| Entry |
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| Symbol |
Nlrp3, AGTAVPRL, AII/AVP, Cias1, FCAS, FCU, MWS, Mmig1, NALP3, Pypaf1
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| Name |
(RefSeq) NLR family, pyrin domain containing 3
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| KO |
| K12800 | NACHT, LRR and PYD domains-containing protein 3 |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu04621 | NOD-like receptor signaling pathway |
| mmu04625 | C-type lectin receptor signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
216799 (Nlrp3)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
216799 (Nlrp3)
04623 Cytosolic DNA-sensing pathway
216799 (Nlrp3)
04625 C-type lectin receptor signaling pathway
216799 (Nlrp3)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
216799 (Nlrp3)
05164 Influenza A
216799 (Nlrp3)
09171 Infectious disease: bacterial
05132 Salmonella infection
216799 (Nlrp3)
05135 Yersinia infection
216799 (Nlrp3)
05133 Pertussis
216799 (Nlrp3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
216799 (Nlrp3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:mmu04131]
216799 (Nlrp3)
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:mmu04054]
216799 (Nlrp3)
Membrane trafficking [BR:mmu04131]
Autophagy
Other autophagy associated proteins
TRIM-directed selective autophagy
216799 (Nlrp3)
Pattern recognition receptors [BR:mmu04054]
Cytoplasmic pattern recognition receptors
NOD-like receptors
216799 (Nlrp3)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
11:59432395..59457781
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| AA seq |
1033 aa
MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFN
GEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYL
SRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQERE
HELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWA
LGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGF
DELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDH
PRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQ
QMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILF
EECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGET
VRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQ
QVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMD
HVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNC
CLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLS
HQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSAC
CQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSA
LTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLST
ILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQE
EKPELTIVFEISW |
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| NT seq |
3102 nt +upstreamnt +downstreamnt
atgacgagtgtccgttgcaagctggctcagtatctagaggaccttgaagatgtggacctc
aagaaattcaaaatgcatttggaagattacccgcccgagaaaggctgtatcccagtcccc
aggggccagatggagaaggcagatcacttggatctagccacactcatgattgacttcaat
ggcgaggagaaggcctgggccatggctgtgtggatctttgctgcgatcaacaggcgagac
ctctgggaaaaagctaagaaggaccagccagagtggaatgacacgtgtacatcacattcc
tctatggtatgccaggaggacagccttgaagaagagtggatgggtttgctgggatatctc
tcccgcatctccatttgtaaaaagaagaaagattactgtaagatgtacagacgacatgtg
agaagcaggttctactctatcaaggacaggaacgcgcgtctaggtgagagtgtggacctc
aacagtcgctacacgcagctccaactggtcaaggagcatccaagcaagcaggagcgggag
catgaactcctgaccatcggccggactaaaatgcgggacagccccatgagttcccttaag
ctggagctgctgtttgagcccgaggacgggcactcggagcctgtgcacacagtggtgttc
cagggagcagcaggcatcgggaaaaccatcctagccaggaagattatgttggactgggca
ctgggaaagctcttcaaagacaaatttgactatttgttctttatccactgccgagaggtg
agcctcaggacgccaaggagtctagcagacctgattgtcagctgctggcctgacccaaac
ccaccagtgtgcaagatcctgcgcaagccttccaggatcctcttcctcatggatggcttt
gatgagctacaaggggcctttgacgagcacattggggaggtctgcacagactggcaaaag
gctgtgcggggagacattctgctaagcagcctcatccgaaagaaactgctgcccaaggcc
tctctgctcataacgacgaggccggtagccttggagaaactgcagcatctcctggaccac
ccccgccatgtggagatcctaggtttctctgaggccaaaaggaaggagtatttctttaag
tatttctccaacgagctgcaggcccgggaggccttcaggctgatccaagagaatgaggtc
ctctttaccatgtgcttcatccccctggtctgctggattgtgtgcacggggctaaagcaa
cagatggagaccgggaagagcctggcccagacctccaagaccactacggccgtctacgtc
ttcttcctttccagcctgctgcaatcccgggggggcattgaggagcatctcttctctgac
tacctacaggggctctgttcactggctgcggatggaatttggaaccagaaaatcctattt
gaggagtgtgatctgcggaagcacggcctgcagaagactgacgtctccgctttcctgagg
atgaacgtgttccagaaggaagtggactgcgagagattctacagcttcagccacatgact
ttccaggagttcttcgctgctatgtactatttgctggaagaggaggcagagggggagacc
gtgaggaaaggaccaggaggttgttcagatcttctgaaccgagacgtgaaggtcctacta
gaaaattacggcaagtttgaaaaaggctatctgatttttgttgtccgattcctctttggc
cttgtaaaccaggagagaacctcttatttggagaagaaactaagttgcaagatctctcag
caagtcagactggaactactgaagtggattgaagtgaaagccaaggccaagaagctgcag
tggcagcccagccaactggaactgttctactgcctgtacgagatgcaggaggaagacttt
gtgcagagtgccatggaccactttcccaaaattgagatcaacctctctaccagaatggac
cacgtggtttcctccttttgtattaagaactgtcatagggtcaaaacgctttccctgggt
ttttttcacaactcgcccaaggaggaagaagaagagaggagaggaggtcgacccttggac
caggttcagtgtgttttcccagacactcatgttgcctgttcttccagactggtgaactgc
tgcctcacttctagcttctgccgtggtctcttctcaagtctaagcaccaaccggagcctc
actgaactggacctcagtgacaatactctgggagacccgggcatgagggtgctgtgtgag
gcactccagcacccaggctgtaacattcagagactgtggttggggcgctgcggactgtcc
catcaatgctgcttcgacatctcctctgtcctgagcagcagccagaagctggtggagctg
gacctcagtgacaatgccctgggggactttggaatcagattgctgtgtgtgggactgaag
cacctgctctgcaacctccagaaactgtggttggtgagctgctgtctcacatccgcgtgt
tgtcaggatctcgcattggttctgagctccaaccattctctgaccagactgtacattgga
gaaaatgccttgggagactcaggagtccaagttttgtgtgaaaagatgaaggacccacag
tgtaacttgcagaagctggggttggtgaattccggccttacttcaatctgttgttcagct
ctgacctctgtgctcaaaaccaaccagaacttcacacacctctatctacgaagcaatgcc
cttggagacacaggactcaggctcctctgtgaggggcttctgcacccggactgtaaacta
cagatgctggaattagacaactgcagcctcacctcacacagctgctggaatctctccaca
attctgacccacaaccacagccttcggaagctgaacctgggcaacaatgatcttggcgat
ctgtgcgtggtgaccctctgtgaggtgctgaaacagcagggctgcctcctgcagagccta
cagttgggtgaaatgtacttaaatcgtgaaacaaaacgtgccttagaagcgctccaggaa
gaaaagcctgagctgactatagtcttcgagatttcctggtag |
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