KEGG   Mus musculus (house mouse): 19704
Entry
19704             CDS       T01002                                 
Symbol
Upf1, B430202H16Rik, NORF1, PNORF-1, Rent1, Upflp
Name
(RefSeq) UPF1 RNA helicase and ATPase
  KO
K14326  regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03013  Nucleocytoplasmic transport
mmu03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    19704 (Upf1)
   03015 mRNA surveillance pathway
    19704 (Upf1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    19704 (Upf1)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.3  DNA 5'-3' helicase
     19704 (Upf1)
    5.6.2.5  RNA 5'-3' helicase
     19704 (Upf1)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Surveillance complex
     19704 (Upf1)
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     19704 (Upf1)
SSDB
Motif
Pfam: UPF1_Zn_bind AAA_12 AAA_11 UPF1_1B_dom AAA_30 AAA_19 ResIII SLFN-g3_helicase ATPase nSTAND3 Helicase_RecD DEAD AAA_16 UvrD-helicase SRP54 UvrD_C_2 AAA_22
Other DBs
NCBI-GeneID: 19704
NCBI-ProteinID: NP_001116301
MGI: 107995
Ensembl: ENSMUSG00000058301
UniProt: Q9EPU0
Position
8:complement(70784143..70806418)
AA seq 1124 aa
MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGAGGPGGA
GAGGAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPVHACSY
CGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYN
CGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKI
PSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAYQYQNI
FGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAFFTLPKTDSGNEDLVIIWLRDM
RLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQVDFV
WKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVVIKCQLPKRFTAQGLPDLNHS
QVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKI
HQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKR
YRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA
KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSN
IFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVE
KITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREK
DFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKE
QKALVEGPLNNLRESLMQFSKPRKLVNTVNPGARFMTTAMYDAREAIIPGSVYDRSSQGR
PSNMYFQTHDQISMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKTK
TGRGGRQKNRFGLPGPSQTTLPNSQASQDVASQPFSQGALTQGYVSMSQPSQMSQPGLSQ
PELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY
NT seq 3375 nt   +upstreamnt  +downstreamnt
atgagtgtggaggcgtacggccccagctcgcaaacactcaccttcttggacactgaggag
gccgagctgctcggcgccgacacccagggctccgagttcgaattcaccgacttcaccctt
cccagccagacgcagacgccccccggcggccccggcggcgcgggaggcccgggcggagcg
ggcgcaggcggcgcggccggccagctcgacgcacaagttggaccagagggcatcttgcaa
aatggggctgtggatgacagtgtggccaagaccagccagctgctagctgagctgaacttc
gaggaagatgaagaggacacatactacactaaggacctcccagtccacgcctgcagttac
tgtggaatccatgatcctgcctgcgtggtttactgtaataccagcaagaagtggttctgc
aatggccgaggaaatacttctggcagccacattgtgaatcacctcgtgagggcaaaatgc
aaggaagtgacgctgcacaaggacgggcctctgggcgagaccgtgctggagtgctacaac
tgtggctgccgcaacgtcttcctgctgggcttcatccctgcgaaggccgactctgtggtg
