KEGG   Mus musculus (house mouse): 223435
Entry
223435            CDS       T01002                                 
Symbol
Trio, 6720464I07Rik, Solo
Name
(RefSeq) triple functional domain (PTPRF interacting)
  KO
K08810  triple functional domain protein [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    223435 (Trio)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    223435 (Trio)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     223435 (Trio)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: CAMK group
  Trio family [OT]
   223435 (Trio)
Membrane trafficking [BR:mmu04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    223435 (Trio)
SSDB
Motif
Pfam: SH3-RhoG_link RhoGEF Pkinase Spectrin PK_Tyr_Ser-Thr I-set PH Ig_3 SH3_1 ig CRAL_TRIO_2 PH_10 SH3_2 CRAL_TRIO IQ_SEC7_PH SH3_9 Ig_2 PH_19 PH_13 V-set
Other DBs
NCBI-GeneID: 223435
NCBI-ProteinID: NP_001074771
MGI: 1927230
Ensembl: ENSMUSG00000022263
UniProt: Q0KL02
Position
15:complement(27730735..28025954)
AA seq 3103 aa
MSGSSGGATAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHIALIIKPDNFWQKQRTNFGSSKFEFE
TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEEYISNAAHMLSRLEELQDV
LAKKELPQDLEGARNMIDEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSDSFPKKNSGSG
NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIK
QIANQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
ADVFLKYLHRNSVSMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTVHLRGALKEPIHIPKTAPAARQKGRR
DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHAKKLAHKH
KKSREVRKSADAGSQKDSDDSAATPQDETIEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKCSSLKRRHYVLQELVET
ERDYVRDLGCVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
PEKLGSLFVKHERRLHMYIVYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
VQRIMKYQLLLKDFLKYSKKASLDTSELEKAVEVMCIVPKRCNDMMNVGRLQGFDGKIVA
QGKLLLQDTFLVTDQDAGLLPRCKERRVFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
SCLCLEENVESDPCKFALTSRTGDAVETFVLHSSSPSVRQTWIHEINQILENQRNFLNAL
TSPIEYQRNHSGGGGSGSGGSSGGGGGSGGSGASSGGSSSHGSGPSSCSSGPSSSRSRPS
RIPQPVRHHPPMLVSSAASSQAEADKMSGMSAPSPSLPTPSSSLALEASLGQPSRLPLSG
DSEGHERETEPIPKMKVMESPRKAPGSTSGTSQDGNTKDARGNLGSLPLGKTRPGAVSPL
NSPLSTTFPSPFGKEAFPPSSPLQKGGSFWSSIPASPASRPSSFTFPGDSDSLQRQTHRH
AAPSKDTDRMSTCSSASEQSVQSTQSNGSEGSSSSNISTMLVTHEYTAVKEDEINVYQGE
VVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIMENPDGTLKKSTSWHTAL
RLRKKSEKKDKDGKRDGKLENGYRKPREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTC
ETGETVVFRCRVCGRPKASITWKGPEHNTLNNDDHYSISYSDIGEATLKIIGVSTEDDGI
