KEGG   Mus musculus (house mouse): 19246
Entry
19246             CDS       T01002                                 
Symbol
Ptpn1, PTP-1B, PTP-HA2, PTP1B
Name
(RefSeq) protein tyrosine phosphatase, non-receptor type 1
  KO
K05696  tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04520  Adherens junction
mmu04910  Insulin signaling pathway
mmu04931  Insulin resistance
mmu05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    19246 (Ptpn1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    19246 (Ptpn1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    19246 (Ptpn1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    19246 (Ptpn1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    19246 (Ptpn1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     19246 (Ptpn1)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    19246 (Ptpn1)
SSDB
Motif
Pfam: Y_phosphatase DSPc Y_phosphatase3 PTPlike_phytase Tudor_5
Other DBs
NCBI-GeneID: 19246
NCBI-ProteinID: NP_035331
MGI: 97805
Ensembl: ENSMUSG00000027540
UniProt: P35821 Q3TZW9
Position
2:167772670..167821305
AA seq 432 aa
MEMEKEFEEIDKAGNWAAIYQDIRHEASDFPCKVAKLPKNKNRNRYRDVSPFDHSRIKLH
QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLK
CAQYWPQQEEKEMVFDDTGLKLTLISEDVKSYYTVRQLELENLTTKETREILHFHYTTWP
DFGVPESPASFLNFLFKVRESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKD
PSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSREDLD
LPPEHVPPPPRPPKRTLEPHNGKCKELFSSHQWVSEETCGDEDSLAREEGRAQSSAMHSV
SSMSPDTEVRRRMVGGGLQSAQASVPTEEELSSTEEEHKAHWPSHWKPFLVNVCMATLLA
TGAYLCYRVCFH
NT seq 1299 nt   +upstreamnt  +downstreamnt
atggagatggagaaggagttcgaggagatcgacaaggctgggaactgggcggctatttac
caggacattcgacatgaagccagcgacttcccatgcaaagtcgcgaagcttcctaagaac
aaaaaccggaacaggtaccgagatgtcagcccttttgaccacagtcggattaaattgcac
caggaagataatgactatatcaatgccagcttgataaaaatggaagaagcccagaggagc
tatattctcacccagggccctttaccaaacacatgtgggcacttctgggagatggtgtgg
gagcagaagagcaggggcgtggtcatgctcaaccgcatcatggagaaaggctcgttaaaa
tgtgcccagtattggccacagcaagaagaaaaggagatggtctttgatgacacaggtttg
aagttgacactaatctctgaagatgtcaagtcatattacacagtacgacagttggagttg
gaaaacctgactaccaaggagactcgagagatcctgcatttccactacaccacatggcct
gactttggagtccccgagtcaccggcttctttcctcaatttccttttcaaagtccgagag
tcaggctcactcagcctggagcatggccccattgtggtccactgcagcgccggcatcggg
aggtcagggaccttctgtctggctgacacctgcctcttactgatggacaagaggaaagac
ccatcttccgtggacatcaagaaagtactgctggagatgcgcaggttccgcatggggctc
atccagactgccgaccagctgcgcttctcctacctggctgtcatcgagggcgccaagttc
atcatgggcgactcgtcagtgcaggatcagtggaaggagctctcccgggaggatctagac
cttccacccgagcacgtgcccccacctccccggccacccaaacgcacactggagcctcac
aacgggaagtgcaaggagctcttctccagccaccagtgggtgagcgaggagacctgtggg
gatgaagacagcctggccagagaggaaggcagagcccagtcaagtgccatgcacagcgtg
agcagcatgagtccagacactgaagttaggagacggatggtgggtggaggtcttcaaagt
gctcaggcgtctgtccccaccgaggaagagctgtcctccactgaggaggaacacaaggca
cattggccaagtcactggaagcccttcctggtcaatgtgtgcatggccacgctcctggcc
accggcgcgtacttgtgctaccgggtgtgttttcactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (90)   
   RefSeq(nuc) (4)   
   GenBank (43)   
   EMBL (43)   
Protein domain (5)   
   Pfam (5)   
All databases (126)   

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