KEGG   Mus musculus (house mouse): 19360
Entry
19360             CDS       T01002                                 
Symbol
Rad50, Mrell, Rad50l
Name
(RefSeq) RAD50 double strand break repair protein
  KO
K10866  DNA repair protein RAD50 [EC:3.6.-.-]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03440  Homologous recombination
mmu03450  Non-homologous end-joining
mmu04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    19360 (Rad50)
   03450 Non-homologous end-joining
    19360 (Rad50)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    19360 (Rad50)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mmu03032]
    19360 (Rad50)
   03400 DNA repair and recombination proteins [BR:mmu03400]
    19360 (Rad50)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Replication Termination Factors
   MRN complex
    19360 (Rad50)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     19360 (Rad50)
    BRCA1-C complex
     19360 (Rad50)
   NHEJ (non-homologous end-joining)
    MRX complex
     19360 (Rad50)
SSDB
Motif
Pfam: AAA_23 Rad50_zn_hook AAA_21 SbcC_Walker_B SMC_N Crescentin AAA_15 AAA_29 DUF2703
Other DBs
NCBI-GeneID: 19360
NCBI-ProteinID: NP_033038
MGI: 109292
Ensembl: ENSMUSG00000020380
UniProt: Q5SV02
Position
11:complement(53540346..53598146)
AA seq 1312 aa
MSRIEKMSILGVRSFGIEDKDKQIISFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG
TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGEMVAVHRSMLCSQKNKKTEFKTLEGVITR
MKHGEKVSLSSKCAEIDREMISCLGVSKSVLNNVIFCHQEDSNWPLSEGKALKQKFDEIF
SATRYIKALDTLRQVRQTQGQKVKECQTELKYLKQNKEKACEIRDQITSKEAQLASSQEI
VRSYEDELEPLKNRLKEIEHNLSKIMKLDNEIKALESRKKQMEKDNSELEQKMEKVFQGT
DEQLNDLYHNHQRTVREKERRLVDCQRELEKLNKEARLLNQEKAELLVEQGRLQLQADRH
QEHIRARDSLIQSLATHLELDGFERGPFSERQIKNFHELVKERQEREAKTASQLLSDLTD
KEALKQRQLDELRDRKSGLGRTIELKTEILTKKQSELRHVRSELQQLEGSSDRILELDQE
LTKAERELSKAEKNSSIETLKAEVMSLQNEKADLDRSLRKLDQEMEQLNHHTTTRTQMEM
LTKDKTDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKE
LASAEQNKNHINNELKKKEEQLSSYEDKLFDVCGSQDLESDLGRLKEEIEKSSKQRAMLA
GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELK
KKERRRDEMLGLVPVRQSIIDLKEKEIPELRNRLQSVNRDIQRLKNDIEEQETLLGTIMP
EEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGVDLDRTVQQVNQEKQEKQHRLD
TVTSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIATNLQRRQQMEEQSVELSTEVQS
LNREIKDAKEQISPLETALEKLQQEKEELIHRKHTSNKMAQDKINDIKEKVKNIHGYMKD
IENYIQDGKDDYKKQKETELNGVAVQLNECEKHREKINKDMGTMRQDIDTQKIQERWLQD
NLTLRKRRDELKEVEEERKQHLKEMGQMQVLQMKNEHQKLEENIDTIKRNHSLALGRQKG
YEDEILHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKM
EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGR
CSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDRENIESLAHALVEIIKSRSQQR
NFQLLVITHDEDFVELLGRSEYVEKFYRVKKNMDQCSEIVKCSISSLGSYVH
NT seq 3939 nt   +upstreamnt  +downstreamnt
atgtcccggatcgaaaagatgagcattctgggcgtgcgaagttttgggatagaggataaa
gataagcagattatctctttcttcagccccctcacaattttggttggacccaatggggcg
gggaagacgaccatcattgaatgtctaaagtatatttgtactggagatttccctcctgga
accaaaggaaatacatttgttcatgatcccaaggttgctcaagaaacagacgtgcgggcc
cagattcgcctgcagtttcgagatgtgaatggagagatggtagctgtgcacaggtctatg
ctttgcagtcagaaaaataaaaaaacagaatttaaaaccttggaaggagtcattactaga
atgaagcatggtgaaaaagtcagtctcagctccaaatgtgcagaaatcgacagagaaatg
ataagttgtcttggggtttccaagtctgtgctaaacaatgttattttctgtcaccaagaa
gactccaactggcctttaagtgaaggaaaggctttgaagcaaaaatttgatgagattttt
tcggcaacaaggtacattaaagccttagatacacttcgacaggtgcgtcagacacagggt
cagaaagtaaaagagtgtcaaacggaattgaaatatctgaagcaaaataaggagaaagcg
tgtgagatccgagatcagattacgagtaaggaagcccagttagcgtcttcgcaggaaatt
