KEGG   Mus musculus (house mouse): 224020
Entry
224020            CDS       T01002                                 
Symbol
Pi4ka, PI4K-alpha, Pik4ca
Name
(RefSeq) phosphatidylinositol 4-kinase alpha
  KO
K00888  phosphatidylinositol 4-kinase A [EC:2.7.1.67]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu01100  Metabolic pathways
mmu04070  Phosphatidylinositol signaling system
Module
mmu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    224020 (Pi4ka)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    224020 (Pi4ka)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    224020 (Pi4ka)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.67  1-phosphatidylinositol 4-kinase
     224020 (Pi4ka)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Others
   EFR3-PI4KIII alpha complex and associated proteins
    224020 (Pi4ka)
 Endosome - Golgi transport
   Others
    224020 (Pi4ka)
SSDB
Motif
Pfam: PI4K_N PI3_PI4_kinase PI3Ka ABC1 PI4KB-PIK1_PIK
Other DBs
NCBI-GeneID: 224020
NCBI-ProteinID: NP_001001983
MGI: 2448506
Ensembl: ENSMUSG00000041720
UniProt: E9Q3L2 A0A140T8I9
Position
16:complement(17098215..17224178)
AA seq 2044 aa
MCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDCVVPYLLRLLRGLPKVYWVEESTA
RKGRGNLPVAESFSFCLVTLLSDVACRDPSLRDEILEAILQVLHVLLGMCQALEIQEKEY
LCKYAIPCLIGISRSFGRYSNSEESLLSKLFPKVSPHSLRIPEELEGVRRRSFNDFRSIL
PSNLLTVCQEGTLKRKTSSVSSISQVSPERGIPPPSSPGGSAFHYFEASCLPDGTALEPE
YYFSTISSSFSISPLFNGITYKEFCIPLEMLRELLNLVKKIVEEPVLKSLDAIVAGVMEA
NPSADLYYTTFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNMSQGELQKIL
HDADRIHSEMSPLKLRCQANAACVDLMVWAVKDEQGAENLCIKLSEKLQSKTSSKVIIAH
LPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGSDIKI
SVTNEHSESTLNVLPGKKNQPSMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNR
LYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIID
QLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAA
NIQEEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLT
RRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSK
EPLRSVLQYNSAMKNDTVTPAELSELRSTIINLLDPPPEVSALINKLDFAMSTYLLSVYR
LEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTK
ENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLS
LSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKS
HLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLTERPACVKKDYSN
FMASLNLRNRYAGEVHGMIRFSGATGQMSDLNKMMVQDLITALDHSHPQHYTQAMFKLTA
MLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWHM
TVEQKFGLFSVETKEADPLAASEASQPRPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVE
IFSSLLQRSMSLNIGGARGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKI
YSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNL
DITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLAT
EIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQL
PARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPP
TGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAA
KSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFF
NKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSA
AKAPYLAKFKVKRCGVSELEKEGLQCRSDAEDECFSQEADGKKICWQAAIFKVGDDCRQD
MLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYD
YFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGF
MFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLV
TLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQNCFLSNRSRTYDMIQYYQN
DIPY
NT seq 6135 nt   +upstreamnt  +downstreamnt
atgtgcccagtagattttcatggaatcttccaactagatgaaagacggagagatgcagtg
attgcattgggcatttttctcattgaatctgatcttcagcacaaagattgtgttgttcct
tatcttcttcgacttctcaggggtcttccaaaagtgtattgggtagaagaaagcacagct
cggaaaggcagaggtaacctcccagttgcagagagcttcagcttctgcctggtgaccttg
ctgtctgatgtggcttgcagggacccctcacttagggatgagattttagaggcaattttg
caggttttacatgtccttttgggaatgtgccaggccttggagattcaagaaaaagaatac
ctttgcaagtatgcgatcccatgcctgataggaatctcaagatcttttggacgttacagc
aattcagaagagtctctcctctcaaagcttttccccaaagtttctcctcattccctgaga
atcccagaagagctagaaggtgtccgaaggcgttcctttaatgactttcgctccatcctg
cccagcaacctgctaactgtctgtcaggagggcacactgaagaggaaaaccagcagtgtg
tccagcatctctcaggttagcccagaacgtggcataccccctcccagctcccctggagga
tctgcatttcactattttgaagcttcttgcctacctgatgggactgccttggagcctgaa
tactacttctctaccatcagctccagtttttctatctctcccctgttcaatggtattacc
tataaggagttctgtattccactggaaatgcttcgggaactcttaaacttggtgaagaag
attgttgaggagcctgttctcaaatccttagatgcaattgtagccggcgtgatggaggcc
aatcccagtgctgatctgtactatacaaccttcagtgatcccctgtacctgaccatgttc
aagatgcttcgagatactctgtactacatgaaagatctgcccacttcctttgtgaaagag
atccatgattttgtgttggagcagttcaacatgagccaaggggagctccaaaagattctg
catgacgcagataggatccacagtgagatgagcccactcaaactgcgctgccaagcaaac
gctgcctgtgtggacctcatggtgtgggctgtgaaggatgagcagggtgcagaaaacctt
tgcatcaagctgtctgaaaagctgcagtccaagacatccagtaaggtcatcattgcccat
ttgcccttgctgatctgctgcctacagggtctgggccgcctgtgtgaaaggttcccagtg
gtggtccactcagtgacgccatctttgagagactttctggtaattccatccccagtgctg
gtgaagctctataagtaccacagtcagtaccacacagttgctggcagtgatataaaaatc
agtgtcaccaatgagcattccgagtcaactctgaatgtcttgccgggcaagaagaaccag
ccatccatgtatgagcagctccgagacatcgccattgacaacatctgcaggtgcctgaag
gccggcctcaccgtggaccctgtgatcgtggaggccttcctggccagcctctccaaccgg
ctctacatttcccaggagagtgacaaggatgctcacttgattcctgaccataccatccgt
gccttgggacacattgcagtagctttgagggacactccaaaggtcatggagccaattctg
cagatcctgcagcagaaattttgccagcccccctcaccccttgatgtgctcatcatcgac
cagctgggctgcctggtgatcactggaaatcaatacatttatcaggaagtgtggaatctc
ttccagcaaatcagtgtaaaggccagttcagttgtgtattcagccaccaaagactataaa
gaccatggctacaggcactgctccctagcagtgatcaatgccctggccaacattgcagcc
aacattcaggaggagcatcttgtggacgagctgttgatgaacctgctggaactgtttgtg
cagctggggctggaggggaaaagagccagtgagagggccagtgaaaaggggcctgccctg
aaggcttccagcagtgcaggaaatttgggcgtgctcattcctgtaatagctgtgctcacc
cgacgattgccacccatcaaagaagctaaacctaggctacagaagcttttccgagatttc
tggctctactctgtgctaatgggattcgctgtggaaggctcaggactctggccggaagag
tggtatgagggagtctgtgaaatagctaccaagtcacctctgcttacctttcccagcaaa
gagcctctgcgatcagtcctccagtacaattcagctatgaaaaacgatacggtcacccct
gctgaactgagtgagctccgaagtaccatcatcaacttgctagatcctcctcctgaggtg
tctgccctcatcaacaagctggactttgccatgtctacctatctcttgtctgtgtatcgg
ctggagtacatgagggtactgcgttctacagatccagatcgcttccaggtaatgttctgc
tactttgaggataaagctattcaaaaagacaaatctgggatgatgcagtgtgtcattgct
gttgctgacaaagtgtttgatgctttcctgaacatgatggcagaaaaagctaagaccaag
gagaatgaagaggagctggagcggcatgcacagtttctgctggtgaacttcaaccacatt
cataagaggataaggagagtagctgacaaatacctatctggtctggtggataagtttcca
cacttgctctggagcgggactgtgctgaagaccatgttggacatcctgcagaccctgtca
ctatcactaagtgctgatattcacaaggaccaaccttactatgacattcctgatgccccc
tatcggatcacggttcctgacacatacgaagcccgggagagcatcgtgaaagactttgct
gcgcgctgtggaatgatcctacaggaagccatgaagtgggcacccacggtcactaagtcc
cacctacaggaatatctgaacaagcatcagaactgggtgtcaggactgtctcagcacaca