gtgctgttgtgcaggcagccctgtgccagccagagcagcctgaaggacatcaactgggac
agctcacagtggcagcccctaatccaggaccggtgctttctgtcatggctggtcaagatt
ccctctgagcaggagcagctgcgagcacggcagatcacggcacagcagatcaacaagctg
gaagagctctggaaggaaaatccttcagccactctggaggacctggagaagccaggcgta
gacgaggagccacagcacgtgctcctgcgttacgaggatgcttaccagtaccagaacatc
ttcgggccactggtcaagctggaggctgactatgacaagaagttgaaggagtcacagact
caagataacatcacggtcaggtgggacctgggccttaacaagaagagaatcgccttcttc
actttgcccaagactgactctggtaatgaggatttagtcataatttggttaagagacatg
cggctcatgcagggtgatgagatctgtctgcggtacaaaggggatctggcgcccctgtgg
aaggggattggccacgtcatcaaggttcctgataattatggtgatgagattgctattgag
ctccgcagcagcgtgggtgcccctgtggaagtgacccacaacttccaagtggattttgtg
tggaagtcaacctcttttgataggatgcagagtgcactgaagaccttcgctgtggacgag
acctctgtgtcagggtatatttaccacaagctgctgggccacgaggtggaggatgtggtc
atcaagtgccagctgccaaagcgcttcacagctcaggggctccctgacctcaaccactct
caggtgtatgctgtgaagaccgtgctgcagagaccactcagcctcatccagggccctcca
ggcacaggcaagactgtgacatcagccactattgtctaccaccttgctcggcagggcaat
gggcctgtactggtttgtgctccaagtaacatcgctgtggaccagctcacagagaagatc
caccagacaggactgaaggtcgtacgcctctgtgccaagagccgtgaggccattgactcc
ccagtgtccttcctggctttgcacaaccagatcaggaacatggacagcatgcctgagctg
cagaagctgcagcagctaaaggatgagacaggcgagctgtcatctgcagatgagaagcgg
taccgggcgcttaagcgcacagctgagagagaacttctcatgaatgcagatgtcatatgc
tgcacatgtgtgggtgctggtgacccgaggctggccaagatgcagttccgttccatcctc
attgacgagagcacccaggccactgagcctgagtgcatggtgcctgtagtccttggggcc
aagcagctaatcctcgtcggtgaccactgccagctgggcccagtggtgatgtgcaagaag
gcagccaaggccggactgtcacaatcgctcttcgagcgcttggtggtgctgggcatccgg
cccatccgcctgcaggtgcaataccgcatgcaccctgcactcagcgcctttccgtccaac
atcttctacgagggctcattgcagaatggcgtcactgcagcggatcgtgtcaaaaaaggc
tttgacttccagtggccacaacctgacaagcctatgttcttctacgtgacgcagggccag
gaggagattgccagctctggcacatcctacctcaacaggacggaggcagccaatgtggag
aagataactacgaagctgttgaaggcaggtgcaaagcctgaccagatcggcatcatcacc
ccctacgagggccagcgctcttacttggtgcagtacatgcagttcagcggctccctgcac
acaaagctctaccaggaagtggaaattgccagtgtggacgccttccagggccgggagaag
gacttcatcattctgtcctgcgtgcgcgccaatgaacatcagggcattgggttcctaaac
gacccccggcgtctgaatgtggctctcaccagagcaagatatggcgtgatcattgtgggt
aacccaaaggccctgtcgaagcagcccctgtggaatcacctgctgagctactacaaggaa
cagaaggcgctagtggaagggccgctcaacaacctacgtgagagcctcatgcagttcagc
aagcctcgcaaacttgtcaacactgtcaacccgggtgcccgcttcatgactactgccatg
tacgatgcccgtgaggccatcatccccgggtctgtctatgaccgcagcagccagggccgg
ccctcgaacatgtacttccagacccatgaccagattagtatgatcagcgcaggccccagc
cacgtggctgccatgaacatccctattcccttcaacttggtcatgcctcccatgccgcca
cctggctacttcggacaggccaacgggccggcagctggtcggggcaccccaaaaaccaag
actggccgtgggggccgccagaagaaccgctttgggcttcctgggcccagccagaccacc
cttcccaacagccaggccagccaggacgtggcctcccagcccttttcacagggtgccctc
acacagggttacgtgtccatgagccagccctctcagatgagccagcctggcctctcccag
ccagaactgtcccaggacagctacctcggtgatgagtttaaatcacagattgacgtggca
ctctcacaagactccacataccagggagagcgggcataccagcacggcggggtcaccggg
ctgtcccagtactag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (28)   
   RefSeq(nuc) (4)   
   GenBank (12)   
   EMBL (12)   
Protein domain (17)   
   Pfam (17)   
All databases (84)   

Download RDF
DBGET integrated database retrieval system