KEGG   Mus musculus (house mouse): 18453
Entry
18453             CDS       T01002                                 
Symbol
P4hb, ERp59, PDI, Pdia1, Thbp
Name
(RefSeq) prolyl 4-hydroxylase, beta polypeptide
  KO
K09580  protein disulfide-isomerase A1 [EC:5.3.4.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04141  Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    18453 (P4hb)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    18453 (P4hb)
   04131 Membrane trafficking [BR:mmu04131]
    18453 (P4hb)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    18453 (P4hb)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.4  Transposing S-S bonds
    5.3.4.1  protein disulfide-isomerase
     18453 (P4hb)
Chaperones and folding catalysts [BR:mmu03110]
 Protein folding catalysts
  Protein disulfide isomerase
   18453 (P4hb)
Membrane trafficking [BR:mmu04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   PDI family proteins
    18453 (P4hb)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   18453 (P4hb)
  Exosomal proteins of colorectal cancer cells
   18453 (P4hb)
  Exosomal proteins of bladder cancer cells
   18453 (P4hb)
SSDB
Motif
Pfam: Thioredoxin Thioredoxin_6 Thioredoxin_2 OST3_OST6 Thioredoxin_7 ERp29_N AhpC-TSA Thioredoxin_8 Redoxin HyaE
Other DBs
NCBI-GeneID: 18453
NCBI-ProteinID: NP_035162
MGI: 97464
Ensembl: ENSMUSG00000025130
UniProt: P09103
Position
11:complement(120451124..120464079)
AA seq 509 aa
MLSRALLCLALAWAARVGADALEEEDNVLVLKKSNFEEALAAHKYLLVEFYAPWCGHCKA
LAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTA
GREADDIVNWLKKRTGPAATTLSDTAAAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEA
IDDIPFGITSNSGVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQLPLVI
EFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSSFKRAAEGFKGKILFIFIDSDHTDN
QRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQ
EVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE
NIIIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGA
GDDEDLDLEEALEPDMEEDDDQKAVKDEL
NT seq 1530 nt   +upstreamnt  +downstreamnt
atgctgagccgtgctttgctgtgcctagccctggcctgggcggctagggtgggcgccgac
gccctggaggaggaggacaacgtcctggtgttgaagaagagcaacttcgaggaggcgctg
gcggcgcacaagtacctgctggtggagttctatgccccgtggtgtggccactgcaaagct
ctggctcccgagtatgccaaagctgccgcaaaactgaaggcagaaggctctgagattcga
ctagcaaaggtggatgccacagaagagtctgacctggctcagcagtatggtgtccgtggc
taccccacaatcaagttcttcaagaatggagacacagcctccccaaaggaatatacagct
ggcagggaagctgatgacattgtcaactggctgaagaaacgcacgggcccagcagctaca
accctgtctgacactgcagctgcagagtccttggtggactcaagcgaagtgacggtcatc
ggtttcttcaaggacgtagagtcagactctgccaagcagttcttgctggcagcagaggct
attgatgacataccttttggaatcacgtccaacagtggtgtgttctccaagtaccagctg
gacaaagatggggtggtcctctttaagaagtttgatgaaggccgcaacaactttgagggt
gagatcaccaaggagaagcttctagacttcatcaagcacaatcagctgcctttggtcatc
gagttcactgaacagacagctccgaagatttttggaggtgagatcaagacacacattctg
ctgttcctgcccaagagtgtatctgactatgacggcaagctgagcagcttcaagagagca
gccgagggcttcaagggcaagatcctatttatcttcatcgatagcgaccacactgataac
cagcgcatacttgagttctttggcctgaagaaggaggagtgtcccgctgtgcggcttatt
accctagaggaagagatgaccaagtacaaaccagagtcagatgagctgacggctgagaaa
atcacagagttttgccaccgcttcttagagggcaagatcaagccccacctgatgagccaa
gaagtgcctgaagactgggacaaacagccggtaaaagtactggttggggcgaactttgaa
gaggtcgcttttgatgagaaaaagaacgtgtttgttgaattctatgccccttggtgtggt
cactgcaagcagctagcccccatttgggataaactgggagagacatacaaggatcatgag
aatatcatcattgctaagatggactcaacagccaatgaggtggaagctgtcaaagtacat
agctttcccacactgaagttcttcccagcaagtgcagacagaacggtcattgattacaac
ggcgagcggacactggacggttttaagaaattcttggagagtggtggccaggatggagca
ggggacgatgaggacctcgacctagaagaagctttagagccagacatggaggaagacgac
gatcagaaagctgtgaaggatgaactgtag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (159)   
   RefSeq(nuc) (1)   
   GenBank (79)   
   EMBL (79)   
Protein domain (10)   
   Pfam (10)   
All databases (197)   

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