KEGG   Mus musculus (house mouse): 22040
Entry
22040             CDS       T01002                                 
Symbol
Trex1
Name
(RefSeq) three prime repair exonuclease 1
  KO
K10790  three prime repair exonuclease 1 [EC:3.1.11.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04623  Cytosolic DNA-sensing pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    22040 (Trex1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mmu03400]
    22040 (Trex1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.11.2  exodeoxyribonuclease III
     22040 (Trex1)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  Other factors with a suspected DNA repair function
   Nucleases
    22040 (Trex1)
SSDB
Motif
Pfam: RNase_H_2 RNase_T
Other DBs
NCBI-GeneID: 22040
NCBI-ProteinID: NP_001012236
MGI: 1328317
Ensembl: ENSMUSG00000049734
UniProt: Q91XB0
Structure
Position
9:complement(108887000..108888791)
AA seq 314 aa
MGSQTLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRP
PRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCC
LVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSPSGNGSRKSYSLG
SIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGTPATTG
TTNLRPHAATATTPLATANGSPSNGRSRRPKSPPPEKVPEAPSQEGLLAPLSLLTLLTLA
IATLYGLFLASPGQ
NT seq 945 nt   +upstreamnt  +downstreamnt
atgggctcacagaccctgccccatggtcacatgcagaccctcatcttcttagacctggaa
gccactggcctgccttcgtctcggcccgaagtcacagagctgtgcctgctggctgtccac
agacgtgctctggagaacacttccatttctcagggacatccacctccagtgcccagaccg
ccccgtgtggtggacaagctctctctgtgcattgctccagggaaagcctgtagccctggg
gccagtgagatcacaggtctgagcaaagctgagctggaagtacaggggcgtcaacgcttc
gatgacaacctggccatcctgctccgagccttcctgcagcgccagccacagccttgctgc
cttgtggcacacaacggtgaccgctatgactttcctctgctccagacagagcttgctagg
ctgagcactcccagtcccctagatggtaccttctgtgtggacagcatcgctgccctaaag
gccttggaacaagctagcagcccctcagggaatggttcgaggaaaagctacagcctgggc
agcatctacacccgcctgtactggcaagcaccgacagactcacatactgctgaaggtgat
gttctaaccctgctcagcatctgtcagtggaagccacaggccctactgcagtgggtggac
gaacatgcccggccctttagcaccgtcaagcccatgtacggcactccggctaccactgga
acaaccaacctaaggccacatgctgccacagctactacacccctggccacagccaatgga
agtcccagcaatggcaggagcaggcgacctaagagtcctcctccagagaaggtcccagaa
gccccatcacaggaggggctgctggccccactgagcctgctgaccctcctgaccttggca
atagccactctgtatggactcttcctggcctcacctgggcagtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
3D Structure (24)   
   PDB (24)   
Protein domain (2)   
   Pfam (2)   
All databases (77)   

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