KEGG   Mus musculus (house mouse): 22436
Entry
22436             CDS       T01002                                 
Symbol
Xdh, XO, Xor, Xox-1, Xox1
Name
(RefSeq) xanthine dehydrogenase
  KO
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu00232  Caffeine metabolism
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01232  Nucleotide metabolism
mmu04146  Peroxisome
Module
mmu_M00958  Adenine ribonucleotide degradation, AMP => Urate
mmu_M00959  Guanine ribonucleotide degradation, GMP => Urate
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    22436 (Xdh)
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    22436 (Xdh)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    22436 (Xdh)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    22436 (Xdh)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    22436 (Xdh)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.1  With NAD+ or NADP+ as acceptor
    1.17.1.4  xanthine dehydrogenase
     22436 (Xdh)
   1.17.3  With oxygen as acceptor
    1.17.3.2  xanthine oxidase
     22436 (Xdh)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   22436 (Xdh)
SSDB
Motif
Pfam: MoCoBD_1 MoCoBD_2 FAD_binding_5 Ald_Xan_dh_C Fer2_2 CO_deh_flav_C Fer2
Other DBs
NCBI-GeneID: 22436
NCBI-ProteinID: NP_035853
MGI: 98973
Ensembl: ENSMUSG00000024066
UniProt: Q00519 Q9CVF2
Position
17:complement(74190890..74257191)
AA seq 1335 aa
MTRTTVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISK
YDRLQNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTKKLHPVQERIAKSHGSQCGFCTP
GIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPN
CCMSQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQ
VSTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGIS
FGAACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPI
SDLNPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFF
SAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSW
NEELLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGK
LDPTFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIP
RYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAK
DEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKG
DLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIA
KMLGVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITG
GRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGT
GRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQ
KLEGFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQG
GALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPT
AASASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPN
LGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG
AFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASK
AVGEPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLC
ATGTPENCKSWSVRI
NT seq 4008 nt   +upstreamnt  +downstreamnt
atgacgaggacaacggtagatgagttggtcttctttgtgaatggcaaaaaggtggtggag
aaaaatgcagaccctgaaacaacacttctggtctaccttagaagaaagttggggctgtgc
gggaccaagcttggctgtggagaaggtggctgtggggcatgcaccgtgatgatctccaag
tatgaccgccttcagaacaagatcgttcatttttccgtcaatgcctgcttgacccccatc
tgctccttgcatcatgttgctgtgacaactgtggaaggcataggaaacaccaagaagctg
catcctgtccaggagagaattgccaaaagccatggttcccagtgtgggttctgtacccct
ggtattgtcatgagtatgtacacactgctccgaaacaagcctgagcctactgtcgaggag
atcgagaatgccttccaaggaaacctctgccgctgtacaggctatagacccatcctccag
ggattccggacctttgccaaggatggtgggtgctgtggaggaagtggaaacaacccaaac
tgctgcatgagccaaacaaaggaccagacgattgctccctcatcttctttattcaacccg
gaggatttcaaacctttagatcccacccaagagcccatctttcccccagagttgctgagg
ctgaaagacactccccggaagacgttgcgttttgaaggggaacgtgtgacctggatccag
gtttcaaccatggaggaactgcttgacctcaaagcccagcaccctgatgccaagctggtg
