KEGG   Mus musculus (house mouse): 18478
Entry
18478             CDS       T01002                                 
Symbol
Pah
Name
(RefSeq) phenylalanine hydroxylase
  KO
K00500  phenylalanine-4-hydroxylase [EC:1.14.16.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00360  Phenylalanine metabolism
mmu00400  Phenylalanine, tyrosine and tryptophan biosynthesis
mmu00790  Folate biosynthesis
mmu01100  Metabolic pathways
mmu01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00360 Phenylalanine metabolism
    18478 (Pah)
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    18478 (Pah)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    18478 (Pah)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.1  phenylalanine 4-monooxygenase
     18478 (Pah)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT
Other DBs
NCBI-GeneID: 18478
NCBI-ProteinID: NP_032803
MGI: 97473
Ensembl: ENSMUSG00000020051
UniProt: P16331 Q3UEH8
Position
10:87357657..87419999
AA seq 453 aa
MAAVVLENGVLSRKLSDFGQETSYIEDNSNQNGAVSLIFSLKEEVGALAKVLRLFEENEI
NLTHIESRPSRLNKDEYEFFTYLDKRSKPVLGSIIKSLRNDIGATVHELSRDKEKNTVPW
FPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYT
EEERKTWGTVFRTLKALYKTHACYEHNHIFPLLEKYCGFREDNIPQLEDVSQFLQTCTGF
RLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFA
QFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKEGDSIKAYGAGLLSSFGELQYCLSD
KPKLLPLELEKTACQEYTVTEFQPLYYVAESFNDAKEKVRTFAATIPRPFSVRYDPYTQR
VEVLDNTQQLKILADSINSEVGILCHALQKIKS
NT seq 1362 nt   +upstreamnt  +downstreamnt
atggcagctgttgtcctggagaacggagtcctgagcagaaaactctcagactttgggcag
gaaacaagttacatcgaagacaactccaatcaaaatggtgctgtatctctgatattctca
ctcaaagaggaagttggtgccctggccaaggtcctgcgcttatttgaggagaatgagatc
aacctgacacacattgaatccagaccttcccgtttaaacaaagatgagtatgagtttttc
acctatctggataagcgtagcaagcccgtcctgggcagcatcatcaagagcctgaggaac
gacattggtgccactgtccatgagctttcccgagacaaggaaaagaacacagtgccctgg
ttcccaaggaccattcaggagctggacagattcgccaatcagattctcagctatggagcc
gaactggatgcagaccacccaggctttaaagatcctgtgtaccgggcgagacgaaagcag
tttgctgacattgcctacaactaccgccatgggcagcccattcctcgggtggaatacaca
gaggaggagaggaagacctggggaacggtgttcaggactctgaaggccttgtataaaaca
catgcctgctacgagcacaaccacatcttccctcttctggaaaagtactgcggtttccgt
gaagacaacatcccgcagctggaagatgtttctcagtttctgcagacttgtactggtttc
cgcctccgtcctgttgctggcttactgtcgtctcgagatttcttgggtggcctggccttc
cgagtcttccactgcacacagtacattaggcatggatctaagcccatgtacacacctgaa
cctgatatctgtcatgaactcttgggacatgtgcccttgttttcagatagaagctttgcc
cagttttctcaggaaattgggcttgcatcgctgggggcacctgatgagtacattgagaaa
ctggccacaatttactggtttactgtggagtttgggctttgcaaggaaggagattctata
aaggcatatggtgctgggctcttgtcatcctttggagaattacagtactgtttatcagac
aagccaaagctcctgcccctggagctagagaagacagcctgccaggagtatactgtcaca
gagttccagcctctgtactatgtggccgagagtttcaatgatgccaaggagaaagtgagg
acttttgctgccacaatcccccggcccttctccgttcgctatgacccctacactcaaagg
gttgaggtcctggacaatactcagcagttgaagattttagctgactccattaatagtgag
gttggaatcctttgccatgccctgcagaaaataaagtcatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
Protein domain (3)   
   Pfam (3)   
All databases (47)   

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