KEGG   Mus musculus (house mouse): 18704
Entry
18704             CDS       T01002                                 
Symbol
Pik3c2a, Cpk-m, PI3KC2
Name
(RefSeq) phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
  KO
K00923  phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu01100  Metabolic pathways
mmu04070  Phosphatidylinositol signaling system
mmu05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    18704 (Pik3c2a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    18704 (Pik3c2a)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    18704 (Pik3c2a)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.154  phosphatidylinositol-4-phosphate 3-kinase
     18704 (Pik3c2a)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_C2 PI3K_rbd C2 PX DUF4135
Other DBs
NCBI-GeneID: 18704
NCBI-ProteinID: NP_035213
MGI: 1203729
Ensembl: ENSMUSG00000030660
UniProt: Q61194 F8VPL2
Structure
Position
7:complement(115936500..116042693)
AA seq 1686 aa
MAQISNNSEFKQCSSSHPEPIRTKDVNKAEALQMEAEALAKLQKDRQMTDSPRGFELSSS
TRQRTQGFNKQDYDLMVFPELDSQKRAVDIDVEKLTQAELEKILLDDNFETRKPPALPVT
PVLSPSFSTQLYLRPSGQRGQWPPGLCGPSTYTLPSTYPSAYSKQATFQNGFSPRMPTFP
STESVYLRLPGQSPYFSYPLTPATPFHPQGSLPVYRPLVSPDMAKLFEKIASTSEFLKNG
KARTDLEIANSKASVCNLQISPKSEDINKFDWLDLDPLSKPKVDYVEVLEHEEEKKDPVL
LAEDPWDAVLLEERSPSCHLERKVNGKSLSGATVTRSQSLIIRTAQFTKAQGQVSQKDPN
GTSSLPTGSSLLQEFEVQNDEVAAFCQSIMKLKTKFPYTDHCTNPGYLLSPVTVQRNMCG
ENASVKVSIEIEGLQLPVTFTCDVSSTVEIIIMQALCWVHDDLNQVDVGSYILKVCGQEE
VLQNNHCLGSHEHIQNCRKWDTEIKLQLLTLSAMCQNLARTAEDDEAPVDLNKYLYQIEK
PYKEVMTRHPVEELLDSYHYQVELALQTENQHRAVDQVIKAVRKICSALDGVETPSVTEA
VKKLKRAVNLPRNKSADVTSLSGSDTRKNSTKGSLNPENPVQVSMDHLTTAIYDLLRLHA
NSSRCSTGCPRGSRNIKEAWTATEQLQFTVYAAHGISSNWVSNYEKYYLICSLSHNGKDL
FKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFGVLNQSSGSSPDSNK
QRKGPEALGKVSLTLFDFKRFLTCGTKLLYLWTSSHTNSIPGAIPKKSYVMERIVLQVDF
PSPAFDIIYTSPQIDRNIIQQDKLETLESDIKGKLLDIIHRDSSFGLSKEDKVFLWENRY
YCLKHPNCLPKILASAPNWKWANLAKTYSLLHQWPPLCPLAALELLDAKFADQEVRSLAV
SWMEAISDDELADLLPQFVQALKYEIYLNSSLVRFLLSRALGNIQIAHSLYWLLKDALHD
THFGSRYEHVLGALLSVGGKGLREELSKQMKLVQLLGGVAEKVRQASGSTRQVVLQKSME
RVQSFFLRNKCRLPLKPSLVAKELNIKSCSFFSSNAMPLKVTMVNADPLGEEINVMFKVG
EDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFRCLSTGRDRGMVELVPASDTLRKIQVEY
GVTGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRS
TGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAY
NLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLG
SIATKFNFFIHNLAQLRFSGLPSNDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDK
HYIYVVRILREGHLEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVA
AKRKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRDEKAEGIARSAGAVPFSPTLGQIG
GAVKLSVSYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDTHKTSKRKTKISRKTRN
PTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGITLPLKDFNLSKETVKWYQL
TAATYL
NT seq 5061 nt   +upstreamnt  +downstreamnt
atggctcagatttccaacaacagtgaatttaaacaatgttcatcttcacatccagaacca
ataagaaccaaagatgtgaacaaagcagaagcgttacagatggaagcagaagccttagca
aaactgcagaaggatagacaaatgactgacagcccaagaggctttgagctgtctagcagc
actagacaaagaacacaaggttttaacaaacaggattatgatctcatggtgtttcctgag
ttggattcccaaaaaagagcagtagatattgatgtagaaaagctcacccaggctgaactt
gagaagatattgctggacgacaattttgaaactagaaaacctcctgcattgccagttact
cctgttctgagcccttcgttctcaacacagctgtatcttagacctagtggtcaaagaggc
cagtggccccctggattatgcgggccttccacgtacactttaccttctacttatccttca
gcatacagtaaacaggccacattccagaatggcttcagtccaaggatgcccacttttcca
tcaacagagtctgtatatttaagacttcctggacagtctccatatttttcatatcctttg
acacctgccacaccatttcatccacaaggaagtttaccagtctatcggccactagtcagt
cctgacatggcaaaactatttgaaaaaatagcaagtacctcagaatttttaaaaaatggg
aaagcaaggactgatttggagatagcaaactcgaaagcttcagtctgcaatctacagata
tctccaaagtctgaagacatcaataagtttgattggttagacttggatcctctgagtaag
cctaaggtagactatgtggaggtgttagaacatgaagaagagaagaaggatccagttttg
ctagcagaggatccttgggatgctgttcttcttgaagagagatcgccaagttgtcaccta
gaaagaaaggtgaatggaaaatccctttctggggcaactgtaacaagaagccagtcttta
atcattcggacagctcaatttacaaaagcccagggccaagtatctcagaaagacccaaat
gggaccagtagtttgccaactggaagttctcttctacaagaatttgaagtacagaatgac
gaggtggcagctttttgtcaatccattatgaaattgaagaccaaatttccatatactgat
cactgcacaaatccaggctatttgttaagtccagtgacagtgcaaagaaacatgtgtggg
gagaatgccagtgtgaaggtctccattgaaattgaagggcttcaactaccagttactttt
acatgtgatgtgagttctactgtagaaataattataatgcaagccctttgctgggtacat
gatgacttgaatcaagtggatgttggcagctacattctgaaagtttgtggtcaagaggag
gttctacagaataatcattgccttggaagtcacgaacatattcaaaattgtcgaaaatgg
gacacagagattaaattacagctcttgaccttgagtgcaatgtgccagaatctggctcga
acagcagaagatgatgaagcacctgtggatttaaacaaatacttgtatcaaatagaaaaa
ccttataaagaagtcatgacaagacaccctgttgaagagctcttagattcctatcactac
caagtagaactggctcttcaaactgaaaaccagcaccgagctgttgatcaagtgattaaa
gcagtaagaaaaatttgtagtgctttagatggggtggagaccccctccgttacagaagca
gtgaagaagttaaagcgagcagttaaccttccaaggaataaaagtgctgatgtgacttca
ttatctggaagtgacacaaggaagaactcaactaaggggtcactgaatcctgaaaatcct
gttcaagtaagcatggatcacctaacaacagcgatttatgatcttctcaggctccatgca
aattctagtaggtgttctacaggctgtccccgagggagcaggaacatcaaggaagcatgg
actgcaacggagcagctccagttcactgtctatgccgcacacggaatttccagtaactgg
gtatcaaattatgaaaaatactacttgatatgttccctgtctcacaatgggaaggatctt
tttaagcctattcagtcaaagaaggttggcacgtacaagaatttcttctatcttattaaa
tgggatgaactaatcatttttcctatccagatatcgcagttgccattagaatcagttctt
catcttactctgtttggagttttaaatcagagcagtggaagttcccctgattctaataaa
cagagaaaggggccagaagctctgggcaaagtttctttaactctatttgattttaaacgg
tttttaacatgtggaactaaacttctctacctttggacttcatcacatacaaattctatt
cctggagcaatccccaaaaaaagctatgtcatggaaagaattgtgctacaggttgatttt
ccttctcctgcgtttgacattatttatacatctcctcaaattgatagaaacattatacag
caagacaagttggaaacactggagagtgatataaaggggaaacttctggatattattcac
