KEGG   Mus musculus (house mouse): 21846
Entry
21846             CDS       T01002                                 
Symbol
Tie1, D430008P04Rik, TIE, tie-1
Name
(RefSeq) tyrosine kinase with immunoglobulin-like and EGF-like domains 1
  KO
K05120  tyrosine kinase receptor 1 [EC:2.7.10.1]
Organism
mmu  Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    21846 (Tie1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     21846 (Tie1)
Protein kinases [BR:mmu01001]
 Receptor tyrosine kinases (RTK)
  TIE family
   21846 (Tie1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase fn3 ig Pur_ac_phosph_N I-set Ig_3 Ig_2 EGF_2 hEGF C2-set Laminin_EGF Pkinase_fungal Haspin_kinase TadZ_N DUF4702
Other DBs
NCBI-GeneID: 21846
NCBI-ProteinID: NP_035717
MGI: 99906
Ensembl: ENSMUSG00000033191
UniProt: Q06806
Position
4:complement(118328388..118347046)
AA seq 1134 aa
MVWWGSSLLLPTLFLASHVGASVDLTLLANLRITDPQRFFLTCVSGEAGAGRSSDPPLLL
EKDDRIVRTFPPGQPLYLARNGSHQVTLRGFSKPSDLVGVFSCVGGAGARRTRVLYVHNS
PGAHLFPDKVTHTVNKGDTAVLSAHVHKEKQTDVIWKNNGSYFNTLDWQEADDGRFQLQL
QNVQPPSSGIYSATYLEASPLGSAFFRLIVRGCGAGRWGPGCVKDCPGCLHGGVCHDHDG
ECVCPPGFTGTRCEQACREGRFGQSCQEQCPGTAGCRGLTFCLPDPYGCSCGSGWRGSQC
QEACAPGHFGADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDRIPQILSMATEVEF
NIGTMPRINCAAAGNPFPVRGSMKLRKPDGTMLLSTKVIVEPDRTTAEFEVPSLTLGDSG
FWECRVSTSGGQDSRRFKVNVKVPPVPLTAPRLLAKQSRQLVVSPLVSFSGDGPISSVRL
HYRPQDSTIAWSAIVVDPSENVTLMNLKPKTGYNVRVQLSRPGEGGEGGWGPSALMTTDC
PEPLLQPWLESWHVEGPDRLRVSWSLPSVPLSGDGFLLRLWDGARGQERRENISFPQART
ALLTGLTPGTHYQLDVRLYHCTLLGPASPPAHVHLPPSGPPAPRHLHAQALSDSEIQLMW
QHPEAPSGPISKYIVEIQVAGGSGDPQWMDVDRPEETSIIVRGLNASTRYLFRVRASVQG
LGDWSNTVEEATLGNGLQSEGPVRESRAAEEGLDQQLVLAVVGSVSATCLTILAALLALV
CIRRSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKPQPEPLSYPVLEWEDITFEDL
IGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLL
GACENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAA
NGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYVKKTMGRLPVRWMAIES
LNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYE
LMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTYAGIDATAEEA
NT seq 3405 nt   +upstreamnt  +downstreamnt
atggtctggtggggatcctctttgctgctccccactcttttcttggcctctcatgttggt
gcgtctgttgacttaacattgctggccaacctgcgcatcacagacccccagcgtttcttc
ctgacctgcgtgtctggtgaggccggagcagggaggagctcggacccgcccctgctgctg
gagaaggatgatcgcatcgtgcgcaccttcccgcctgggcagcccctgtacctggcacgc
aacggttctcaccaggtcacgctgaggggcttctccaagccctcggatttggtaggcgtc
ttctcctgtgtgggtggtgctggcgcgcggcgcactcgagttctctatgtgcacaacagc
ccaggggcacacctgtttccagacaaggtcacacacacggtgaacaaaggtgacactgct
gtgctttctgcccatgtgcacaaggaaaagcagactgacgtgatctggaagaacaacgga
tcctacttcaataccctagactggcaagaggccgatgacgggcgttttcaactgcagctc
caaaatgtacagccaccatcaagtggcatctacagtgccacctacctagaggccagcccc
ctgggcagtgccttctttcggctcatcgtgcgaggctgtggggctggacgctgggggcca
ggatgtgtcaaggattgcccaggctgcctgcatggaggtgtctgtcatgaccatgatggc
gaatgtgtgtgtcccccaggattcactggcacccgctgtgagcaggcctgcagggagggt
