggccacactatatccgccgatcctgaacccaccc
ccgtccccggccacagacccctctctctacaacgtggacgtgttttattcttcaggcatc
ccggccaccgctagaccatacaggccctacgtcattcgaggtatggcacccccaacaaca
ccgtgcagcacagatgtgtgtgacagtgactacagcaccagtcgctggaagagcagcaaa
tactacctggacttgaattcggactcagacccctacccccccccgcccaccccccacagc
cagtacctatctgcagaggacagctgcccaccctcaccaggcactgagaggagttactgc
cacctcttcccgcccccaccgtccccctgcacggactcgtcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (28)   
   RefSeq(nuc) (2)   
   GenBank (13)   
   EMBL (13)   
Protein domain (7)   
   Pfam (7)   
All databases (84)   

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