KEGG   Mus musculus (house mouse): 21808
Entry
21808             CDS       T01002                                 
Symbol
Tgfb2, Tgf-beta2, Tgfb-2
Name
(RefSeq) transforming growth factor, beta 2
  KO
K13376  transforming growth factor beta-2
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04010  MAPK signaling pathway
mmu04060  Cytokine-cytokine receptor interaction
mmu04068  FoxO signaling pathway
mmu04110  Cell cycle
mmu04218  Cellular senescence
mmu04350  TGF-beta signaling pathway
mmu04380  Osteoclast differentiation
mmu04390  Hippo signaling pathway
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu05140  Leishmaniasis
mmu05142  Chagas disease
mmu05144  Malaria
mmu05145  Toxoplasmosis
mmu05146  Amoebiasis
mmu05152  Tuberculosis
mmu05161  Hepatitis B
mmu05166  Human T-cell leukemia virus 1 infection
mmu05200  Pathways in cancer
mmu05205  Proteoglycans in cancer
mmu05206  MicroRNAs in cancer
mmu05210  Colorectal cancer
mmu05211  Renal cell carcinoma
mmu05212  Pancreatic cancer
mmu05220  Chronic myeloid leukemia
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
mmu05321  Inflammatory bowel disease
mmu05323  Rheumatoid arthritis
mmu05410  Hypertrophic cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    21808 (Tgfb2)
   04350 TGF-beta signaling pathway
    21808 (Tgfb2)
   04390 Hippo signaling pathway
    21808 (Tgfb2)
   04068 FoxO signaling pathway
    21808 (Tgfb2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    21808 (Tgfb2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    21808 (Tgfb2)
   04218 Cellular senescence
    21808 (Tgfb2)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    21808 (Tgfb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    21808 (Tgfb2)
   05206 MicroRNAs in cancer
    21808 (Tgfb2)
   05205 Proteoglycans in cancer
    21808 (Tgfb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    21808 (Tgfb2)
   05212 Pancreatic cancer
    21808 (Tgfb2)
   05225 Hepatocellular carcinoma
    21808 (Tgfb2)
   05226 Gastric cancer
    21808 (Tgfb2)
   05220 Chronic myeloid leukemia
    21808 (Tgfb2)
   05211 Renal cell carcinoma
    21808 (Tgfb2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    21808 (Tgfb2)
   05161 Hepatitis B
    21808 (Tgfb2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    21808 (Tgfb2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    21808 (Tgfb2)
   05144 Malaria
    21808 (Tgfb2)
   05145 Toxoplasmosis
    21808 (Tgfb2)
   05140 Leishmaniasis
    21808 (Tgfb2)
   05142 Chagas disease
    21808 (Tgfb2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    21808 (Tgfb2)
   05321 Inflammatory bowel disease
    21808 (Tgfb2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    21808 (Tgfb2)
   05414 Dilated cardiomyopathy
    21808 (Tgfb2)
   05415 Diabetic cardiomyopathy
    21808 (Tgfb2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    21808 (Tgfb2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:mmu04052]
    21808 (Tgfb2)
   00536 Glycosaminoglycan binding proteins [BR:mmu00536]
    21808 (Tgfb2)
Cytokines and neuropeptides [BR:mmu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   21808 (Tgfb2)
Glycosaminoglycan binding proteins [BR:mmu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   21808 (Tgfb2)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta Disaggr_repeat
Other DBs
NCBI-GeneID: 21808
NCBI-ProteinID: NP_033393
MGI: 98726
Ensembl: ENSMUSG00000039239
UniProt: P27090 Q8CDZ9 Q3TWH5
Structure
Position
1:complement(186354984..186441504)
AA seq 414 aa
MHYCVLSTFLLLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEP
DEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHLPSENAIPP
TFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSP
TQRYIDSKVVKTRAEGEWLSFDVTDAVQEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIP
NKSEELEARFAGIDGTSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYRLESQQSSRRK
KRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQH
TKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS
NT seq 1245 nt   +upstreamnt  +downstreamnt
atgcactactgtgtgctgagcacctttttgctcctgcatctggtcccggtggcgctcagt
ctgtctacctgcagcaccctcgacatggatcagtttatgcgcaagaggatcgaggccatc
cgcgggcagatcctgagcaagctgaagctcaccagccccccggaagactatccggagccg
gatgaggtccccccggaggtgatttccatctacaacagtaccagggacttactgcaggag
aaggcaagccggagggcagccgcctgcgagcgcgagcggagcgacgaggagtactacgcc
aaggaggtttataaaatcgacatgccgtcccacctcccctccgaaaatgccatcccgccc
actttctacagaccctacttcagaatcgtccgctttgatgtctcaacaatggagaaaaat
gcttcgaatctggtgaaggcagagttcagggtcttccgcttgcaaaaccccaaagccaga
gtggccgagcagcggattgaactgtatcagatccttaaatccaaagacttaacatctccc
acccagcgctacatcgatagcaaggttgtgaaaaccagagcggagggtgaatggctctcc
ttcgacgtgacagacgctgtgcaggagtggcttcaccacaaagacaggaacctggggttt
aaaataagtttacactgcccctgctgtaccttcgtgccgtctaataattacatcatcccg
aataaaagcgaagagctcgaggcgagatttgcaggtattgatggcacctctacatatgcc
agtggtgatcagaaaactataaagtccactaggaaaaaaaccagtgggaagaccccacat
ctcctgctaatgttgttgccctcctacagactggagtcacaacagtccagccggcggaag
aagcgcgctttggatgctgcctactgctttagaaatgtgcaggataattgctgccttcgc
cctctttacattgattttaagagggatcttggatggaaatggatccatgaacccaaaggg
tacaatgctaacttctgtgctggggcatgcccatatctatggagttcagacactcaacac
accaaagtcctcagcctgtacaacaccataaatcccgaagcttccgcttccccttgctgt
gtgtcccaggatctggaaccactgaccattctctattacattggaaatacgcccaagatc
gaacagctttccaatatgattgtcaagtcttgtaaatgcagctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (31)   
   KEGG PATHWAY (31)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (24)   
   RefSeq(nuc) (4)   
   GenBank (10)   
   EMBL (10)   
3D Structure (2)   
   PDB (2)   
Protein domain (3)   
   Pfam (3)   
All databases (85)   

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