KEGG   Mus musculus (house mouse): 225876
Entry
225876            CDS       T01002                                 
Symbol
Kdm2a, 100043628, 5530401A10Rik, Cxxc8, Fbl11, Fbl7, Fbxl11, Gm4560, Jhdm1, Jhdm1a, lalina
Name
(RefSeq) lysine (K)-specific demethylase 2A
  KO
K10276  F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03083  Polycomb repressive complex
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    225876 (Kdm2a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    225876 (Kdm2a)
   04121 Ubiquitin system [BR:mmu04121]
    225876 (Kdm2a)
   03036 Chromosome and associated proteins [BR:mmu03036]
    225876 (Kdm2a)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.27  [histone H3]-dimethyl-L-lysine36 demethylase
     225876 (Kdm2a)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    225876 (Kdm2a)
Ubiquitin system [BR:mmu04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Target recognizing subunit (F-box)
     225876 (Kdm2a)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   Histone demethylases
    225876 (Kdm2a)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.1)
     225876 (Kdm2a)
SSDB
Motif
Pfam: PHD_4 zf-CXXC F-box-like JHD F-box JmjC Cupin_8 LRR_4 Cupin_1
Other DBs
NCBI-GeneID: 225876
NCBI-ProteinID: NP_001001984
MGI: 1354736
Ensembl: ENSMUSG00000054611
UniProt: P59997 F6YRW4
Structure
Position
19:complement(4366172..4448749)
AA seq 1161 aa
MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLQTNKYNANFVTFMEGK
DFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIE
MTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKES
QTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHN
LELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFL
HSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLS
MDMELNELESGNGDEEGVDREARRMNNKRSVLTSPVANGVNLDYDGLGKACRSLPSLKKT
LSGDSSSDSTRGSHNGQVWDPQCSPKKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPT
GIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKP
HTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRM
KQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEG
LLNEELPNCWECPKCYQEDSSDKAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPT
SMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNP
SGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRPNPRVLMQHC
PARNPQHGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSV
FRYLSRKELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSW
TNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRD
LLTPPTDKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQS
SNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFI
SDLSINSLYCLSDEKLIQKIS
NT seq 3486 nt   +upstreamnt  +downstreamnt
atggaacctgaagaagaaaggattcggtacagccagagattgcgtggtaccatgcgtcgt
cgctatgaagatgatggcatttcagatgatgaaattgaagggaaaagaacttttgacttg
gaagagaagctccaaaccaacaaatataatgccaattttgttacttttatggagggaaaa
gattttaatgtagagtatatccagcggggtggcttgagagaccctctcattttcaagaat
tctgatggacttggaataaagatgccggatccagacttcacagtgaatgatgtcaaaatg
tgtgtggggagtcgtcggatggtggatgtcatggatgtgaacacacagaaggggattgaa
atgaccatggcacaatggacacgatactatgagactccagaggaagagcgagaaaaactc
tataatgttatcagcctagagtttagccacaccaggcttgagaatatggtgcagcggcct
tccacggtggatttcattgactgggtagataacatgtggccaaggcacttgaaagaaagt