YTCIAVNDMGSASSSASLRVLGPGSDGIVVTWKDNFDAFYSEVAELGRGRFAVVKKCDQK
GTKRAVATKFVNKKLMKRDQVTHELGILQNLQHPLLVSLLDTFETPTSYVLVLEMADQGR
LLDCVVRWGSLTEGKVRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDQSLAKPTIKLAD
FGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTADTWSVGVLTYVLLSGVSPFLDDS
VEETCLNICRLDFSFPEDYFQGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGS
GKGTGVLDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
NT seq 9312 nt   +upstreamnt  +downstreamnt
atgagcggcagcagcggcggtgccaccgccccggccgcgtcctccggccccgcggcagcg
gccagcgcggcgggctccggctgcgggggcggcgccggcgagggcgccgaggaggccgcc
aaggacctagccgacatcgcggccttcttccgatccgggtttcggaaaaatgatgaaatg
aaagctatggatgttttgccaattctgaaggaaaaagtcgcctatctttcaggtggtaga
gataagcgtggaggtcccattttaacatttccagcccgcagcaatcatgacagaatacgg
caggaggacctcaggaggctcatttcctatttagcctgcattcccagtgaggaagtctgc
aagcgagggttcacagtgattgtggacatgcgcggctccaagtgggactccatcaagccg
ctgctgaagatcctgcaggagtcctttccgtgctgcatccacatagccctgataatcaag
cccgacaacttctggcagaaacagaggacgaattttggcagctccaaatttgaatttgag
acaaatatggtctccttagaaggccttaccaaagtagttgatccttcccagctaactccc
gagtttgacggctgcctggaatacaaccatgaggagtggatagaaatccgagtagctttc
gaggagtacattagcaatgcagcccatatgctgtcacggctagaggaacttcaggatgtt
ctcgccaaaaaggagttgcctcaggacctagagggggctcggaacatgatcgacgagcac
tcccagttgaagaagaaggtgatcaaggcccccattgaggacttggacttagaagggcag
aagctgcttcagcggatacagagcagcgacagtttccccaaaaagaactcaggctcgggc
aatgcagacctgcagaacctcctgcccaaggtgtccaccatgctagacaggctgcactcc
acccggcagcacctccaccagatgtggcacgtgaggaaactgaagctggaccagtgcttc
cagctgcggctgttcgaacaggatgctgagaagatgtttgactggatcactcacaacaaa
ggcctgtttctgaacagctacacggagatcgggaccagccacccgcatgccatggaactt
cagacgcagcacaatcattttgccatgaactgtatgaacgtatatgtaaatataaaccgc
ataatgtcagtggccaatcgcctggtggagtcgggccactacgcctctcagcagattaag
cagattgcaaatcagctggaacaagagtggaaggcgtttgcagcagccttggacgagcgc
agcaccttgttggacatgtcctccatctttcaccagaaggctgagaagtacatgagcaac
gtggactcgtggtgtaaggcctgtggtgaagtagaccttccctcggagctgcaggacctg
gaagacgccattcatcatcaccagggcatctacgagcacatcaccctcgcctactcagag
gtgagccaggatgggaagtccctccttgataagctccagcgccccctgacccccggcagc
tccgactccctcaccgcctccgccaactactccaaggctgtgcaccacgtcttggatgtc
atccacgaggtcctgcaccaccagcgccagctggagaacatctggcagcaccgcaaggtt
cggctccaccagaggctgcagctctgcgtcttccagcaggacgttcagcaggtgctggac
tggatagagaaccacggagaagcgtttctgagcaaacacacgggcgtgggcaaatccctt
caccgggccagagctttgcagaaacgccacgaggacttcgaggaagtcgcacagaacacg
tacacaaacgcagataaactgctagaagcagcagagcagctggctcagacgggggaatgt
gaccccgaagagatttatcaggctgcccatcagcttgaagaccggatacaagattttgtt
cggcgagttgaacaacgaaagatcctgctggacatgtctgtgtcatttcacacgcacgta
