KEGG   Mus musculus (house mouse): 16987
Entry
16987             CDS       T01002                                 
Symbol
Lss, 2810025N20Rik, D10Ertd116e, Osc
Name
(RefSeq) lanosterol synthase
  KO
K01852  lanosterol synthase [EC:5.4.99.7]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00100  Steroid biosynthesis
mmu01100  Metabolic pathways
Module
mmu_M00101  Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    16987 (Lss)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.7  lanosterol synthase
     16987 (Lss)
SSDB
Motif
Pfam: SQHop_cyclase_C SQHop_cyclase_N Prenyltrans TED_complement
Other DBs
NCBI-GeneID: 16987
NCBI-ProteinID: NP_666118
MGI: 1336155
Ensembl: ENSMUSG00000033105
UniProt: Q8BLN5
Position
10:76367303..76392973
AA seq 733 aa
MTEGTCLRRRGGPYKTEPATDLTRWRLQNELGRQRWTYYQAEDDPGREQTGLEAHSLGLD
TRSYFTDLPKAQTAHEGALNGVTFYAKLQAEDGHWAGDYGGPLFLLPGLLITCHISHISL
PAGYREEMVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVALRILGIGPDDPDLVRARNV
LHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPEWVPAHPSTLWCHCRQVYLP
MSYCYATRLSASEDPLVQSLRQELYVQDYASIDWPAQRNNVSPDEMYTPHSWLLHVVYGL
LNLYERFHSTSLRKWAVQMLYEHIAADDCFTKCISIGPISKTINMLVRWSVDGPSSPAFQ
EHVSRIKDYLWLGLDGMKMQGTNGSQIWDTSFAIQALLEAGAHHRPEFLPCLQKAHEFLR
LSQVPENCPDYQKYYRHMRKGGFSFSTLDCGWIVADCTAEGLKAVLLLQNQCPSITEHIP
RERLCDAVDVLLSLRNADGGFATYEKKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQ
ALKHFHEHFPDYRAAEVRETLNQGLDFCRRKQRADGSWEGSWGVCFTYGTWFGLEAFACM
GHTYQDGAACAEVAQACNFLLSQQMADGGWGEDFESCEQRRYVQSARSQVHSTCWALMGL
MAVRHPDITAQERGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTSYRNIFPIWALGRF
SNLYPDNTLAGHI
NT seq 2202 nt   +upstreamnt  +downstreamnt
atgactgagggcacgtgtctgcggcgtcgtgggggaccctataaaactgagcccgccacc
gatctcacccgctggcggctccagaatgagttgggtcggcagagatggacttattatcaa
gcggaggacgaccctggtcgagagcagaccgggctagaggcccactctttgggactggac
acaagaagttatttcacggacttaccaaaagcgcaaacagcccatgagggggccctgaat
ggagtaaccttttatgccaagctgcaggctgaggatggacactgggctggtgattatggt
ggtccgctcttcctcttgccaggtctcctgattacctgtcacatatcacacatctctctg
ccagctggatacagagaggagatggtgcggtacctgcggtcagtgcagctccctgatggc
ggctggggcttgcacatcgaggacaagtccacagtgtttgggactgccctgaactatgtg
gctctcagaatcctgggtattgggcctgatgatcctgaccttgtgcgcgctcggaacgtc
cttcacaaaaaaggtggtgcggtggccatcccttcctgggggaagttctggctggctgtc
ctgaatgtttatagctgggaaggactcaacaccctattccctgagatgtggctgtttcct
gaatgggtaccagcgcacccctccactctctggtgtcactgccggcaggtctatctgccc
atgagttactgctacgccactcggctaagtgcctcagaggacccactggttcagagcctc
cgccaggaactctatgtgcaggattacgccagcatcgattggccagcgcagaggaacaac
gtgtcccccgatgagatgtacacgccacacagctggctgctgcatgtggtgtatggactc
ctcaacctgtatgaacgtttccatagcaccagcctgcggaagtgggccgtccagatgctg
tatgaacacattgcagctgatgactgtttcactaagtgcatcagcatcggcccgatctca
aagaccatcaacatgcttgttcgttggtcagtggatggaccatcctccccggccttccag
gagcacgtttctcggatcaaagattacctttggctgggccttgatggcatgaaaatgcag
ggcaccaatggatcacagatctgggacacttcatttgctatccaagcactgttagaggca
ggtgcacaccacagacctgagtttctgccctgcctgcagaaggctcacgagttcctgcgg
ctttcacaggttccagaaaactgtcctgactatcagaagtactatcgccatatgcgcaag
ggtggtttctccttcagcacactggactgtggctggatcgttgctgactgcacagccgag
ggtttgaaggctgtgctgctcctgcagaatcagtgtccgtccatcactgagcatatcccc
cgagagcggctgtgcgatgctgtggatgtgttactgagcttgaggaatgctgatggcggg
ttcgctacctatgagaagaagcgtgggggttacttgctggagctgctgaacccctcagag
gtctttggagacatcatgattgactacacgtatgtagagtgtacctccgctgtgatgcag
gcactgaagcatttccatgaacacttcccagactacagggcagcagaggtcagggagacc
ctcaatcaaggcctggacttctgccgaaggaagcagagagccgatggctcctgggagggc
tcctggggtgtttgtttcacctacggcacctggtttggcttggaagcgttcgcttgcatg
gggcatacctaccaagatggggctgcttgtgcagaagtagctcaggcctgcaacttcctc
ctgtcccagcagatggcggatggaggctggggagaggactttgaatcatgtgaacagcgg
cggtatgtgcagagtgctaggtcccaggtccatagcacctgctgggccctgatgggtttg
atggctgtcaggcatcccgacatcactgctcaggagagagggatcagatgtctgctaggg
aagcagttacccaatggagactggcctcaggagaacatctctggggtcttcaacaagtcc
tgtgccatcagctacacaagttacagaaacatcttccccatctgggccctgggccgcttc
tccaacctgtatcctgacaataccctcgccggccacatttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (43)   
   RefSeq(nuc) (9)   
   GenBank (17)   
   EMBL (17)   
Protein domain (4)   
   Pfam (4)   
All databases (84)   

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