KEGG   Mus musculus (house mouse): 18670
Entry
18670             CDS       T01002                                 
Symbol
Abcb4, Mdr2, Pgy-2, Pgy2, mdr-2
Name
(RefSeq) ATP-binding cassette, sub-family B member 4
  KO
K05659  ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:7.6.2.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu02010  ABC transporters
mmu04976  Bile secretion
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    18670 (Abcb4)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    18670 (Abcb4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    18670 (Abcb4)
Enzymes [BR:mmu01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     18670 (Abcb4)
Transporters [BR:mmu02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    18670 (Abcb4)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_22 Rad17 AAA_16 RsgA_GTPase Zeta_toxin AAA_5 AAA AAA_29 G-alpha AAA_7 AAA_14 AAA_15 SbcC_Walker_B nSTAND1 DUF815 NTPase_1 Peptidase_MA_2
Other DBs
NCBI-GeneID: 18670
NCBI-ProteinID: NP_032856
MGI: 97569
Ensembl: ENSMUSG00000042476
UniProt: P21440
Position
5:8943614..9009226
AA seq 1276 aa
MDLEAARNGTARRLDGDFELGSISNQGREKKKKVNLIGLLTLFRYSDWQDKLFMFLGTLM
AIAHGSGLPLMMIVFGEMTDKFVDNTGNFSLPVNFSLSMLNPGRILEEEMTRYAYYYSGL
GGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILRQEMGWFDIKGTTELNTRLTDDVSK
ISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSD
KELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAISANISMGI
AFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGA
AYVIFDIIDNNPKIDSFSERGHKPDNIKGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQ
TVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLFS
TTIAENIRYGRGNVTMDEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAI
ARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGF
EDGVIVEQGSHSELMKKEGIYFRLVNMQTAGSQILSEEFEVELSDEKAAGDVAPNGWKAR
IFRNSTKKSLKSPHQNRLDEETNELDANVPPVSFLKVLKLNKTEWPYFVVGTVCAIANGA
LQPAFSIILSEMIAIFGPGDDAVKQQKCNMFSLVFLGLGVLSFFTFFLQGFTFGKAGEIL
TTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNTANLG
TGIIISFIYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEMEAAGKIATEAIENI
RTVVSLTQERKFESMYVEKLHGPYRNSVRKAHIYGITFSISQAFMYFSYAGCFRFGSYLI
VNGHMRFKDVILVFSAIVLGAVALGHASSFAPDYAKAKLSAAYLFSLFERQPLIDSYSGE
GLWPDKFEGSVTFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLE
RFYDPMAGSVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVPHDE
IVRAAKEANIHPFIETLPQKYNTRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATS
ALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQK
GIYFSMVNIQAGTQNL
NT seq 3831 nt   +upstreamnt  +downstreamnt
atggatcttgaggcagcgagaaacggaacagcacggcgcctggacggcgactttgaacta
ggcagcatcagcaaccaaggcagagaaaagaagaagaaagtgaatttaattggcctgttg
acactgttccgatactctgactggcaggataaattgtttatgttcctgggcaccctcatg
gccatagctcatggatcaggtcttcccctcatgatgatagtctttggagaaatgacagat
aagtttgtagataatactgggaacttttccttgccagtgaatttttcattgtcaatgcta
aatccaggaagaattttggaagaagaaatgactagatatgcatactactattcgggacta
ggtggtggagttcttgtggctgcctatatccaagtctcattctggactttggcagctggc
cgacaaataaagaaaatcaggcaaaaattttttcatgccatcctccgacaagaaatgggc
tggtttgacatcaagggcaccactgaactcaacacacgtctaacagatgacgtctccaaa
atcagtgaaggaattggtgacaaggttggaatgttctttcaagcaatagccacgtttttt
gcaggattcatagtggggttcatcagaggatggaagctcaccctcgtgatcatggccatc
agccccatcctggggctctctacagctgtttgggcaaagatactctcaacatttagtgac
aaagagctagctgcatatgcaaaagcaggtgccgtggctgaagaggctctgggagccatc
