KEGG   Mus musculus (house mouse): 21975
Entry
21975             CDS       T01002                                 
Symbol
Top3a
Name
(RefSeq) topoisomerase (DNA) III alpha
  KO
K03165  DNA topoisomerase III [EC:5.6.2.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03440  Homologous recombination
mmu03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    21975 (Top3a)
   03460 Fanconi anemia pathway
    21975 (Top3a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mmu03032]
    21975 (Top3a)
   03400 DNA repair and recombination proteins [BR:mmu03400]
    21975 (Top3a)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     21975 (Top3a)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Topoisomerases
   21975 (Top3a)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    Bloom's syndrome complex (BTR)
     21975 (Top3a)
   FA (Fanconi anemia) pathway
     21975 (Top3a)
SSDB
Motif
Pfam: Topoisom_bac zf-GRF Toprim zf-C4_Topoisom zf-C2H2_10
Other DBs
NCBI-GeneID: 21975
NCBI-ProteinID: NP_033436
MGI: 1197527
Ensembl: ENSMUSG00000002814
UniProt: O70157 Q5NCT2
Position
11:complement(60629014..60668099)
AA seq 1003 aa
MIFPVTLLAFQWHRRPGGRALSRAAMEVAFRGVRKVLCVAEKNDAAKGIADLLSNGRMRR
KEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
YCPENFIDIKKTLERETHHCQALVIWTDCDREGENIGFEIIHVCKAVKPNLRVLRARFSE
ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPEVFHKIKVTHDHKDGTVEFNWKRYRLFNHTACLVLY
QLCMEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPKDLNLVALVEQQTVDPHWGAFAQTILERGGPTPRNGSKSDQAHPPIHPT
KYTSGLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDV
YPYDHWSDKLLPVYEQGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTSDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKK
DKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGERTEMAQQEEIYPAMPEPVRKCPQ
CNKDMVLKTKKSGGFYLSCMGFPECRSAVWFPDSVLEASRDNSVCSVCQPPPVYRLKLKF
KRGSLPPAMPLEFVGCIGGCDETLKEIFGLRFPRALPRASQPSGHLQASQALNRMDSSQH
NLSQPLVNRHTRPSKTVAQALLPPTTAGESNSVTCNCGREAVLLTVRKQGPNQGRHFYKC
SNGDCNFFLWADSSHSTGGGTPTSASGPPGSSVGCPSSVGSHMDGFGSLGSDSDGGTPCL
CGQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENVAPGSFAAPAWPGGRGKAQ
RPEAASKRPRAGSSDAGSTVKKPRKCSLCHQPGHTRTFCPQNR
NT seq 3012 nt   +upstreamnt  +downstreamnt
atgatcttcccggtcaccctcttagcgtttcagtggcaccgacggcctggaggccgtgcc
ctgtcccgcgctgccatggaagtggccttccgaggagtgcgaaaagttctctgcgtggcg
gagaaaaacgacgctgccaaggggatcgccgacttgctgtccaacgggcgtatgaggcgg
aaagaaggcctttctaaattcaacaagatttatgaatttgactatcatctgtatggccag
aatgttactatgataatgacttcagtctctggacatttgctggctcatgacttccagatg
cagtttcggaaatggcagagctgcaatccccttgtcctctttgaagcagaaattgaaaag
tattgcccagaaaattttatagacatcaagaaaactctagaacgagagacacatcattgt
caggccctggtgatctggacggactgtgatagggaaggtgagaacatcggctttgagatt