agagattcatcatttggactttctaaagaagataaggtctttttgtgggaaaaccgctat
tattgcctaaaacatccaaattgtcttccgaagatattagcaagtgctccaaactggaag
tgggctaatcttgccaaaacttactcattgctgcatcagtggccgccattgtgcccacta
gctgcattggagctccttgatgcaaaatttgctgatcaggaggtgcgatcgcttgctgtg
agctggatggaggccattagtgatgatgagctagcagatctgctcccacagttcgtacag
gctttgaaatatgaaatttatttgaatagttcactagtgcgcttccttctgtccagggca
ttgggaaacatccagatagcacacagtttgtattggcttctcaaggatgctttgcatgat
acacactttggaagcagatatgaacatgtgttgggtgctctcctctctgtaggaggaaaa
ggactcagagaagagctttctaagcagatgaaacttgtacagcttttaggaggagtggca
gaaaaagtaaggcaggctagtggatcaacaagacaggttgtcctccaaaagagtatggaa
cgggtacagtccttttttctgagaaataaatgccgtcttcctctcaaaccaagtctagtg
gcaaaagaactaaatattaagtcatgttcgttcttcagttctaatgctatgcctctgaaa
gtcacaatggtgaatgctgaccctctgggggaagaaattaatgtcatgtttaaggttggt
gaagatcttcggcaagatatgttagctttacagatgataaagattatggataagatctgg
cttaaagagggactggatctgaggatggtgatattcagatgcctgtcaactggccgagat
cgaggcatggtggagctagttcctgcttcagataccctcaggaaaatccaagtggaatat
ggtgtaacaggatcctttaaagataaaccacttgctgagtggctgaggaaatacaatcct
tctgaagaagaatatgaaaaggcttctgagaactttatctactcttgtgctgggtgctgt
gtagccacctatgttttaggcatttgtgatcggcacaatgacaatataatgcttcgaagc
acaggacacatgttccacattgactttggaaagtttttgggccatgcacagatgtttggt
agcttcaaaagggaccgagctccttttgtgcttacctctgacatggcgtatgtcattaat
ggaggtgaaaagcccaccattcgtttccagttgtttgtggacctctgctgtcaagcctac
aacttgataagaaagcaaacaaacctctttcttaaccttctctcactgatgattccttca
ggattgccagaactcacaagtattcaggatctgaaatatgttagagatgcacttcagccc
caaactacagatgctgaagctactattttctttactaggctgattgagtcaagtttggga
agcattgccacaaagtttaatttcttcattcataaccttgctcagctacgtttttctggc
cttccttctaatgatgagcccatcctttcattctcaccgaaaacatactcctttagacaa
gatggccggatcaaggaagtctctgttttcacatatcataagaaatacaacccagataaa
cactatatttatgtggttcgaattctaagagaaggacaccttgaaccatcatttgtattc
cggacatttgatgaatttcaggaacttcacaataagctcagtattatttttcctctttgg
aaattacctggctttcctaataggatggttcttggaagaacacacataaaagatgttgca
gccaagaggaaaattgaattaaacagttatttacagagtttgatgaatgcatcaacagat
gtagcagagtgtgatcttgtttgtacttttttccaccctttacttcgtgatgagaaagct
gaaggaatagctaggtctgcaggtgcagttcccttcagcccaactctgggccaaatagga
ggagcagtgaagttatctgtttcttaccgaaatggcaccctcttcatcatggtgatgcac
atcaaagatcttgtgactgaagatggggctgacccaaatccctatgtcaaaacatacctg
cttccagatacccacaaaacgtcaaaacgtaaaaccaaaatttcacgtaaaactaggaac
ccaacattcaatgaaatgcttgtatatagtggatacagcaaagaaactctgaggcagaga
gaacttcaactgagtgtactcagtgcagaatcactgcgggagaatttcttcttgggtgga
ataaccctgccactgaaagatttcaacttgagcaaagagacagttaagtggtatcagctg
actgcggcaacgtatctataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (38)   
   RefSeq(nuc) (4)   
   GenBank (17)   
   EMBL (17)   
3D Structure (8)   
   PDB (8)   
Protein domain (7)   
   Pfam (7)   
All databases (107)   

Download RDF
DBGET integrated database retrieval system