aaagagctctggacatggctggaggagttacagaaggaactgctggacgacgtgtacgcc
gagtcggtggaggccgtgcaggacctcatcaagcgattcggccagcagcagcagaccacc
ctgcaggtgactgtcaacgtgatcaaggaaggagaagacctcatccagcagctgagggac
tccgccatctccagtaacaaaactccgcacaacagttccatcaaccacatcgagacggtg
ctacagcagctggacgaggctcagtcccagatggaggagctcttccaggagcgcaagatc
aagctggagctcttcctgcagctgcgcatcttcgagcgggatgccatcgatatcatctcg
gaccttgagtcgtggaatgatgagctttcccagcaaatgaatgacttcgatacggaggac
ctgacgatcgcagagcagcgcctacagcaccatgcagacaaagccctgaccatgaataac
ttgactttcgatgtcatccaccaaggacaggatcttctgcagtatgtcaatgaggtccag
gcctctggtgtggagctgctttgtgacagagatgtggacatggccactcgggttcaggac
ctcctggagtttcttcatgagaagcagcaggagttggatttggcagctgagcagcatcgg
aaacacttggagcagtgtgtgcagttgcgccacctgcaggcggaagtgaagcaggtgctg
ggctggatccgaaatggagagtccatgctaaatgctgggctcatcacggccagctcgctg
caggaagccgagcagctgcagcgagaacacgagcagttccagcatgcgattgagaaaacg
caccagagcgcgctgcaggtacagcagaaggcggaggccatgctgcaggccaaccactat
gacatggacatgatccgggactgtgcagagaaggtcgcctcgcactggcagcagctcatg
ctgaagatggaagaccgcctcaagcttgtcaatgcctctgtcgccttctacaagacttct
gagcaggtctgcagtgtcctggaaagtctggaacaggagtacaagagagaagaggactgg
tgtggcggggccgacaagctgggccccaattctgagactgaccacgtcacccccatgatt
agcaagcacctcgaacaaaaggaagccttcctgaaggcttgcacactggccaggaggaac
gcagacgtcttcctaaagtacctgcacaggaacagcgtgagcatgccggggatggtgacg
cacatcaaagctccggaacagcaagtaaaaaatatcttgaatgaactcttccagcgggaa
aacagggtattgcattattggaccatgaggaaaaggcggctggaccagtgtcagcagtac
gtggtcttcgagaggagcgccaagcaggcattagagtggatccacgacaatggggagttc
tacctttccacacatacctcaacagggtccagcattcagcacacacaggagctgttgaaa
gaacacgaggagtttcagataactgccaagcaaaccaaagagagggtgaagctattgata
cagctggccgatggcttttgtgaaaaagggcatgcccatgcagcagaaattaaaaaatgt
gtgaccgcagtggataagaggtacagagatttctctctgcgcatggagaagtaccggacc
tctttggagaaagccctggggatttcttcagattccaacaaatcgagtaaaagcctgcag
ttggacatcatccctgccagtatccccgggtcagaggtgaagcttcgggatgctgcccac
gagcttaatgaagagaagcggaagtctgcccgcaggaaagagttcatcatggctgaacta
attcaaacggaaaaggcttatgtcagagacctccgagagtgtatggatacctacctgtgg
gaaatgaccagcggcgtggaggagatcccgccaggcattgtcaacaaggagctcatcatc
ttcgggaacatgcaggagatctacgagttccacaacaacatcttcctgaaggagctggag
aagtacgagcagctcccagaggacgtgggacactgcttcgtcacctgggcagacaagttt
cagatgtatgtcacatactgcaaaaataaacctgattctacacagctgatactagagcac
gcagggtcctactttgatgagatccagcagcggcatggcttagccaattccatctcttcc
tacctgatcaaaccagttcagcggataacaaagtatcagctccttttaaaggagctgctc
acatgctgtgaggaaggaaagggggagatcaaagatggcctggaggtgatgctcagcgtg
cccaagcgagccaatgatgccatgcacctcagcatgctggaagggtttgacgaaaacatt
gagtctcagggagagctcatcctgcaggagtccttccaagtgtgggacccgaaaacctta
attcggaagggtcgagaacggcatctcttcctttttgaaatgtccttggtgtttagtaaa
