KEGG   Mus musculus (house mouse): 18548
Entry
18548             CDS       T01002                                 
Symbol
Pcsk1, Nec-1, Nec1, PC1, PC3, Phpp-1, SPC3
Name
(RefSeq) proprotein convertase subtilisin/kexin type 1
  KO
K01359  proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
Organism
mmu  Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    18548 (Pcsk1)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    18548 (Pcsk1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.93  proprotein convertase 1
     18548 (Pcsk1)
Peptidases and inhibitors [BR:mmu01002]
 Serine peptidases
  Family S8: subtilisin family
   18548 (Pcsk1)
Chaperones and folding catalysts [BR:mmu03110]
 Intramolecular chaperones
  Subtilisin family
   18548 (Pcsk1)
SSDB
Motif
Pfam: Peptidase_S8 P_proprotein S8_pro-domain Proho_convert Peptidase_S8_N OmpA_membrane
Other DBs
NCBI-GeneID: 18548
NCBI-ProteinID: NP_038656
MGI: 97511
Ensembl: ENSMUSG00000021587
UniProt: P63239 Q32MU0
Structure
Position
13:75237407..75282980
AA seq 753 aa
MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQ
IGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDL
FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYAN
YDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM
LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG
SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY
TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL
ASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALK
ANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERE
RDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEH
MKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQ
GTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSL
YSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN
NT seq 2262 nt   +upstreamnt  +downstreamnt
atggagcaaagaggttggactctgcagtgtactgctttcgccttcttttgcgtttggtgt
gcactaaacagtgtaaaagcaaagaggcagtttgttaatgaatgggcggcggagatcccc
ggagggcaagaagctgcctctgccatcgccgaagaactggggtatgaccttttgggtcag
attggatcacttgaaaatcactatttattcaaacacaaaagccatcctcggaggtcccga
agaagcgctcttcatatcactaagaggttatctgatgatgatcgtgtgacgtgggctgaa
caacagtatgaaaaagagagaagtaaacgttcagttcaaaaagactcagcattggatctc
ttcaatgatccaatgtggaatcagcagtggtacttgcaagataccagaatgactgcagct
ctgcccaagctggaccttcatgtaatacctgtttgggaaaagggtattactggcaaagga
gttgttattactgtactggatgatggcttggagtggaatcacacagacatttatgccaat
tatgatccagaggctagctatgattttaacgataatgatcatgatccatttccccgatat
gatctcacaaatgaaaacaaacatggaacaagatgtgcaggtgaaattgccatgcaagca
aataatcacaagtgtggggttggagttgcatataattccaaagttggaggcataagaatg
ctggatggcattgtaactgatgccattgaggctagttcaattggattcaaccctggccat
gtggatatttacagtgcaagctggggccctaatgatgatggaaaaactgtggaggggcct
ggcagactagcccagaaggcatttgaatatggtgtcaaacaggggagacaagggaaaggc
tccatctttgtctgggcttcagggaatgggggtcgtcagggagataactgtgactgtgat
ggctacacagacagcatttacaccatctctatcagcagtgcctcccagcaaggcctgtca
ccttggtatgcagagaagtgttcttccacattggctacctcctacagcagtggtgattac
acagaccagcgaataacaagcgctgacctgcacaatgactgcacagagacccacacaggc
acctcggcttcagcacccctggctgctggtatctttgctctggccttggaggcaaaccca
aatcttacctggagagatatgcagcatctggttgtctggacctctgagtacgacccattg
gccagtaacccaggttggaaaaagaatggggcaggcttgatggtgaacagccgatttgga
tttggcttgctaaatgccaaagctctggtggatttggctgatcctaggacctggagaaat
gtgcctgagaagaaagaatgtgttgtaaaagacaataactttgagcctagagccctgaaa
gctaatggagaagtaattgttgaaatcccaacaagagcttgtgaaggacaagaaaatgct
atcaagtctctggaacatgtgcaatttgaagcaacaattgaatattctcgtagaggagac
cttcatgtcacactcacttctgctgttggaaccagcactgtactgttggctgaaagggaa
agagatacatcccccaatggctttaagaattgggacttcatgtctgttcatacatgggga
gagaatcctgtaggcacctggacattgaaaattacagacatgtctggaagaatgcaaaat
gaaggaaggattgtgaactggaagttgattttgcatgggacatcttctcaaccagagcac
atgaagcagcctcgtgtgtacacatcctacaatacagtccagaatgacaggagaggagtg
gaaaagatggtgaatgttgtggagaagcggcccacacaaaagagcctgaatggcaatctc
ctggtacccaaaaactccagcagcagcaatgtggagggtagaagggatgagcaggtacaa
ggaactccttcaaaggccatgctgcgactcctacaaagtgcttttagcaagaatgcactt
tcaaaacaatcaccaaagaagtctccaagtgcaaagctcagcatcccttatgaaagtttc
tatgaagccttggaaaagctcaacaagccctccaagcttgaaggctctgaagacagtctg
tacagtgactatgttgatgtattctataacacaaaaccttataagcatagagatgacagg
ctgctgcaagctctcatggacatcctaaatgaggagaattaa

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (20)   
   RefSeq(nuc) (4)   
   GenBank (8)   
   EMBL (8)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (61)   

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