KEGG   Mus musculus (house mouse): 214763
Entry
214763            CDS       T01002                                 
Symbol
Cgas, E330016A19Rik, Mb21d1
Name
(RefSeq) cyclic GMP-AMP synthase
  KO
K17834  cyclic GMP-AMP synthase [EC:2.7.7.86]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04623  Cytosolic DNA-sensing pathway
mmu05163  Human cytomegalovirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    214763 (Cgas)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    214763 (Cgas)
   05171 Coronavirus disease - COVID-19
    214763 (Cgas)
   05168 Herpes simplex virus 1 infection
    214763 (Cgas)
   05163 Human cytomegalovirus infection
    214763 (Cgas)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.86  cyclic GMP-AMP synthase
     214763 (Cgas)
SSDB
Motif
Pfam: Mab-21 Mab-21_C RasGAP_C DUF4699 Spc29 SMODS
Other DBs
NCBI-GeneID: 214763
NCBI-ProteinID: NP_775562
MGI: 2442261
Ensembl: ENSMUSG00000032344
UniProt: Q8C6L5 Q8BSY1
Structure
Position
9:complement(78337800..78350519)
AA seq 507 aa
MEDPRRRTTAPRAKKPSAKRAPTQPSRTRAHAESCGPQRGARSRRAERDGDTTEKPRAPG
PRVHPARATELTKDAQPSAMDAAGATARPAVRVPQQQAILDPELPAVREPQPPADPEARK
VVRGPSHRRGARSTGQPRAPRGSRKEPDKLKKVLDKLRLKRKDISEAAETVNKVVERLLR
RMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFK
RIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRN
PEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQG
ETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCS
YHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQEL
IDRKSKEFLSKKIEYERNNGFPIFDKL
NT seq 1524 nt   +upstreamnt  +downstreamnt
atggaagatccgcgtagaaggacgacggcgccacgcgctaagaagccgtccgcgaagcgc
gccccgacgcagcccagcaggaccagggcccacgcggaaagctgcggcccgcaaaggggg
gctcgatcgcggcgggcggagcgtgacggggacaccacggagaagccacgtgccccaggg
ccccgagtgcatccagcaagggccactgagctcaccaaagatgcacagccctcggccatg
gacgcggcaggagccaccgcgcggcctgccgtccgggtgccccagcagcaggccatcctg
gatccggagctgcccgccgtacgggagccccagccgcccgcggatcccgaggcgcggaaa
gtcgtaaggggacctagccacagaaggggcgcgcgctccaccgggcagcccagagcgccg
cgagggtccaggaaggaaccggacaagctaaagaaggtgctggacaaattgagattgaaa
cgcaaagatatctcggaggcggccgagacggtgaataaagttgtggaacgcctgctgcgc
agaatgcagaaacgggagtcggagttcaaaggtgtggagcagctgaacactggcagctac
tatgaacatgtgaagatttctgctcctaatgaatttgatgttatgtttaaactggaagtc
cccaggattgagctacaagaatattatgaaacaggtgctttctatcttgtgaaattcaaa
agaattccacgaggaaatccgctgagtcatttcttagaaggggaagtattatcagctacc
aagatgctgtcaaagtttaggaaaatcattaaagaagaagttaaagaaatcaaagatata
gatgtcagtgtggagaaggaaaaaccaggaagccctgctgtaacacttcttatcaggaac
cctgaagaaatctctgtggatataattctggctttggagtcaaaaggcagctggcctatt
agtaccaaagaaggactacctattcaaggctggctgggcacaaaagtgaggaccaatcta
agacgagagccgttttatctcgtacccaagaatgcaaaggatggaaatagttttcaagga
gagacctggcgcctctctttctctcacactgaaaagtacattttgaataatcacgggata
gagaaaacatgctgtgaatcttccggagcaaaatgctgcagaaaagaatgtttaaaatta
atgaaataccttttggaacagttgaaaaaagagtttcaagagctggatgcattctgttcc
taccatgtgaaaactgccatctttcacatgtggacccaggacccgcaggacagtcagtgg
gaccccaggaacctcagctcctgcttcgataagttgttagcattctttcttgagtgcctc
aggacagagaaactggatcattattttattccaaagttcaatctattctctcaagaacta
attgaccgaaaaagtaaagaatttctatcgaagaaaattgaatatgaaagaaataatggg
tttccaatttttgacaagctttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (34)   
   PDB (34)   
Protein domain (6)   
   Pfam (6)   
All databases (102)   

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