KEGG   Mus musculus (house mouse): 18578
Entry
18578             CDS       T01002                                 
Symbol
Pde4b, Dpde4, dunce
Name
(RefSeq) phosphodiesterase 4B, cAMP specific
  KO
K13293  cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04024  cAMP signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18578 (Pde4b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    18578 (Pde4b)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    18578 (Pde4b)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18578 (Pde4b)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     18578 (Pde4b)
SSDB
Motif
Pfam: PDEase_I PDE4_UCR DFP
Other DBs
NCBI-GeneID: 18578
NCBI-ProteinID: NP_001171451
MGI: 99557
Ensembl: ENSMUSG00000028525
UniProt: Q8VBU5 B1AWD0
Position
4:101944529..102464459
AA seq 564 aa
MKEQGGTVSGAASSRGGGDSAMASLQPLQPNYLSVCLFPEESYQKLAMETLEELDWCLDQ
LETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPT
QKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNI
FNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAA
DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE
SVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM
VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK
ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
QSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVID
PENRDSLEETDIDIATEDKSPIDT
NT seq 1695 nt   +upstreamnt  +downstreamnt
atgaaggagcaagggggcaccgtcagtggcgccgcgagcagccgaggtggaggagactcg
gctatggccagcctgcagccactgcagcctaactacctgtctgtgtgtttgtttccagaa
gaatcatatcagaaactagcaatggagacgctggaggaactagactggtgcctagaccag
ctagagaccatccagacctaccgctctgtcagcgagatggcttcaaacaagttcaaaagg
atgctgaaccgggagctgacacacctctcagagatgagcagatcagggaaccaggtgtct
gagtacatttcaaacacgttcttagacaagcagaacgatgtggaaatcccatctcccacg
cagaaggacagggagaagaagaagaagcagcagctcatgacccagataagtggagtgaag
aaactgatgcacagctcaagcctgaacaacacaagcatctcacgcttcggagtcaacacg
gaaaatgaggatcatctagccaaggagctggaagacctgaacaaatggggccttaacatc
ttcaatgtggctgggtactcacataatcggccccttacgtgcatcatgtatgcaatattc
caggaaagagaccttctgaagacgtttaaaatctcatctgacacctttgtaacctacatg
atgactttagaagaccattaccattctgatgtggcatatcacaacagcctgcatgctgct
gacgtggcccagtcaactcacgttctcctttctacgccggcactggatgctgtcttcaca
gacctggaaatcctggctgccatttttgcagctgccatccatgatgtcgatcatcctgga
gtctccaatcagtttctcatcaatacaaattctgaacttgctttgatgtataatgatgaa
tctgttctggaaaaccatcaccttgctgtgggattcaaattgctacaagaggaacactgc
gacatctttcagaatcttaccaagaagcaacgccagacactcaggaaaatggtgattgac
atggtgttggcaactgatatgtccaaacacatgagcctcctggcagaccttaaaacaatg
gtagaaaccaagaaggtgacaagctccggtgttctcctcctggacaactatactgaccgg
atacaggttcttcgcaacatggtacactgtgcagacctgagcaaccccaccaagtccttg
gaattgtatcggcaatggaccgatcgtatcatggaggagtttttccagcagggagacaaa
gaacgggagaggggaatggagattagcccaatgtgtgataagcacacagcttctgtggaa
aaatcccaggttggtttcattgactacattgtccatccactgtgggagacctgggcagac
ctggttcaaccggatgctcaagatattctggatacactagaagataacaggaactggtac
cagagtatgataccccagagcccttccccgccactggatgagaggagcagggactgccaa
ggcctgatggagaagtttcagtttgaactgacccttgaggaagaggattctgagggaccg
gaaaaggagggagaaggccacagctatttcagcagcacaaagacgctttgtgtgattgat
ccagagaacagggattctctggaagagactgacatagacattgcaacagaagacaagtct
ccgatcgacacataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (19)   
   UniProt (2)   
   RefSeq(pep) (17)   
DNA sequence (58)   
   RefSeq(nuc) (18)   
   GenBank (20)   
   EMBL (20)   
Protein domain (3)   
   Pfam (3)   
All databases (105)   

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