KEGG   Mus musculus (house mouse): 225887
Entry
225887            CDS       T01002                                 
Symbol
Ndufs8, CI-23kD, TYKY
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit S8
  KO
K03941  NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00190  Oxidative phosphorylation
mmu01100  Metabolic pathways
mmu04714  Thermogenesis
mmu04723  Retrograde endocannabinoid signaling
mmu04932  Non-alcoholic fatty liver disease
mmu05010  Alzheimer disease
mmu05012  Parkinson disease
mmu05014  Amyotrophic lateral sclerosis
mmu05016  Huntington disease
mmu05020  Prion disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05208  Chemical carcinogenesis - reactive oxygen species
mmu05415  Diabetic cardiomyopathy
Module
mmu_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    225887 (Ndufs8)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    225887 (Ndufs8)
  09159 Environmental adaptation
   04714 Thermogenesis
    225887 (Ndufs8)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    225887 (Ndufs8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    225887 (Ndufs8)
   05012 Parkinson disease
    225887 (Ndufs8)
   05014 Amyotrophic lateral sclerosis
    225887 (Ndufs8)
   05016 Huntington disease
    225887 (Ndufs8)
   05020 Prion disease
    225887 (Ndufs8)
   05022 Pathways of neurodegeneration - multiple diseases
    225887 (Ndufs8)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    225887 (Ndufs8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    225887 (Ndufs8)
Enzymes [BR:mmu01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     225887 (Ndufs8)
SSDB
Motif
Pfam: Fer4 Fer4_7 Fer4_21 Fer4_16 Fer4_6 Fer4_9 Fer4_8 Fer4_10 Fer4_2 Fer4_4 Fer4_17 Fer4_3
Other DBs
NCBI-GeneID: 225887
NCBI-ProteinID: NP_001258372
MGI: 2385079
Ensembl: ENSMUSG00000059734
UniProt: Q8K3J1 Q5M9P5 Q3UY05
Structure
Position
19:complement(3958863..3962774)
AA seq 212 aa
MYRLSSSMLPRALAQAMRTGHLNGQSLHSSAVAATYKYVNKKEQESEVDMKSATDNAARI
LMWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCE
AICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETH
EELLYNKEKLLNNGDKWEAEIAANIQADYLYR
NT seq 639 nt   +upstreamnt  +downstreamnt
atgtatcgcctgagctcatcaatgctgccacgggccttggcccaggccatgcgcacagga
catcttaatggacaaagccttcatagcagcgcagtggcggcaacgtacaagtatgtgaat
aagaaggaacaggagtctgaggtggacatgaagtccgcaactgacaatgcagctcggatt
ctgatgtggacagaactcatccgaggactgggcatgaccctaagttacctctttcgagag
cctgccaccatcaactacccctttgagaagggcccactgagtccgcgcttccgtggggag
catgcactgcgccgctacccatctggagaggagcgttgcattgcctgcaaactctgtgag
gccatctgtcctgcacaggccatcaccattgaggctgagccaagagccgatggcagccgc
cgaacgacacgctatgacatcgacatgaccaagtgtatctactgtggtttctgccaggaa
gcctgccctgttgatgccattgtggagggccccaacttcgagttctccaccgagacacac
gaggagttgctgtacaacaaggagaagctactcaacaatggagacaagtgggaggccgag
atcgctgccaacatccaggctgactacctgtaccggtga

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