gtcaggtcctacgaggatgagcttgagccattgaagaatcgcctgaaagagattgaacac
aacctgtctaaaataatgaaacttgataatgaaattaaagccttggagagccgaaagaaa
caaatggagaaagataacagtgaattagaacagaaaatggaaaaggtttttcaagggact
gatgagcagctaaatgacttgtatcacaatcaccagagaacagtaagggagaaagaaagg
cgcctggtagactgccagcgagaactggagaagctgaataaagaagcacggctcctcaac
caggaaaaagcagagctgcttgtggagcagggtcgtctacagctacaggcagatcgccat
caagagcacatccgagccagagactcattaattcagtctttggcaacacatcttgaattg
gatggttttgagcgtggaccattcagtgaaagacagattaaaaattttcatgaacttgtg
aaagagagacaggaaagagaagctaaaactgccagccagctcttgagcgacctgacagac
aaagaagctctgaagcagaggcagcttgatgagctgagggacaggaagagcggactgggg
aggacgattgagctgaagacagagatcctcacgaagaagcagagcgagctgcggcacgtg
aggagtgagctgcagcagctggagggctcctccgacaggattctggaactggaccaggag
ctcacgaaagctgaacgtgaattaagcaaggccgagaaaaatagcagcatagaaacccta
aaagcagaggtaatgagcctccaaaatgagaaagctgacctggacaggagcttgcgaaag
ctggaccaggagatggagcagttaaaccatcatacaacaacccgcacacagatggagatg
ctcaccaaagacaaaactgacaaagatgaacagatcagaaaaataaagtctaggcacagt
gatgaactaacttcactgttggggtactttcctaacaaaaaacagcttgaagactggctt
cattctaaatccaaagaaattaatcagaccagggacagacttgccaaactgaacaaagag
ctagcttcagctgaacaaaataaaaatcatataaataatgagctaaagaaaaaggaagaa
cagttgtccagttatgaagataagctatttgatgtttgtggtagccaagatttggaaagt
gatttgggcagacttaaagaagaaattgaaaagtcctcaaagcagcgagccatgctggca
ggagccacagcagtttactcccagttcattacgcagctgacagatgaaaaccagtcctgc
tgcccagtctgtcagagagtatttcagacagaggctgagttacaggaagtcatcagcgac
ttgcagtccaagctgaggcttgctccagataaactcaagtcaacagaatcggaactgaag
aaaaaagagcggcgccgtgatgaaatgcttgggcttgtgcccgtgaggcaaagcataatt
gatttgaaggaaaaggaaataccagaattaagaaaccgactacagagtgtcaatagagac
atacagcgcctaaagaatgacatagaagagcaggaaacactcttgggtacaataatgcct
gaagaagaaagtgctaaagtgtgcctgacagatgttacaatcatggagaggttccagatg
gagctgaaagatgttgaaaggaaaattgcacagcaggcagctaagctgcagggagtagac
ttggaccggactgtccagcaggttaaccaggaaaagcaggaaaagcagcacaggctggat
acagttaccagtaagattgaattgaaccgtaagcttatacaggaccagcaggaacaaatc
caacacctgaaaagtaaaacaaatgagctgaagtcagagaagctgcagatagccaccaat
ttgcaacggcgccagcaaatggaggagcagagtgtggaattatccactgaagtccagtct
ttaaacagagaaataaaggatgctaaagaacaaataagccctttggagacagcattggaa
aagttgcagcaggaaaaagaagaattaatccacagaaaacatacaagtaacaaaatggct
caggataaaattaatgatatcaaagagaaagttaaaaatattcatggttacatgaaagac
atagagaattatattcaagatggaaaagatgactacaagaagcaaaaagaaactgaactt
aatggagttgctgttcaactaaatgaatgtgagaaacacagagaaaagataaataaagac
atgggaaccatgaggcaagacatcgacacacagaagatacaggaaaggtggctacaggat
aaccttacactaagaaaaaggagagatgaactaaaagaagtggaagaagaacgaaaacaa
cacttgaaggagatgggacaaatgcaagttttacaaatgaaaaatgagcatcagaagttg
gaagagaacatagacactataaagagaaatcacagtttggcattggggcgtcagaaaggc
tatgaagacgaaattcttcactttaaaaaggagctccgagaacctcagttccgggatgcc
gaggaaaagtacagagaaatgatgatcgtcatgaggaccacagagctggtgaacaaggac
ctcgacatctactacaagactcttgaccaagcaattatgaaatttcacagtatgaaaatg
gaagaaatcaacaaaattattcgtgatctttggcggagtacctatcgtgggcaagatatt
gaatacatagaaattcgatctgatgctgatgaaaatgtatcggcttctgataaaaggcga
aattacaactaccgagtggtgatgctgaagggggacacagccttggacatgcgtggacga
tgcagtgctggacagaaggtgctagcgtctctcatcatccgactggccctggcggaaacc
ttctgtctgaactgtggcatccttgccttggatgagccgacaacaaatctcgaccgagaa
aacattgagtctcttgcacatgctttggttgagatcataaaaagtcgctcacagcagcgc
aacttccaacttctggtaatcactcacgatgaagattttgtggagctcttagggcgatct
gagtatgtggagaaattctacagggtgaagaagaacatggaccagtgctcagagattgtc
aagtgcagcatcagctccctgggttcttatgttcactaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (45)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (36)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (9)   
   Pfam (9)   
All databases (80)   

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