atccacgtatgcaaggctgtaaaacccaatctacgggtgctgagagcccgcttctctgag
atcacgccacacgccgtcagaacagcctgtgaaaacctaactgagcctgaccagagagtg
agtgacgcagtggatgtgaggcaagagctggacctgaggatcggagctgccttcacaagg
ttccagaccctgcggctccagaggatcttccctgaggtgctggcagagcagctcatcagc
tacggcagttgccagttcccaacactggggtttgtggtggagaggttcaaggccattcag
gcttttgtgccagaagtcttccacaaaattaaagtaactcatgaccacaaagatgggacc
gtagagttcaactggaaacgataccgtctctttaaccacacagcttgtcttgtcctttat
cagttgtgcatggaggatcccatggcgactgtggtagaggtcagatctaagccaaagagc
aagtggaggccgcaggctttggacacggtggagctagagaaactggcatctcggaaattg
agaataaatgccaaagaaaccatgaggatcgcggaaaagctctatacacaagggtacatc
agctacccccggacagaaacaaacatcttccccaaagacttaaacctggttgcattggta
gaacagcagaccgtggatccacactggggggcttttgctcagaccattctagagcgaggt
ggccctactccccgaaacgggagcaagtctgatcaagctcaccctcccattcaccccacc
aaatacaccagcggcttgcagggagatgatcggcgactgtacgagttcattgttcgccat
ttcctggcttgctgctctcaggacgctcaggggcaagagactaccgtagagatcgacatt
gcccaagagcgctttgtggcccacgggctcatcattctggcccgtaactacctagatgtg
tatccgtatgatcactggagtgacaagctcctccccgtctatgaacaaggctcccacttc
cagcccagcactgtggaaatggtggatggagagactagcccaccccaactgcttaccgaa
gctgacctcatcgccctcatggagaaacatgggatcggtactgatgcaactcatgcagaa
cacattgagaccatcaaagcccggatgtatgtgggactcacctcagacaagcggttcctg
ccggggcacctgggcatgggacttgtagaaggttacgattccatgggttatgagatgtcc
aagcctgacctccgtgccgagctggaagctgatctcaagctgatctgtgagggcaagaag
gataagtttcaagttctaaggcagcaagtgcaaaaatacaagcaggttttcattgaagca
gtggcgaaggcaaagaagttggatgaggctttatctcagtacttaggagaaagaacagag
atggcccagcaagaagagatctacccagccatgccagagcctgttcggaagtgcccacag
tgtaacaaggatatggtcctcaagaccaagaagagtggtgggttctacctcagctgcatg
gggttcccagagtgtcggtcagctgtgtggtttcctgactcggtgctggaggccagcagg
gacaacagtgtgtgttctgtttgtcagccaccccctgtgtacaggttgaagttgaagttt
aagcgtggtagccttcccccagctatgcccctggagtttgtcggctgcataggtggatgt
gatgagactttgaaggaaatcttcggcctgcgatttccacgggctctcccaagagctagc
cagccctctggccacctgcaggccagccaggccctcaacaggatggacagcagtcagcat
aacctgtctcaacctctggttaacagacatactagaccttcaaagacagtggcccaagcc
ttgctaccacccactactgctggtgaaagcaactctgtgacttgcaattgtggccgggag
gctgtgctgctcactgtccgcaagcagggccccaaccagggccggcatttctacaagtgc
agtaatggtgactgcaacttcttcctgtgggctgacagcagccattccactggaggaggg
acccccacctctgcatcaggacccccaggcagctctgtaggatgcccatccagtgtaggc
agccacatggatgggtttggcagccttggcagcgacagtgatggaggtacaccctgcctg
tgcgggcagcctgctgtcacacggactgttcagaaggatggacccaacaaaggacgccag
ttccacacctgtgccaagccacgagagcagcagtgtggcttctttcagtgggtggatgag
aatgtggccccaggaagttttgcagcccctgcatggccaggaggcagaggaaaagcccag
agaccagaggctgcaagcaaaagaccaagagctggttcctcagatgcagggtccacagta
aaaaagcctcggaaatgtagcctttgtcaccagcctggacacacccgaaccttttgtcct
cagaacagatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
Protein domain (5)   
   Pfam (5)   
All databases (74)   

Download RDF
DBGET integrated database retrieval system