cgttttggacagagctgtcaggaacagtgcccaggcacagcaggttgtagaggtctcacc
ttctgcctcccggatccctatggctgttcctgtggatctggctggagaggaagccagtgc
caggaagcatgtgcacctggtcattttggggctgattgtcgcctccagtgccagtgtcaa
aatggtggcacttgtgaccggttcagcggctgcgtctgcccctctgggtggcatggagtc
cactgtgaaaagtcagaccggatcccccagatcctcagtatggccacagaggtggagttc
aacatagggacgatgccccggatcaactgtgcagctgccgggaatcccttcccagtgcgg
ggcagcatgaaacttcgcaagccagatggcaccatgcttttgtctaccaaagtcattgtg
gagccagacaggaccacagcagagtttgaagtgcccagtttgactcttggggacagtggg
ttctgggaatgccgcgtatcgacttctggtggccaagacagccggcgcttcaaggtcaat
gtcaaagtacccccagtgcctttgactgcacctcgactcctggccaagcagagccgtcag
cttgtggtctccccactggtctcctttagtggggatggacccatctcctctgtccgcctg
cactaccggccccaggacagcacgattgcctggtctgccattgtggtggatcccagtgag
aatgtgacattaatgaacctgaagccaaagacaggatacaatgtccgagtgcagctgagc
cggccaggggaaggaggagaaggaggctggggaccttctgcccttatgactactgactgt
cctgagcctttgctgcagccctggctagagagctggcacgtggagggtcctgacaggctc
cgtgtgagctggtctctaccctcggtgccactgtccggtgatggtttcctgctgcgcctg
tgggatggggcccggggacaggagaggcgggagaacatctcattcccccaggcccgcact
gccctcctgactggactcacgccgggcacccactaccagctggatgtgcgactgtatcac
tgtaccctcctgggccctgcctcaccccctgcgcatgtgcacctgccccccagcgggcct
ccagctccccgccacctccatgcccaggccctctcagactctgagattcaactcatgtgg
cagcatcccgaggctccgtctgggcctatatccaagtacatcgtggagattcaggtggcc
gggggctcaggagacccacagtggatggatgtagacaggcccgaggagacaagcatcatt
gttcgtggcctcaatgctagcacacgatatcttttccgtgtgcgggccagtgtgcagggt
cttggcgactggagcaatacagtagaagaggccactctgggcaatgggctgcagagtgag
ggcccagtccgagaaagccgggcagctgaagaaggcctggatcagcagctggtcctggct
gtggtaggttccgtctctgccacctgcctcaccatcctggctgcccttttagccttggtg
tgtatccgaagaagctgcctacatcggagacgcaccttcacttaccagtcaggatcgggt
gaagagaccatcctgcagttcagctcagggaccttgaccttgacccggcgaccgaagcca
cagcctgagcccttgagttaccccgtgctggagtgggaggacatcacctttgaggacctc
ataggggagggcaactttggccaagtgatccgggccatgatcaagaaggacgggctcaag
atgaacgcagccatcaagatgctaaaagagtatgcgtctgaaaatgaccatcgagacttt
gcaggtgaactagaagttctgtgcaaactaggacaccaccccaatattatcaacctcttg
ggggcctgtgagaaccgaggctacttgtatattgctatcgaatacgccccctatggaaac
ctactggacttcctgagaaagagcagggtcctggagactgatccagcttttgctcgagag
catgggacggcctccacactcagctctcggcagctgctgcgctttgccagtgatgcagcc
aacggcatgcagtaccttagtgagaagcagttcattcacagggacctggctgcccgaaat
gtgctggtcggagagaacctggcctccaagattgcagactttggcctttctcgaggggag
gaggtgtatgtgaagaagacaatgggccgtctccctgtgcgttggatggccattgagtcc
ctcaactacagcgtctataccaccaagagtgatgtctggtcctttggggtcctcctctgg
gagatagtgagccttggaggcacgccctactgtggcatgacctgtgctgagctctacgag
aagctgcctcaaggctatcgcatggagcagcctcgaaactgcgatgacgaagtgtacgag
ctgatgcggcagtgctggcgggatcggccctatgagcgccccccctttgctcagatcgca
ctacagttgggccgcatgctggaagccaggaaggcctacgtgaacatgtcgctgtttgag
aacttcacctatgcgggcatcgatgccacagctgaggaggcctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (25)   
   RefSeq(nuc) (1)   
   GenBank (12)   
   EMBL (12)   
Protein domain (16)   
   Pfam (16)   
All databases (78)   

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