ggattggccatggccactgagagcatccttcattttgccggctacaacaagcagaacaca
actcttggggcaactcagctaactgagcgtccggcctgtgtgaagaaagactactccaac
ttcatggcatccttgaatttgcgcaaccgctatgccggcgaggtacatggaatgattcgg
ttctcaggtgccacaggccagatgtctgacctgaacaaaatgatggtccaagatctgatc
acagctttggaccacagtcatcctcagcactatacacaagccatgttcaaattgacggca
atgctcattagcagcaaagattgtgatccacagctccttcatcatctgtgttggggtccc
ctccgaatgttcaatgagcatggcatggagactgcactagcctgctgggagtggctgctg
gctggcaagaatggagtggaagtgccgtttatgcgggagatggcaggagcctggcacatg
acagtagagcagaagttcggcctcttttctgtggaaacaaaggaagcagaccccctggca
gcatcagaagcaagtcagccaagaccttgtccccccgaagtgacacctcactacatctgg
atcgatttcctggtccagcggtttgagattgccaagtactgtagctctgaccaggtggag
atcttctcaagcctgctgcagcgctccatgtccctcaatattggtggagccagggggagc
atgaacaggcatgtggcagccattggaccacgtttcaaactgctgaccttggggctgtcc
ctcctgcatgctgatgtggttccaaatgcaaccattcgaaacgtgcttcgagagaagata
tactcaacagcctttgactatttcagttgtccaccaaagtttcctactcaaggagaaaag
aggcttcgtgaagatataagcataatgattaagttttggactgccatgttctcagataag
aagtacctgactgccagccagctcgttcccccagataatcaggacacccgaagcaacttg
gatataactgtgggctctcgacaacaggctacccagggctggatcaacacttaccccctc
tccagtggcatgtcaaccatctccaaaaagtcaggtatgtctaagaaaaccaaccggggc
tcccagctgcacaagtactacatgaaacgcaggacactgctgctgtcactattggccact
gagatcgaacgcctcatcacttggtacaacccactgtcagccccagagctagagctggac
caggcaggagagaacagcgttgccaactggaggtccaagtacatcagcttgagtgagaag
cagtggaaggacaacgtgaaccttgcctggagcatctctccatacctcgctgtgcagctg
ccagccaggttcaagaatacagaagccattggaaatgaagtgacccgtctcgttcgcttg
gatcctggagctgttagtgatgtccctgaagccatcaagttccttgtcacctggcacacc
atcgatgctgatgctccagagctcagccatgttttatgctgggcacccacggacccacct
acaggcctctcctacttctccagcatgtacccaccacaccctctcactgcacagtatggg
gtaaaagtcctgcgatccttccctccggatgccattctgttctacatcccccagattgtg
caggccctcagatatgacaagatgggctatgtgcgtgagtacattctctgggctgcagcc
aaatcccagcttctggcacaccagtttatttggaacatgaaaactaacatctaccttgat
gaagaagggcaccagaaagaccctgacatcggtgacctcctggagcagttagtagaagag
atcacagggtctctatcaggcccagccaaagatttctatcaacgggaatttgatttcttt
aacaagatcacaaacgtgtcagccatcatcaagccctaccctaaaggcgatgaaaggaag
aaggcttgtctgtcagctctgtctgaagtgaaggtgcagcctggctgctacctgcccagc
aaccctgaagcaatcgtgctagacattgactacaagtcagggacaccaatgcagagtgcc
gcaaaagcgccgtatctggccaagtttaaggtgaagagatgcggagtgagtgaacttgaa
aaagaaggtctgcagtgccgctcagacgcagaggatgaatgcttcagccaagaggctgat
ggcaagaagatctgctggcaagcagccatcttcaaagtgggggatgactgccgacaggac
atgttagccctgcagatcatcgacctcttcaagaacatcttccagctggttggcctggac
ctcttcgtttttccttatcgggtagtggctactgcccctgggtgcggagtgattgagtgc
atcccagactgtacctcccgggaccagctgggccgccagactgactttggcatgtatgac
tactttacacgccagtatggggatgagtctaccttggccttccagcaggcacgctacaac
tttatcagaagcatggccgcctatagcctcctgctgttcctgctgcagatcaaggacagg
cacaatggcaacatcatgctggacaagaaggggcacatcatccacatcgactttggcttc
atgtttgaaagctcaccgggtggcaaccttggctgggaaccagacatcaagctgacagac
gagatggtgatgattatggggggcaaaatggaagccacacccttcaagtggttcatggag
atgtgtgtccgaggttatctggctgtgcgcccctatatggatgcagtcgtctccctggtt
acactcatgttggacacaggcctgccctgttttcgtggccagacaatcaaacttttgaaa
cacaggttcagcccgaacatgacagagcgggaggctgcgaattttatcatgaaggtcatc
cagaactgtttcctcagcaacaggagccggacctacgacatgatccagtactaccagaat
gatatcccctactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
Protein domain (5)   
   Pfam (5)   
All databases (88)   

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