KEGG   Mus musculus (house mouse): 22259
Entry
22259             CDS       T01002                                 
Symbol
Nr1h3, LXR, RLD1, Unr1
Name
(RefSeq) nuclear receptor subfamily 1, group H, member 3
  KO
K08536  liver X receptor alpha
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03320  PPAR signaling pathway
mmu04148  Efferocytosis
mmu04931  Insulin resistance
mmu04932  Non-alcoholic fatty liver disease
mmu05160  Hepatitis C
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    22259 (Nr1h3)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    22259 (Nr1h3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    22259 (Nr1h3)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    22259 (Nr1h3)
   04931 Insulin resistance
    22259 (Nr1h3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    22259 (Nr1h3)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:mmu03310]
    22259 (Nr1h3)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   Cys4 thyroid hormone receptor-like
    22259 (Nr1h3)
Nuclear receptors [BR:mmu03310]
 1. Thyroid hormone like
  1H. Liver X receptor like receptor
   22259 (Nr1h3)
SSDB
Motif
Pfam: Hormone_recep zf-C4
Other DBs
NCBI-GeneID: 22259
NCBI-ProteinID: NP_001171201
MGI: 1352462
Ensembl: ENSMUSG00000002108
UniProt: Q9Z0Y9 Q91X41
Structure
Position
2:complement(91014406..91033189)
AA seq 445 aa
MSLWLEASMPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGVALGIGLESAE
PTALLPRAETLPEPTELRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFF
RRSVIKGARYVCHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ
EEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAP
DPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLET
SRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAI
SIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDPLMFPRMLMKLVSLRTLSSVHS
EQVFALRLQDKKLPPLLSEIWDVHE
NT seq 1338 nt   +upstreamnt  +downstreamnt
atgtccttgtggctggaggcctcaatgcctgatgtttctcctgattctgcaacggagttg
tggaagacagaacctcaagatgcaggagaccagggaggcaacacttgcatcctcagggag
gaagccaggatgccccagtcaactggggttgctttagggatagggttggagtcagcagag
cctacagccctgctccccagggcagagaccctcccagagccgacagagcttcgtccacaa
aagcggaaaaagggcccagcccccaaaatgctggggaacgagctgtgcagtgtctgtggg
gacaaagcctctggcttccattacaacgtgctgagctgcgagggctgcaagggattcttc
cgccgcagtgtcatcaagggagcacgctatgtctgccacagcggtggccactgccccatg
gacacctacatgcggcggaaatgccaggagtgtcgacttcgcaaatgccgccaggcaggc
atgagggaggagtgtgtgctgtcagaagaacagatccgcttgaagaaactgaagcggcaa
gaagaggaacaggctcaagccacttcggtgtccccaagggtgtcctcacctcctcaagtc
ctgccacagctcagcccagagcagctgggcatgatcgagaagctggtggctgcccagcaa
cagtgtaacaggcgctccttctcagaccgcctgcgcgtcacgccttggcccattgcaccc
gaccctcagagccgggaagcccgacaacagcgctttgcccactttactgagctggccatc
gtgtccgtgcaggagattgttgactttgccaaacagctccctggcttcctacagctcagc
agggaggaccagatcgccttgctgaagacctctgcaatcgaggtcatgcttctggagacg
tcacggaggtacaaccccggcagtgagagcatcaccttcctcaaggacttcagttacaac
cgggaagactttgccaaagcagggctgcaggtggagttcatcaaccccatctttgagttc
tccagagccatgaatgagctgcaactcaatgatgctgagtttgctctgctcattgccatc
agcatcttctctgcagaccggcccaacgtgcaggaccagctccaagtagagaggctgcaa
cacacatatgtggaggccctgcacgcctacgtctccatcaaccacccccacgacccactg
atgttcccacggatgctaatgaagctggtgagcctccgtactttgagcagcgtccattca
gagcaagtgtttgcccttcgcctgcaggacaaaaagcttccccctctgctgtctgagatc
tgggatgtccacgagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (20)   
   RefSeq(nuc) (6)   
   GenBank (7)   
   EMBL (7)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (53)   

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