KEGG   Mus musculus (house mouse): 19702
Entry
19702             CDS       T01002                                 
Symbol
Ren2, Ren, Ren-2, Ren-B, Rn-2, Rnr
Name
(RefSeq) renin 2 tandem duplication of Ren1
  KO
K01380  renin [EC:3.4.23.15]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04614  Renin-angiotensin system
mmu04924  Renin secretion
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    19702 (Ren2)
   04614 Renin-angiotensin system
    19702 (Ren2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    19702 (Ren2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    19702 (Ren2)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.15  renin
     19702 (Ren2)
Peptidases and inhibitors [BR:mmu01002]
 Aspartic peptidases
  Family A1: pepsin family
   19702 (Ren2)
SSDB
Motif
Pfam: Asp TAXi_N A1_Propeptide PE-PGRS_C TAXi_C Asp_protease_2 DUF6086
Other DBs
NCBI-GeneID: 19702
NCBI-ProteinID: NP_112470
MGI: 97899
UniProt: P00796
Structure
Position
1 E4; 1
AA seq 424 aa
MVCIKEGSGGLGYTALRKPWLNQMDRRRMPLWALLLLWSPCTFSLPTGTTFERIPLKKMP
SVREILEERGVDMTRLSAEWDVFTKRSSLTDLISPVVLTNYLNSQYYGEIGIGTPPQTFK
VIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGDDFTIHYGSGRVKGFLSQ
DSVTVGGITVTQTFGEVTELPLIPFMLAQFDGVLGMGFPAQAVGGVTPVFDHILSQGVLK
EKVFSVYYNRGPHLLGGEVVLGGSDPEHYQGDFHYVSLSKTDSWQITMKGVSVGSSTLLC
EEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKRLHEYVVSCSQVPTLPDISFNLGGRA
YTLSSTDYVLQYPNRRDKLCTVALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGF
ALAR
NT seq 1275 nt   +upstreamnt  +downstreamnt
atggtgtgtataaaagaaggctcagggggtctgggctacacagctcttagaaagccttgg
ctgaaccagatggacaggaggaggatgcctctctgggcactcttgttgctctggagtcct
tgcaccttcagtctcccaacgggcaccacctttgaacgaatcccactcaagaaaatgccc
tctgtccgggaaatcctggaggagcggggagtggacatgaccaggctcagtgctgaatgg
gacgtattcacaaagaggtcttccttgactgatcttatctcccccgtggtcctcaccaac
tacctgaatagccagtactatggcgagatcggcattggtaccccaccccagaccttcaaa
gtcatctttgacacgggctccgccaacctctgggtgccctccaccaagtgcagccgcctc
taccttgcttgtgggattcacagcctctatgagtcctctgactcctccagctacatggag
aatggagacgacttcaccatccactacggatcagggagagtcaaaggtttcctcagccag
gactcggtgactgtgggtggaatcactgtgacacagacctttggagaggtcaccgagctg
cccctgatccctttcatgctggcccagtttgacggggttctaggcatgggctttcccgct
caggccgtcggcggggtcacccctgtctttgaccacattctctcccagggggtgctgaag
gagaaagtgttctctgtctactacaacaggggtccccacctgctggggggcgaggtggtg
ctaggaggcagcgacccggagcattaccaaggcgattttcactatgtgagcctcagcaag
actgattcctggcagatcacaatgaagggggtgtctgtggggtcttccaccctactgtgt
gaagaaggctgtgaggtagtggtggacactggttcatcctttatctcggctcctacgagc
tccctgaagttgatcatgcaagccctgggagccaaggagaagagactacatgaatatgtt
gtgagctgtagccaggtgcccaccctccccgacatctccttcaacctgggaggcagggcc
tacacactcagcagtacggactacgtgctacagtatcccaacaggagagacaagctgtgc
acagtggctctccatgccatggacatcccaccacccactgggcctgtctgggtcctgggt
gccaccttcatccgcaagttctatacagagtttgatcggcataacaatcgcattggattc
gccttggcccgctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (59)   

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