KEGG   Mus musculus (house mouse): 22236
Entry
22236             CDS       T01002                                 
Symbol
Ugt1a2, UDPGT_1-2, Ugt1
Name
(RefSeq) UDP glucuronosyltransferase 1 family, polypeptide A2
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00040  Pentose and glucuronate interconversions
mmu00053  Ascorbate and aldarate metabolism
mmu00140  Steroid hormone biosynthesis
mmu00830  Retinol metabolism
mmu00860  Porphyrin metabolism
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu00982  Drug metabolism - cytochrome P450
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01240  Biosynthesis of cofactors
mmu04976  Bile secretion
mmu05204  Chemical carcinogenesis - DNA adducts
mmu05207  Chemical carcinogenesis - receptor activation
Module
mmu_M00014  Glucuronate pathway (uronate pathway)
mmu_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    22236 (Ugt1a2)
   00053 Ascorbate and aldarate metabolism
    22236 (Ugt1a2)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    22236 (Ugt1a2)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    22236 (Ugt1a2)
   00860 Porphyrin metabolism
    22236 (Ugt1a2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    22236 (Ugt1a2)
   00982 Drug metabolism - cytochrome P450
    22236 (Ugt1a2)
   00983 Drug metabolism - other enzymes
    22236 (Ugt1a2)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    22236 (Ugt1a2)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    22236 (Ugt1a2)
   05207 Chemical carcinogenesis - receptor activation
    22236 (Ugt1a2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:mmu01003]
    22236 (Ugt1a2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     22236 (Ugt1a2)
Glycosyltransferases [BR:mmu01003]
 Others
  Hydrophobic molecule
   22236 (Ugt1a2)
SSDB
Motif
Pfam: UDPGT EryCIII-like_C Glyco_tran_28_C Pox_A14
Other DBs
NCBI-GeneID: 22236
NCBI-ProteinID: NP_038729
MGI: 3576049
Ensembl: ENSMUSG00000090171
UniProt: P70691
Position
1:88128333..88147724
AA seq 533 aa
MDTGLCVPLRGISGLLLLLCALPWAEGAKVLVLPMEGSQWLSMRDVVRELHARGHQTVVL
ASEVTVHIKGEDFFTLKTYAFPYTKEEYQQEILSDIEKTFKTQHFVKAFFETTASIRNFF
DLYSNSCIALLHNKMLIQQLNSSFFDVILTDPIFPCGAVLAKYLQIPAVFILRSLSCGIE
YEATQCPNPSSYIPNLLTRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYESLASELLQR
EVSLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTKKPLSQEFEAYVNASGEH
GIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDL
LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTA
DDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHD
LTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH
NT seq 1602 nt   +upstreamnt  +downstreamnt
atggacacgggactatgtgtgccccttcgaggaatctcagggctgctgctcctgctgtgt
gccctgccctgggctgaaggtgcaaaagtgctggtgttacccatggagggcagccagtgg
ctgagcatgagggatgttgtgcgggagctccacgcccgaggtcaccagactgtggtcctg
gcttcagaggtgactgtgcacatcaaaggagaagacttcttcaccctcaaaacctatgcc
tttccatataccaaggaagaatatcagcaagaaatactgagcgacattgagaagaccttt
aaaacacaacattttgtgaaggccttttttgaaactacagcatctataagaaactttttt
gacctctactcaaattcttgtatagctttattgcacaataagatgctgatccagcaactg
aattccagtttttttgatgtgatcttaacagaccccattttcccctgtggagcagtactg
gccaagtacctacagattcctgctgtgtttattctgcgttctctttcctgtggcatagaa
tatgaggccacacaatgtccaaatccttcctcttatattccgaacctactcacaaggctt
tctgaccacatggacttcctgcaaagggtccagaacatgctgtactatctggtcctgaag
tacatttgccgtttatcaatcactccctatgaaagcctggcctctgagcttttgcagaga
gaagtatccttagtggaggttctcagccatgcatccgtgtggctgttccgaggggacttt
gtactcgactaccccaggcccatcatgcctaacatggtcttcattgggggcataaactgt
gttaccaagaagcccctctctcaggaatttgaagcctatgtcaacgcctctggggagcat
ggcatcgttgttttctctttgggatccatggtctcagagattccggagaagaaagccatg
gaaattgctgaggctttgggcagaattcctcagacggtcctgtggcgctacaccggaact
agaccatcgaatcttgcaaagaacacaattcttgtcaaatggctaccccaaaatgatctg
cttggtcatccaaagactcgggcattcatcacacactctggctcccatggtatttatgaa
ggaatatgcaatggagttccgatggtgatgatgcccctatttggcgatcagatggacaat
gccaagcgcatggaaactcggggagctggggtgaccctgaatgtccttgaaatgactgct
gatgatttggaaaatgcccttaaaactgtcatcaacaacaagagctacaaggagaacatc
atgcgcctctccagccttcacaaggaccgtcctatagagcctctggacctggctgtgttc
tgggtggaatacgtgatgaggcacaagggggcaccacacctgcgcccggccgcccatgac
ctcacctggtatcagtaccactccttggatgtgattggcttcctcctggccattgtgttg
acagtggtcttcattgtctttaaatgttgtgcctatggctgccggaaatgctttggggga
aaggggcgagtgaagaaatcacacaaatccaagacccattga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (13)   
   KEGG MODULE (2)   
Chemical substance (40)   
   KEGG COMPOUND (40)   
Chemical reaction (21)   
   KEGG ENZYME (1)   
   KEGG REACTION (20)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (111)   

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