| Entry |
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| Symbol |
Pomc, ACTH, BE, Beta-LPH, Clip, Gamma-LPH, Npp, Pomc-1, Pomc1, alpha-MSH, alphaMSH, beta-MSH, gamma-MSH
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| Name |
(RefSeq) pro-opiomelanocortin-alpha
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| KO |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu04080 | Neuroactive ligand-receptor interaction |
| mmu04920 | Adipocytokine signaling pathway |
| mmu04925 | Aldosterone synthesis and secretion |
| mmu04927 | Cortisol synthesis and secretion |
|
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
18976 (Pomc)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
18976 (Pomc)
09150 Organismal Systems
09152 Endocrine system
04920 Adipocytokine signaling pathway
18976 (Pomc)
04915 Estrogen signaling pathway
18976 (Pomc)
04916 Melanogenesis
18976 (Pomc)
04925 Aldosterone synthesis and secretion
18976 (Pomc)
04927 Cortisol synthesis and secretion
18976 (Pomc)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
18976 (Pomc)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:mmu04052]
18976 (Pomc)
Cytokines and neuropeptides [BR:mmu04052]
Neuropeptides
Neuropeptides (GPCR binding)
18976 (Pomc)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
12:4004945..4010643
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| AA seq |
235 aa
MPRFCYSRSGALLLALLLQTSIDVWSWCLESSQCQDLTTESNLLACIRACKLDLSLETPV
FPGNGDEQPLTENPRKYVMGHFRWDRFGPRNSSSAGSAAQRRAEEEAVWGDGSPEPSPRE
GKRSYSMEHFRWGKPVGKKRRPVKVYPNVAENESAEAFPLEFKRELEGERPLGLEQVLES
DAEKDDGPYRVEHFRWSNPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ |
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| NT seq |
708 nt +upstreamnt +downstreamnt
atgccgagattctgctacagtcgctcaggggccctgttgctggccctcctgcttcagacc
tccatagatgtgtggagctggtgcctggagagcagccagtgccaggacctcaccacggag
agcaacctgctggcttgcatccgggcttgcaaactcgacctctcgctggagacgcccgtg
tttcctggcaacggagatgaacagcccctgactgaaaacccccggaagtacgtcatgggt
cacttccgctgggaccgcttcggccccaggaacagcagcagtgctggcagcgcggcgcag
aggcgtgcggaggaagaggcggtgtggggagatggcagtccagagccgagtccacgcgag
ggcaagcgctcctactccatggagcacttccgctggggcaagccggtgggcaagaaacgg
cgcccggtgaaggtgtaccccaacgttgctgagaacgagtcggcggaggcctttccccta
gagttcaagagggagctggaaggcgagcggccattaggcttggagcaggtcctggagtcc
gacgcggagaaggacgacgggccctaccgggtggagcacttccgctggagcaacccgccc
aaggacaagcgttacggtggcttcatgacctccgagaagagccagacgcccctggtgacg
ctcttcaagaacgccatcatcaagaacgcgcacaagaagggccagtga |
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