KEGG   Mus musculus (house mouse): 170731
Entry
170731            CDS       T01002                                 
Symbol
Mfn2, D630023P19Rik, Fzo
Name
(RefSeq) mitofusin 2
  KO
K06030  mitofusin 2 [EC:3.6.5.-]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04137  Mitophagy - animal
mmu04621  NOD-like receptor signaling pathway
mmu05012  Parkinson disease
mmu05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    170731 (Mfn2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    170731 (Mfn2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    170731 (Mfn2)
   05022 Pathways of neurodegeneration - multiple diseases
    170731 (Mfn2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    170731 (Mfn2)
   03029 Mitochondrial biogenesis [BR:mmu03029]
    170731 (Mfn2)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    170731 (Mfn2)
  Other autophagy associated proteins
   ER-mitochondria tethering complex
    170731 (Mfn2)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Fission and Fusion factors
    170731 (Mfn2)
SSDB
Motif
Pfam: Fzo_mitofusin Dynamin_N MMR_HSR1
Other DBs
NCBI-GeneID: 170731
NCBI-ProteinID: NP_001272849
MGI: 2442230
Ensembl: ENSMUSG00000029020
UniProt: Q80U63
Position
4:complement(147958043..147989527)
AA seq 757 aa
MSLLFSRCNSIVTVKKDKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESASFLEDT
HRNTELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
VLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVS
VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQF
FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDR
IFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECISQSAVKTKFEQ
HTVRAKQIAEAVRLIMDSLHIAAQEQRVYCLEMREERQDRLRFIDKQLELLAQDYKLRIK
QITEEVERQVSTAMAEEIRRLSVLVDEYQMDFHPSPVVLKVYKNELHRHIEEGLGRNLSD
RCSTAIASSLQTMQQDMIDGLKPLLPVSMRNQIDMLVPRQCFSLSYDLNCDKLCADFQED
IEFHFSLGWTMLVNRFLGPKNSRRALLGYSDQVQRPLPLTPANPSMPPLPQSSLTQEELM
VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
FKRQFVEYASEKLQLIISYTGSNCSHQVQQELSGTFAHLCQQVDITRDNLEQEIAAMNKK
VEALDSLQSRAKLLRNKAGWLDSELNMFTHQYLQPSR
NT seq 2274 nt   +upstreamnt  +downstreamnt
atgtccctgctcttttctcgatgcaactccatcgtcaccgtcaagaaggataagcgacac
atggctgaagtgaatgcttcccctctcaagcactttgtcactgccaagaaaaagatcaat
ggaatctttgagcagctgggggcctacatccaagagagcgccagcttccttgaagacacc
cacaggaacacagaactggacccggttaccacggaagagcaggtcctggacgtcaaaggg
tacctgtccaaggtcaggggtatcagcgaagtgctggccaggcggcacatgaaggtggct
ttttttggccggacgagcaatgggaagagcaccgtgatcaatgccatgctctgggacaaa
gttctgccatctgggattggtcataccaccaattgcttcctgcgggttgggggcacagat
ggccatgaggccttcctcctcacagagggctcagaagagaagaagagtgtcaagactgtg
aaccaactggcccatgccctccatcaggacgagcagttgcatgcaggcagcatggtgagt
gtgatgtggcccaactccaagtgtccgctcctgaaggatgacctcgtgctgatggacagc
cctgggatcgatgttaccacggagctggacagctggattgataagttttgcctggatgct
gatgtgtttgtgctggtggccaactcagagtccacgctgatgcagacggagaagcagttc
ttccacaaagtgagtgaacgtctctcccggcccaacatcttcatcctgaacaaccgctgg
gatgcgtctgcctcggagcctgagtacatggaggaggtgcggcggcagcacatggagcgc
tgcaccagctttctggtggatgagctgggcgtggtggatcgagctcaggctggggaccgg
atcttcttcgtgtctgccaaggaggttctcagcgccagggtccagaaagcccagggcatg
ccagaaggaggcggcgctctcgcagaaggttttcaagtgaggatgtttgagtttcagaat
ttcgagaggcagtttgaggagtgcatttcccagtctgcagtaaagaccaaatttgagcag
cacacagtccgggccaagcagattgcagaggccgttcgtctcatcatggattccctgcac
atcgcagctcaggagcagcgggtttattgcctagaaatgcgggaagagcggcaagaccgg
ctgaggtttattgacaagcagctggagctcctggctcaagactacaagctgcgaattaag
cagattacggaggaagtggaaaggcaggtgtccacagccatggctgaagagatcaggcgc
ctctctgtgctagttgacgagtaccagatggacttccacccatccccagttgtcctcaag
gtttataagaacgagctgcaccgccatatagaggaaggtctgggccggaacctgtctgac
cgctgctccactgccattgccagttcactgcagactatgcagcaggacatgatagacggc
ttgaagccccttcttcctgtatctatgcggaatcagatagacatgctggtccctcgacag
tgtttctccctcagctatgacctgaattgtgacaagctgtgtgctgactttcaggaggac
atcgagttccacttctcccttggatggactatgctagtgaacaggttcctgggccccaag
aatagccgccgggccttgctaggctacagtgatcaggttcagcgtcctctccctctgaca
cctgccaaccccagcatgccccccttgccacagagctccctcacccaggaggagctcatg
gtctccatggttactggcctggcctctctgacgtctaggacctccatgggcattcttgtg
gtcggaggagtggtgtggaaggcagtgggctggagactcatcgccctctcctttggactg
tatggcctcctgtacgtctatgagcgactgacctggaccaccaaagccaaagagagggcc
ttcaagcgccagtttgtggaatacgccagtgagaagctacagctcatcatcagttacacc
ggctctaactgcagccaccaagtccagcaggaattgtctgggacatttgctcatctgtgc
cagcaagttgacatcacccgagataatctggagcaggaaattgctgccatgaacaagaaa
gtcgaggctctggattcacttcagagcagagccaaactgctcaggaataaagctggctgg
ttggacagcgaactcaacatgttcacacaccagtacctgcagcccagcagatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (79)   
   RefSeq(nuc) (13)   
   GenBank (33)   
   EMBL (33)   
Protein domain (3)   
   Pfam (3)   
All databases (117)   

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