cagacagaatcaacaaatgccatcttagagatgcagtaccctaaagtgcaaaagtactgt
ctaatgagtgttcgaggctgctatactgacttccatgtggattttggaggtacttctgtt
tggtatcacatccaccaaggtggaaaggtcttctggctcatcccccctacagcccacaac
ctggagctgtacgagaattggctgctatcagggaaacagggagacatctttctgggtgac
cgggtgtcagattgccaacgaattgagctcaagcagggctataccttcgttattccctca
ggttggattcatgctgtgtatactcctacagacacattagtgtttggaggcaattttttg
catagcttcaacatccccatgcaattaaagatatacagcattgaagatcgaacacgggtt
ccaaataaattccgttacccattttactatgaaatgtgttggtatgtgttggagcgctat
gtatactgcataaccaaccgatcccacctaactaaggattttcagaaagaatcccttagc
atggatatggagttaaatgagttggagtctggaaatggtgatgaggaaggggtggacaga
gaagcccgacgcatgaacaataagcgatctgtgcttaccagccctgttgctaatggagtg
aacctggattacgatggacttggcaaagcctgccgaagtcttccaagtctgaagaaaact
ttgtctggagactcatcctcagactctacccggggatcccacaatggccaagtttgggat
ccccaatgtagccctaaaaaggataggcaagtgcatctcacccattttgaacttgaaggt
cttcgatgtcttgtagataagttagagtcactgccactgcacaagaagtgtgtccccaca
ggaatagaagacgaagatgctctgattgctgatgtaaagattttgctggaagaacttgcc
agtagcgatcccaagttagccctcactggagtccctatagtacagtggccaaaaagggat
aagcttaaattccctaccaggccaaaggtgagggttcctacaattcccatcacaaagcct
cacaccatgaagccagctccacgcttaacacctgtaaggcctgctgcagcctcccccatt
gtgtcaggagccaggcggagaagagtgcggtgcaggaaatgcaaagcttgtgtgcaagga
gaatgtggagtctgccactactgcagggacatgaagaaatttggtggacctggacgcatg
aagcaatcctgtgtcctccgacagtgcttagcacccagactgcctcattcagttacgtgt
tctctctgtggagaagtagatcagaatgaagagacccaggactttgaaaagaaactcatg
gaatgctgcatctgcaacgagatagttcatcctggctgcctccagatggatggagagggg
ttgctgaacgaggaattgccaaattgctgggagtgtccaaagtgttaccaggaagacagc
tcggacaaagcccagaagcggaaaatagaagagagtgatgaagaagctgtacaagccaaa
gtcttacggcccctgaggagctgcgaggagcctctcacacccccgcctcactcacctact
tccatgctgcagctcatccacgacccggtttctccccggggtatggtgactcggtcatcc
cctggggctggccccagcgaccaccacagtgccagccgtgatgaacgcttcaaacggcgg
cagttgctgcggctacaagccaccgagcgcaccatggtacgggaaaaggagaacaatccc
agcggcaaaaaggagctgtctgaagttgagaaagccaagatccggggatcgtacctcact
gtcactctacagaggcccaccaaagagctccacgggacatccattgtgcccaagctgcag
gccatcacggcctcctctgccaaccttcgccctaacccccgcgtgctaatgcagcactgc
ccagcccgaaacccccagcatggggatgaggaggggcttgggggagaggaggaggaagag
gaggaggaggaggaagatgacagtgcagaggaggggggtgcagccaggctgaatggccgg
ggcagttgggctcaggatggagacgaaagctggatgcagcgggaggtctggatgtctgtc
ttccgctacctcagccgcaaagaactttgtgaatgtatgcgagtgtgcaagacatggtat
aaatggtgctgtgataaacgactttggacaaaaattgacttgagtaggtgtaaggccatc
gtaccacaagctctcagtggtatcatcaagcggcagccagtaagcctcgacctcagctgg
actaacatctccaaaaagcagctgacatggctggtcaataggctgccaggattaaaagac
ctcctcctagcaggctgttcctggtctgcagtatctgccctcagcacttccagctgcccg
cttctcaggacccttgatcttcggtgggcagtaggaattaaagaccctcaaattcgggac
ttgctgactccacccacagataagccaggtcaagacaatcgaagcaaactccggaacatg
actgacttccggctggcaggccttgacatcacagatgctactctccgactcatcattcgc
cacatgccccttttgtctcgacttgacctcagtcactgcagtcaccttacagatcagtcc
tccaacctactaactgctgtcgggtcttccactcgatactcccttacagagctcaatatg
gcaggttgcaataaattgacagaccagaccctgttcttcctaaggcgaattgctaatgtc
accttgattgaccttcgaggatgcaaacagatcacgagaaaagcctgtgagcacttcatc
tcagacttgtccatcaacagcctctactgcctgtctgatgagaaactgatacagaagatt
agctaa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (29)   
   RefSeq(nuc) (3)   
   GenBank (13)   
   EMBL (13)   
3D Structure (8)   
   PDB (8)   
Protein domain (9)   
   Pfam (9)   
All databases (102)   

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