KEGG   Mus musculus (house mouse): 17716
Entry
17716             CDS       T01002                                 
Symbol
ND1
Name
(RefSeq) NADH dehydrogenase subunit 1
  KO
K03878  NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00190  Oxidative phosphorylation
mmu01100  Metabolic pathways
mmu04714  Thermogenesis
mmu04723  Retrograde endocannabinoid signaling
mmu05010  Alzheimer disease
mmu05012  Parkinson disease
mmu05014  Amyotrophic lateral sclerosis
mmu05016  Huntington disease
mmu05020  Prion disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05208  Chemical carcinogenesis - reactive oxygen species
mmu05415  Diabetic cardiomyopathy
Module
mmu_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    17716 (ND1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    17716 (ND1)
  09159 Environmental adaptation
   04714 Thermogenesis
    17716 (ND1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    17716 (ND1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    17716 (ND1)
   05012 Parkinson disease
    17716 (ND1)
   05014 Amyotrophic lateral sclerosis
    17716 (ND1)
   05016 Huntington disease
    17716 (ND1)
   05020 Prion disease
    17716 (ND1)
   05022 Pathways of neurodegeneration - multiple diseases
    17716 (ND1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    17716 (ND1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:mmu03029]
    17716 (ND1)
Enzymes [BR:mmu01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     17716 (ND1)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    17716 (ND1)
SSDB
Motif
Pfam: NADHdh
Other DBs
NCBI-GeneID: 17716
NCBI-ProteinID: NP_904328
MGI: 101787
UniProt: P03888 Q4JFN6
Structure
Position
MT:2751..3707
AA seq 318 aa
MFFINILTLLVPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEP
MRPLTTSMSLFIIAPTLSLTLALSLWVPLPMPHPLINLNLGILFILATSSLSVYSILWSG
WASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMNGSYSLQTLITTQEHMWLLLPAWP
MAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTTI
IFLGPLYYINLPELYSTNFMMEALLLSSTFLWIRASYPRFRYDQLMHLLWKNFLPLTLAL
CMWHISLPIFTAGVPPYM
NT seq 957 nt   +upstreamnt  +downstreamnt
gtgttctttattaatatcctaacactcctcgtccccattctaatcgccatagccttccta
acattagtagaacgcaaaatcttagggtacatacaactacgaaaaggccctaacattgtt
ggtccatacggcattttacaaccatttgcagacgccataaaattatttataaaagaacca
atacgccctttaacaacctctatatccttatttattattgcacctaccctatcactcaca
ctagcattaagtctatgagttcccctaccaataccacacccattaattaatttaaaccta
gggattttatttattttagcaacatctagcctatcagtttactccattctatgatcagga
tgagcctcaaactccaaatactcactattcggagctttacgagccgtagcccaaacaatt
tcatatgaagtaaccatagctattatccttttatcagttctattaataaatggatcctac
tctctacaaacacttattacaacccaagaacacatatgattacttctgccagcctgaccc
atagccataatatgatttatctcaaccctagcagaaacaaaccgggcccccttcgacctg
acagaaggagaatcagaattagtatcagggtttaacgtagaatacgcagccggcccattc
gcgttattctttatagcagagtacactaacattattctaataaacgccctaacaactatt
atcttcctaggacccctatactatatcaatttaccagaactctactcaactaacttcata
atagaagctctactactatcatcaacattcctatggatccgagcatcttatccacgcttc
cgttacgatcaacttatacatcttctatgaaaaaactttctacccctaacactagcatta
tgtatgtgacatatttctttaccaatttttacagcgggagtaccaccatacatatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (15)   
   PDB (15)   
Protein domain (1)   
   Pfam (1)   
All databases (56)   

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