KEGG   Mus musculus (house mouse): 18218
Entry
18218             CDS       T01002                                 
Symbol
Dusp8, 5530400B01Rik, Nttp1
Name
(RefSeq) dual specificity phosphatase 8
  KO
K04459  dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04148  Efferocytosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    18218 (Dusp8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    18218 (Dusp8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    18218 (Dusp8)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     18218 (Dusp8)
    3.1.3.48  protein-tyrosine-phosphatase
     18218 (Dusp8)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    18218 (Dusp8)
SSDB
Motif
Pfam: DSPc Rhodanese Y_phosphatase SR-25
Other DBs
NCBI-GeneID: 18218
NCBI-ProteinID: NP_032774
MGI: 106626
Ensembl: ENSMUSG00000037887
UniProt: O09112 Q7TSZ9
Position
7:complement(141633224..141649799)
AA seq 663 aa
MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQ
QGKVTIAELIQPATRSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA
ILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD
LMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSC
QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL
KLLAALQTDGPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDA
PIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGE
APKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRRRPPASSPARSPAHGLGLNFGDT
ARQTPRHGLSALSAPGLPGPGQPAGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPGAVFS
AFGRVSAGAPGPGNSSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSSSSSSSSSSSSSSSS
DLRRRDVRTGWPEEPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVI
EVS
NT seq 1992 nt   +upstreamnt  +downstreamnt
atggctggggatcggctcccgaggaaggtgatggacgcaaagaaactggccagcctgctg
cgtggcgggcctgggggacccttggtcatcgacagccggtccttcgtggagtataacagc
tgccacgtgctgagctctgtgaatatctgctgttcaaagctggtgaagcggcgccttcag
cagggaaaagtgacaattgctgagcttatccagcctgctacacggagccaggtggatgcc
acagaaccacaggatgtagtggtgtatgaccagagcacacgagatgccagcgtgctggca
gcagacagcttcctgtccatcctgctcagcaagctggacggctgcttcgacagtgtggcc
atcctcacaggaggcttcgccaccttctcctcctgcttccctggcctctgtgagggcaag
cctgccactctaccgtccatgagcctctctcagccctgcctgcctgtgcccagtgttggc
ctgacccgaatcctgcctcacctctacctgggctctcagaaagatgtcttgaacaaggat
ctgatgacccaaaacggaataagctatgtcctcaatgccagcaactcctgccctaaaccg
gacttcatctgtgagagccgtttcatgcgtatccccatcaatgacaactactgtgaaaag
ctgctgccctggctggacaagtccatcgagtttattgataaagccaagctgtccagctgc
caagtcattgttcactgtctggctggcatctctcgctctgccaccattgccatcgcgtac
atcatgaaaaccatgggcatgtcttctgacgacgcatacaggtttgtgaaggatcggcgc
ccctccatctcgcccaacttcaacttcctgggccagttgctggagtatgagaggagtctg
aagctgctggctgccctgcagactgatggacctcacttggggacccctgagcccctcatg
ggcccggcagcaggcatcccactgccccggctgccaccatctacctcagagagcgctgcc
actgggagcgaggcagccaccgcagccagggagggcagcccaagtgctggaggggatgct
ccgatccccagcacagctccagccaccagcgcgctgcagcagggcctgcgtggcctgcac
ctctcctctgaccgcctccaggacaccaaccgcctcaagcgttccttttccctggacatc
aagtcggcctatgcacccagcaggaggcccgactttcccggcccacccgaccccggtgaa
gccccgaagctctgcaagctggacagcccgtctgggggcacactgggcctgccctcgccc
agcccagacagcccggactccgttccagagtgccgcccacgaccccgccggcgacgcccc
ccggctagttcgcctgcccgctcccccgcgcatggtctgggcctgaactttggagacacg
gcccggcagactccacggcacggcctctcggccctgtcggcgcccgggctgcctggccct
ggccagccggctggccccgggggctgggtgccgccactggactccccaggcacaccgtcg
cccgacggcccctggtgcttcagccccgagggcgcgcagggtccaggcgctgtgttctcc
gcctttggccgggtaagtgcaggcgcacctggacccggtaacagcagcagcagcggtggt
ggtggtggtggtggtggcggcggcggcggcggcggcggcggcggcggcagcagcagcagc
aacagcagcagcagcagcagcagcagcagcagcagcagcagcagtagtagtagtagtagt
gacctgcggaggcgggatgtgcggaccggctggcccgaggagcctgctgcagatgcacag
ttcaagaggcgcagctgccagatggagttcgaagagggcatggtggaggggcgggcacgt
ggcgaggagctggcagccctgggcaagcaaaccagcttctctggcagcgtggaggtcatc
gaagtatcgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (17)   
   RefSeq(nuc) (3)   
   GenBank (7)   
   EMBL (7)   
Protein domain (4)   
   Pfam (4)   
All databases (59)   

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