gtgggaaacacagagataggcattgaaatgaaatttaaaaatatgctatttcctctgatc
atctgcccagcctggatccttgaactgacctcagtggcacatgggcctgagggaatctcc
tttggagccgcttgcccccttagcttggtggaaagtgtcctggcggacgcgattgctaca
cttccagagcagaggacagaggtgttcagaggcgtgatggagcagctgcgctggtttgct
ggcaagcaggtcaagtccgtggcgtccattggcgggaacatcatcaccgcgagccccatc
tctgacctcaaccctgtgctcatggccagtcgagccaagctgaccctcgcatctagaggt
accaagagaacggtctggatggaccataccttcttccctggctatagaaggactctgctc
agtccagaggagatattggtgtccattgtgatcccctacagcaggaagggtgagtttttc
tcagccttcaagcaggcctccaggagagaagatgacattgccaaggtgaccagtggcatg
agagtcctgttcaagccagggaccactgaagtgcaggaactgtccctttgctttggaggg
atggctgacagaactgtctcagccctcaagaccactccgaagcagctgtccaagtcctgg
aatgaggagttgctgcaggatgtgtgtgctggcttggcagaggagctgcacctggccccc
gacgcccctggtgggatggtggaattccggcgcaccctcaccctcagcttcttcttcaag
ttctacctgacagtgcttcagaagctgggcagagcggaccttgagggtatgtgtggtaaa
ctggaccccacctttgccagcgccaccctgctctttcagaaggatcctccagctaacgtc
cagcttttccaagaggtgcccaagggtcagtctgaggaggacatggtgggcaggcccatg
cctcacctggcagcagacatgcaggcatccggggaggctgtgtactgtgatgacattccc
cgctatgagaatgagctgtccctcaggctggtcaccagcacgcgggcccatgctaaaatc
atgtccatcgacacttcagaagccaagaaggtgccagggtttgtttgtttcctcacctca
gaggatgtccctggtagtaacataactggcattttcaatgatgaaactgtctttgcgaag
gatgaggttacttgtgttgggcacatcattggtgctgtggtcgctgacaccccagaacat
gcacacagagccgctagaggggtgaaaatcacctatgaagaccttccagccattatcaca
atccaggatgctataaagaacaactccttttatggccccgaggtaaaaatcgagaaagga
gatctcaagaaaggcttttctgaagctgacaatgttgtctcaggagaattatatattggt
ggccaggagcacttctatctggagacccactgcaccattgccgtgccgaaaggcgaggca
ggcgagatggagctcttcgtgagcacacagaacaccatgaaaacccagagctttattgca
aagatgttgggtgttccagacaacagaattgtagtccgagtgaaaagaatgggtggaggc
tttggagggaaggagacccggagcactctgatatccacagcagtggccttggctgcatac
aagacaggccgccctgtacgttgcatgctggaccgagacgaggacatgctcataactggt
ggcagacatcccttcctggctaaatacaaggtgggcttcatgaagactgggactatagtg
gcactggaggtggctcacttcagcaatggcgggaacagtgaggatctctctcggagtata
atggaaagagctgtattccacatggacaacgcctataagatccccaacattcgcggcacc
gggaggatttgtaagactaatctgccctctaacacagccttcagaggctttgggggtcct
caggggatgctaatcgcagaatactggatgagtgaggtcgctgtcacctgtgggctgcct
gcagaggaggtacggaggaaaaacatgtacaaagaaggggacctgactcacttcaaccag
aagctggaggggttcaccttgcccaggtgctgggatgagtgcatagcgagctcccagtat
caggctcgcaagatggaagtggagaaattcaacagggagaactgttggaaaaagagaggg
ctgtgtataatcccgactaagtttggaataagcttcacactttcttttctgaaccagggg
ggtgccttggtccacgtgtacacggatgggtcggtgctgctgacacatggaggtactgag
atgggtcaaggccttcacaccaagatggttcaggtggccagcagagctctgaaaatcccc
acttccaagatccatataacggagacaagcactaacactgtccctaacacctctcccacg
gctgcctctgccagcgctgacctcaatggccaggccatttatgaagcctgtcagaccata
ctgaaaagactggagcccttcaagaaaaagaatccctcaggctcctgggagagctgggtc
atggatgcctacactagtgcagtgagcttgtctgctactggattttataagacacccaac
cttggttacagctttgagacaaactctgggaaccccttccactacttcagttatggggtg
gcttgctcagaagtagaaattgactgcttaacaggggaccataagaatctccgtacagat
atcgtcatggatgttggttccagcttgaatcctgccattgatatcggacaggtagaaggg
gcatttgtccagggtcttggtcttttcaccatggaggagctgcactactctcccgagggg
agcctgcacactcgtggccccagtacctacaagatccctgcatttggcagcatccccatt
gagttcagagtatccctgctccgcgactgccccaacaagagggccatctatgcatccaag
gctgtcggcgagccacctcttttcctggcttcttcgatcttctttgccatcaaagatgcc
atccgcgcagctcgagctcagcacggagacagtaacgccaaacagctcttccagctagac
agccccgccactccggagaagatccgaaacgcttgtgtggatcagttcaccaccctgtgt
gccactggaacaccagaaaactgtaaatcctggtccgtgaggatctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (2)   
   KEGG REACTION (13)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (41)   
   RefSeq(nuc) (3)   
   GenBank (19)   
   EMBL (19)   
Protein domain (7)   
   Pfam (7)   
All databases (132)   

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