gaagtgaaagactccagcgggagaagcaagtacctgtacaaaagcaagctgtttacctca
gagttgggtgtcacagaacacgttgaaggagatccttgcaaatttgcactgtgggtgggg
aggacgccaacttcagataataaaattgtccttaaggcatccagtatcgagaacaagcag
gactggatcaagcacatccgtgaggtgatccaggagaggacggtgcacctgagaggagcc
ctgaaggagcccattcacatccccaaaacagctccggcagcaaggcagaaggggaggagg
gatggagaagacctggacagccaaggggatggcagcagccagcccgacaccatttccatc
gcctccaggacatctcagaacacactggacagtgataagctttctggtggctgcgagctg
acggtcgtgattcatgacttcacagcctgcaacagcaatgagctgaccatccggcgtggc
cagacagtggaggtcctggaacggcctcacgacaagcccgactggtgtctggtgcgcacc
actgacaggtcccctgcagcagaaggcctcgtgccctgtggctcactgtgcatcgcccac
tcccgaagtagcatggagatggagggcatcttcaaccacaaagactcactgtcggtctcc
agtaatgacgccagcccaccggcctctgtggcttcccttcagccccacatgatcggagca
cagagttcaccaggtcccaagcggcccggcaacaccctgcgcaagtggctcacgagcccc
gtgcggcggctcagcagcggtaaggccgatgggcatgcgaagaagctggcccacaagcac
aagaagagccgggaggtccgtaagagcgcggatgctggatcgcagaaggattcggatgac
agcgctgccaccccgcaggatgaaaccatcgaagagagaggacggaacgagggtctcagc
agtggtacgctgtccaagtcctcgtcctcgggcatgcagagctgcggagaagaagaaggc
gaggagggcgccgacgctgtaccactgcctccccccatggccattcagcagcacagcctc
cttcagccggactcgcaggatgacaaggcctcttcaaggttattggtccgccccaccagt
tctgagactcccagcgcagctgagctcgtcagtgctattgaagaactcgtgaaaagcaaa
atggcactggaggatcgtcccagctcgctgctcgtcgaccagggagacagtagcagccca
tccttcaatccctcagacaattccctcctctcatcctcctcacccattgatgagatggaa
gaaagaaaatgcagctctctgaagagaaggcactatgttttgcaagagttagtggagaca
gagcgagactatgtacgggaccttggctgtgtggttgagggctacatggcacttatgaag
gaagacggcgttcctgatgacatgaagggaaaagacaagatcgtgtttggcaacatccat
cagatttatgactggcacagagacttttttttaggagagttggagaagtgccttgaagat
ccagaaaaactcggatccctttttgtaaagcacgagagacggttgcacatgtacatagtt
tattgtcaaaataagccaaagtctgagcacattgtgtccgagtacatcgacacctttttt
gaggacttaaagcagcgcctgggccacagactgcagctcactgatctgttgatcaaaccg
gtgcagagaatcatgaagtaccagctgctcctgaaggacttcctcaagtactcaaaaaaa
gctagcctggacacatccgaattagagaaagctgtagaagtcatgtgcatcgtgccgaag
cgctgtaatgacatgatgaacgtcgggcggctgcagggatttgacggtaaaattgttgcc
cagggtaaactgctcttacaggacacattcctggtcacagatcaagacgcaggacttctg
cctcgatgcaaagagaggcgggttttcctctttgaacagatcgtcatattcagcgaacca
cttgataaaaaaaagggcttttccatgccaggatttctgttcaagaacagtatcaaggtg
agttgcctctgcttggaggaaaatgtggagagcgatccctgtaagttcgccctgacgtcc
aggacgggcgatgccgtggagactttcgttttgcattcatccagtccaagcgtccggcaa
acgtggatccatgagatcaaccaaatcttagaaaaccagcgcaactttttaaacgccttg
acatcacccatcgagtaccagaggaaccatagtgggggcggcggcagtggcagcgggggc
agcagcggcgggggcgggggcagcggcggcagcggggcctccagcggaggcagcagcagc
catggcagtggccccagcagctgtagcagtggccccagctcgagcaggagcaggccctcc
