KEGG T01002: 18641

Mus musculus (house mouse): 18641

Entry

18641             CDS       T01002

Symbol

Pfkl, ATP-PFK, PFK-B, PFK-L

Name

(RefSeq) phosphofructokinase, liver, B-type

K00850

6-phosphofructokinase 1 [EC:2.7.1.11]

Organism

mmu Mus musculus (house mouse)

Pathway

mmu00010

Glycolysis / Gluconeogenesis

mmu00030

Pentose phosphate pathway

mmu00051

Fructose and mannose metabolism

mmu00052

Galactose metabolism

mmu01100

Metabolic pathways

mmu01200

Carbon metabolism

mmu01230

Biosynthesis of amino acids

mmu03018

RNA degradation

mmu04066

HIF-1 signaling pathway

mmu04152

AMPK signaling pathway

mmu04919

Thyroid hormone signaling pathway

mmu04922

Glucagon signaling pathway

mmu05230

Central carbon metabolism in cancer

Module

mmu_M00001

Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate

Brite

KEGG Orthology (KO) [BR:mmu00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    18641 (Pfkl)
   00030 Pentose phosphate pathway
    18641 (Pfkl)
   00051 Fructose and mannose metabolism
    18641 (Pfkl)
   00052 Galactose metabolism
    18641 (Pfkl)
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    18641 (Pfkl)
09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    18641 (Pfkl)
   04152 AMPK signaling pathway
    18641 (Pfkl)
09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    18641 (Pfkl)
   04919 Thyroid hormone signaling pathway
    18641 (Pfkl)
09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    18641 (Pfkl)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    18641 (Pfkl)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    18641 (Pfkl)
Enzymes [BR:mmu01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.11  6-phosphofructokinase
     18641 (Pfkl)
Protein phosphatases and associated proteins [BR:mmu01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     18641 (Pfkl)
Messenger RNA biogenesis [BR:mmu03019]
Prokaryotic type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Other RNA degradosome components
     18641 (Pfkl)

SSDB

Motif

Pfam:

PFK

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

MGI:

Ensembl:

UniProt:

Position

10:complement(77822781..77845641)

AA seq 780 aa
MATVDLEKLRMSGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE
GGENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDG
SLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDS
ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE
NFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQ
RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQK
AMDEERFDEAIQLRGRSFENNWKIYKLLAHQKVSKEKSNFSLAILNVGAPAAGMNAAVRS
AVRTGISEGHTVYIVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAI
VENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG
SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN
IHDLKANVEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGH
LQQGGAPTPFDRNYGTKLGVKAMLWVSEKLRDVYRKGRVFANAPDSACVIGLRKKVVAFS
PVTELKKETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF

NT seq 2343 nt +upstreamnt +downstreamnt
atggctaccgtggacctggagaaactgcggatgtcgggggctggcaaggccattggagtg
ctgaccagcggcggtgatgcgcaaggtatgaatgctgctgtcagggctgtgacccgtatg
ggcatatatgtgggggccaaagtcttcctcatctatgagggctacgagggccttgtggaa
ggaggcgagaacatcaagccagccaactggctcagcgtttccaatatcatccagctgggt
ggcaccattattggcagtgcccgctgtaaggccttcactacgagggaaggccgcctggct
gcagcctacaatctgctccaacacggcatcaccaacctgtgtgtcatcggtggcgacggc
agcctcacgggggccaacatcttccgcaacgagtggggcagcttgctggaggagctggtg
aaggaaggcaagatctcagagtccacagctcagaactacgcacacttgaccatcgccggt
ctggtgggctccatcgataacgacttctgtggcactgacatgaccattggcacagactca
gccctgcaccgcattatggaggtcattgacgccatcactaccactgcccaaagtcaccag
aggacctttgttttggaggtgatgggacggcactgcgggtacctggcgctggtgtctgcc
ctggcttccggggctgattggctattcattcctgaagcgccccctgaggatggctgggag
aacttcatgtgtgagaggctgggcgagactcggagccgaggctctcggctgaacatcatc
atcatcgcagagggtgccattgaccggcatggaaagcctatctcatccagctacgtgaag
gatctggtggttcagaggctgggcttcgatacacgagtgactgtgctgggtcatgtacag
cgaggagggacgccttcagccttcgaccgaatcctgagtagcaagatgggtatggaggcc
gtgatggcgctgctagaggccacgcctgacacgccggcctgtgtggtcagcctctccggg
aaccagtctgtgaggctacctctcatggagtgtgtgcaagtgacaaaggacgtgcagaag
gccatggacgaggagaggtttgacgaggccatccagctccgtggcaggagctttgagaac
aactggaaaatttacaagctccttgcccaccagaaggtgtctaaagagaagtccaacttc
tccctggccatcctgaatgtgggggctccagctgctggcatgaatgcagctgtgcgctcc
gcagtgcgcactggtatctccgagggacacacggtatacatcgtgcatgatggctttgag
ggtctggccaagggtcaggtgcaagaagtgggctggcatgatgtggcaggctggctggga
cgtggtggctcgatgctggggaccaagaggacactgcccaagccccacctggaggccatt
gtggagaatctccgcacctacaacatccacgccctgctggtgattggtggctttgaggcc
tacgagggtgtgctgcagctggtggaggcccgggggcgctacgaggaactctgcattgtc
atgtgtgtcatcccagccaccatcagcaacaatgtgcctggcactgacttcagcctgggc
tcagacacggctgtcaacgctgcaatggagagttgtgatcgcatcaagcagtcagcctca
gggacaaagcggcgtgtgttcattgtagagaccatggggggctactgtggctacctggct
actgtgaccggcattgctgtgggtgccgatgctgcctacgtctttgaggaccctttcaac
atccatgacttaaaggccaatgtggagcatatgacagagaagatgaagacagacatccag
aggggactggtgctccggaacgagaagtgtcacgaacactacaccacagagttcctatac
aacctgtactcctcagaaggcaggggcgtgtttgactgcaggaccaatgtgctgggccac
ttgcagcagggtggtgctccaacccctttcgaccggaactatgggaccaaactgggggtg
aaggccatgttgtgggtgtctgagaagctacgtgatgtctaccgtaaagggcgggtgttt
gccaatgctccagactcagcctgtgtgatcggcctgcggaagaaggtagtggccttcagt
ccggtcacagaactcaagaaagagactgattttgagcaccgcatgccccgggagcagtgg
tggctgaatctgcggctgatgctgaagatgctggcacactaccgcatcagcatggcagac
tatgtgtctggggagctggagcacgtcacacgccgcaccttgagcatagacaagggtttc
tga

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