aggaccgtgatagctttcgggggccagaacaaagagctagaaaggtatcagaaacattta
gaaaatgccaaaaagattggaattaaaaaggctatctcagccaacatctccatgggtatt
gctttcttgttaatatatgcatcctatgcactggccttctggtatggatccactctggtt
atatcaaaagaatatacaattggaaatgcaatgacagtcttcttctcaatcctcatcggg
gctttcagtgtggggcaggctgccccctgtattgatgctttcgctaatgcaagaggagca
gcctatgtgatctttgacattattgataataatcctaaaattgacagtttttcagagaga
ggacacaaaccagacaacatcaaaggaaatttggagttcagtgatgttcatttttcctat
ccatctcgggctaatatcaagatcttgaagggcctcaacctgaaggtgaagagtggacag
acagtggctctggttggcaacagcggctgtggaaaaagcacaactgtccagctgctgcag
aggctctacgaccccacagagggtaagattagcatcgatgggcaggatatcaggaacttt
aacgtcaggtgtctaagggaaatcattggtgtggtaagtcaagagcccgtgctgttctct
actacgatcgctgaaaatatccgctatggccgtgggaatgtaacgatggatgagattgag
aaagccgtcaaagaggccaatgcctatgacttcatcatgaaactgccccagaaatttgac
accctggttggtgatagaggggcgcagctgagtgggggacagaaacagagaatcgccatt
gcccgggccctggtccgcaaccccaagatcctcctgctggacgaggccacctcagccctg
gacactgaaagtgaagctgaggtgcaggccgcactggataaggccagagaaggccgaacc
accattgtgatagctcaccgattgtctaccatccggaacgcagatgtcatcgctgggttt
gaggatggagtcattgtggaacaaggaagtcacagtgagctgatgaagaaggaagggatc
tacttcagactcgttaacatgcagacagcaggaagccagatcctgtcagaagaatttgaa
gttgagctaagtgacgaaaaggctgctggagatgtggccccaaatggctggaaagcacgc
atatttaggaattctacaaagaaaagtcttaaaagtccacatcagaataggctggatgaa
gaaaccaatgaacttgatgcaaacgtgccaccagtgtcttttctgaaggtcttaaaactg
aataaaacagagtggccctactttgtggtgggaacagtctgtgccattgccaatggagcc
ctccagccggctttctccatcatcctgtctgagatgatagctatctttggccctggggat
gacgcagtgaagcagcaaaagtgtaacatgttctccctggtcttcttgggcctaggagtc
ctctccttctttactttcttccttcagggcttcacgtttgggaaagctggagagatcctc
accacaaggctccggtccatggcctttaaagcgatgctaaggcaggacatgagctggttt
gatgatcataaaaacagtactggagcactttctacaagactcgccacagatgctgcgcaa
gtccaaggagccacgggaaccaggttggctttaattgcacagaacacagccaaccttgga
accggtattattatatcatttatttacggttggcaactgacacttctgctgttatcggtt
gttccattcattgctgtagcaggaattgttgaaatgaaaatgttggctggcaatgccaag
agagataaaaaggaaatggaagctgctggaaagattgcaacagaggcaatagaaaatatt
cgaactgttgtatccttgacccaagaaagaaaatttgagtcaatgtatgttgaaaaattg
catggaccttacaggaattcggtgcggaaggcacacatctacggcatcacttttagcatc
tcccaagcattcatgtatttttcttatgctggctgttttcgatttggttcttacctaatt
gtgaatggacatatgcgcttcaaagatgtcattctggtcttttctgcaattgtgcttggc
gcggtggctctaggacacgccagctcatttgctccggactatgcaaaagccaagctgtct
gcagcatacttgttcagcctgtttgaaagacaacctctgattgacagctacagtggagaa
gggctgtggcctgataagtttgaaggaagcgtgacatttaatgaagtcgtgttcaactat
cccacccgggccaacgtgccagtgcttcaggggctgagccttgaggtgaagaagggccag
acgctggccctggtgggcagcagtggctgcgggaagagcacagtggtccagctgctcgag
cgcttctatgaccccatggctggatcagtgctcttagatggtcaagaagcaaagaaactc
aatgtccagtggctccgagctcaactgggcattgtgtcccaggaacccattctctttgac
tgcagcatcgcagagaacatcgcctatggagacaacagccgggtcgtgcctcatgatgag
attgtgagggcagccaaggaggccaacatccaccccttcatcgagacgctgccccaaaaa
tataacacaagagtaggagacaaggggacgcagctctctgggggccagaagcagaggatt
gccatcgcccgagccctcatcagacagcctcgggtcctactgctggatgaagccacgtca
gctctggatactgagagtgaaaaggttgtccaggaagcactggacaaagccagggaaggc
cgcacctgcattgtgatcgctcaccgcctgtccaccatccagaacgcggacttgatcgtg
gtgattgagaacggcaaggtcaaggagcacggcacccaccagcagctgctggcgcagaag
ggcatctatttctcaatggtcaacatccaggccggcacacagaacttatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (23)   
   RefSeq(nuc) (5)   
   GenBank (9)   
   EMBL (9)   
Protein domain (21)   
   Pfam (21)   
All databases (80)   

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