KEGG   Mus musculus (house mouse): 21969
Entry
21969             CDS       T01002                                 
Symbol
Top1, D130064I21Rik, Top-1
Name
(RefSeq) topoisomerase (DNA) I
  KO
K03163  DNA topoisomerase I [EC:5.6.2.1]
Organism
mmu  Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mmu03032]
    21969 (Top1)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     21969 (Top1)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Topoisomerases
   21969 (Top1)
SSDB
Motif
Pfam: Topoisom_I Topoisom_I_N Topo_C_assoc
Other DBs
NCBI-GeneID: 21969
NCBI-ProteinID: NP_033434
MGI: 98788
Ensembl: ENSMUSG00000070544
UniProt: Q04750 Q3ULF5 Q3TPX7
Position
2:160487901..160564684
AA seq 767 aa
MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKDKDKDREKSKHSNSEHKDSE
KKHKEKEKTKHKDGSSEKHKDKHKDRDKERRKEEKIRAAGDAKIKKEKENGFSSPPRIKD
EPEDDGYFAPPKEDIKPLKRLRDEDDADYKPKKIKTEDIKKEKKRKSEEEEDGKLKKPKN
KDKDKKVAEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPESV
KFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLS
KCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPP
GLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTE
NIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVA
LYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYY
NKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITL
QQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQL
ADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGT
SKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF
NT seq 2304 nt   +upstreamnt  +downstreamnt
atgagcggggaccatctccacaacgattcccagatcgaagcggatttccgattgaatgat
tctcacaaacacaaagataaacacaaagatcgagaacaccggcataaggagcacaagaag
gataaggataaggaccgggaaaagtctaagcatagcaacagtgaacataaagattctgaa
aagaaacacaaagagaaagagaaaaccaaacacaaagatggcagctcagaaaaacataaa
gacaaacataaagacagagacaaggaaagacgaaaggaggaaaagattagagctgctggg
gatgcaaaaataaagaaggaaaaggaaaatggcttctctagtccgccacgaattaaagat
gaacctgaggatgatggctattttgctcctccaaaagaggatattaagccattgaagagg
cttcgagatgaagatgatgctgattataaacctaagaaaattaagacagaagatatcaag
aaggagaagaaaagaaaatcagaagaggaagaggatggtaaacttaaaaagcccaagaat
aaagataaagataaaaaagttgctgagccagataataagaaaaagaagccgaaaaaggaa
gaggaacagaagtggaaatggtgggaagaagaacgttatccagaaggcatcaaatggaaa
ttcctagagcataaagggcctgtcttcgctccaccatatgagcctctgccagagagtgtc
aagttttactatgatggtaaagttatgaagctgagtcctaaagcagaagaagtagctaca
ttctttgcaaaaatgcttgaccacgaatatactactaaggaaatattcaggaaaaatttc
tttaaagattggagaaaggaaatgactaatgacgaaaaaaatacgattaccaacctaagc
aaatgcgactttacacagatgagccagtatttcaaagcgcagtcagaagctcggaaacag
atgagcaaggaagaaaaattgaaaatcaaagaagaaaatgaaaagttattgaaagaatac
ggcttttgtgtaatggataatcatagagagcggattgccaacttcaagatagagcctccg
gggcttttccgaggccgagggaaccaccccaagatgggtatgctgaagagaaggatcatg
cctgaggacatcatcatcaactgtagcaaagacgcaaaggttccttctccccctcctgga
cataaatggaaggaagtccgacatgataacaaggttacttggctggtctcctggacagag
aatatccaaggttctatcaaatatatcatgctgaatcccagttcacgaatcaagggtgag
aaagactggcagaagtatgagactgcgcggcgtctgaagaagtgtgtggacaagatccga
aatcagtatcgggaagactggaagtccaaagagatgaaagttcgtcagagagctgtagca
ctgtacttcattgataagcttgctctgagagcaggcaatgagaaggaagaaggagagacg
gcagacactgtgggctgctgttcacttagagtggaacacatcaatttacacccagaattg
gatggtcaggagtatgtggtggaatttgactttcctgggaaggactcaatcagatactat
aacaaagtcccagttgagaaacgagtttttaaaaacttacaactgtttatggagaacaag
cagcctgaggacgatctttttgatcgacttaatactggtattctaaataaacatcttcag
gatctcatggagggcttgactgccaaggtgttccgtacctacaatgcctccatcacacta
cagcagcagcttaaagagctcacagcccctgatgagaatgtaccagcgaagattctatct
tataaccgtgccaatcgagctgttgcaattctttgtaaccaccagagggcgccaccaaag
acctttgagaagtcaatgatgaacttgcagtctaagattgatgccaagaaagatcagtta
gcagatgctcgaagggacctgaaaagtgctaaggctgatgccaaagtcatgaaggatgca
aagaccaagaaggtagtagagtcaaaaaagaaggctgtacagagactagaagagcagttg
atgaagctggaagttcaagccacagatcgagaggagaacaaacaaattgccttggggacc
tccaaactcaattatctggaccctaggatcacagtggcttggtgcaaaaagtggggggtc
ccaattgagaagatttacaacaaaacccagagggagaagtttgcttgggccattgatatg
actgatgaggactacgagttttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (8)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (40)   
   RefSeq(nuc) (4)   
   GenBank (18)   
   EMBL (18)   
Protein domain (3)   
   Pfam (3)   
All databases (84)   

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