aggatcccacagcctgtcagacaccacccccccatgctggtctcctctgcagcctcaagc
caggcagaggcagacaagatgtcaggtatgtctgctcccagcccctcactgcctaccccc
agcagcagcctggcccttgaggccagccttggccagcccagcaggctccccctgagtgga
gactccgaaggtcatgagcgagaaacagaacccattcccaagatgaaggtgatggagagc
ccccggaaggccccggggagtacttccggtacaagccaagacggaaacaccaaggatgcc
cggggaaacctgggctcactgcctctgggcaagactagacctggggccgtctcaccgctg
aactctcctctctccactacgttcccttctccttttggcaaggaggcctttcctcccagc
agccccttgcagaaggggggctccttctggagctccattcctgcttcccctgccagccgg
ccaagctccttcaccttcccgggggacagtgactccctccagcgacagacgcaccgccat
gcagcccccagcaaggacacagaccgcatgagcacgtgctcctcggccagcgagcagtcc
gtgcagtccactcagagcaacgggagtgaaggcagcagcagtagcaacatctccaccatg
ctggtgacacacgagtacacggcagtgaaggaggatgagataaacgtctatcaaggagag
gtcgttcaaattctggccagcaaccagcagaacatgtttctggtgttccgagccgccact
gaccagtgccccgcagccgagggctggattccgggcttcgtcttgggccatacgagtgca
gttatcatggagaaccccgacgggactctcaagaaatcaacatcttggcacacagcactc
cgtttaaggaagaagtctgagaagaaagataaagacggcaaaagggatggcaagttggag
aatgggtacaggaagccacgagaagggctcagtaacaaggtatctgtgaagcttcttaac
cccaactacatttatgacgttcccccagaatttgttatcccattgagtgaggtcacgtgc
gagacaggggagaccgttgtttttagatgtcgtgtctgtggccgccccaaggcctcaatc
acctggaagggccccgaacacaacactttgaacaacgatgaccactacagcatctcctac
agtgacattggggaggccactctgaagatcattggtgtaagcacagaagatgatggcatc
tacacctgcatcgctgtgaatgacatgggttcagcctcatcttctgccagcctgagggtt
ctaggtccagggagtgatgggatcgtggtgacttggaaggacaacttcgacgccttctac
agtgaagtggctgagcttggcaggggcaggtttgctgtagttaagaaatgtgaccagaag
ggaaccaaacgagcagtggccacaaagtttgtgaacaagaagttgatgaagcgtgaccag
gtcactcatgagctcggcatcctgcagaacctgcagcaccccctcctcgtgagccttctt
gacaccttcgagacccccaccagttacgtcctggttctggaaatggctgaccaaggtcgc
ctccttgactgtgtggtccggtggggaagcctcaccgaagggaaggtcagagcgcacctg
ggggaagttctggaagccgtccgataccttcacaactgcaggatagcacacctggaccta
aagcctgagaatatcttggtggatcagagtttggccaagccaaccattaaactggctgac
tttggagacgctgtccagctcaacaccacctactacatccaccagttgctggggaacccc
gagtttgcagccccggaaatcattcttgggaaccctgtctccctgaccgcggacacatgg
agtgttggggtgctcacctacgtgctgctcagcggcgtgtcccccttcctggatgacagc
gtggaagagacctgcctgaatatttgccggctggactttagcttcccagaggactacttt
caaggagttagccagaaggccaaagaattcgtgtgcttcctcctacaggaggaccccgcc
aagcgtccctcggctgcactggccctgcaggaacagtggctgcaggcaggcaacggcagc
ggcaaaggcacgggcgtcctcgacacgtccagactgacctccttcattgagcggcgcaaa
caccagaatgatgttcgacctatccgtagcattaaaaacttcttacagagcaggcttctg
cctagagtttga

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (31)   
   RefSeq(nuc) (13)   
   GenBank (9)   
   EMBL (9)   
Protein domain (20)   
   Pfam (20)   
All databases (106)   

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