KEGG   Mus musculus (house mouse): 230908
Entry
230908            CDS       T01002                                 
Symbol
Tardbp, 1190002A23Rik, TDP-43, Tdp43
Name
(RefSeq) TAR DNA binding protein
  KO
K23600  TAR DNA-binding protein 43
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03015  mRNA surveillance pathway
mmu05014  Amyotrophic lateral sclerosis
mmu05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    230908 (Tardbp)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    230908 (Tardbp)
   05022 Pathways of neurodegeneration - multiple diseases
    230908 (Tardbp)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    230908 (Tardbp)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Negative regulators of mRNA 3' end processing
     230908 (Tardbp)
SSDB
Motif
Pfam: TDP-43_C TDP43_N RRM_1 RRM_7 RRM_3 RL
Other DBs
NCBI-GeneID: 230908
NCBI-ProteinID: NP_663531
MGI: 2387629
Ensembl: ENSMUSG00000041459
UniProt: Q921F2 Q8BLD4 Q8R0B4 Q544R5
Structure
Position
4:complement(148696839..148711672)
AA seq 414 aa
MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI
LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDL
KDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNS
KQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVA
QSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLG
NNQGGNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQSQGSMQ
REPNQAFGSGNNSYSGSNSGAPLGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM
NT seq 1245 nt   +upstreamnt  +downstreamnt
atgtctgaatatattcgggtaacagaagatgagaacgatgaacccattgaaataccatca
gaagacgatgggacggtgttgctgtccacagttacagcccagtttccaggggcatgcggc
ctgcgctaccggaatcccgtgtctcagtgtatgagaggagtccgactggtggaaggaatt
ctgcatgccccagatgctggctggggcaatctggtatatgttgtcaactatcccaaagat
aacaaaaggaaaatggatgagacagatgcttcctctgcagtgaaagtgaaaagagcagtc
cagaaaacatctgacctcatagtgttgggtctcccctggaaaacaactgagcaggatctg
aaagactatttcagtacttttggagaggttcttatggttcaggtcaagaaagatcttaaa
actggtcactcgaaagggtttggctttgttcgatttacagaatatgaaacccaagtgaaa
gtaatgtcacaacgacatatgatagatgggcgatggtgtgactgtaaacttcccaactct
aagcaaagcccagacgagcctttgagaagcagaaaggtgtttgttggacgttgtacagag
gacatgactgctgaagagcttcagcagtttttctgtcagtatggagaagtggtagatgtc
ttcattcccaaaccattcagagcttttgccttcgtcacctttgcagatgataaggttgcc
cagtctctttgtggagaggatttgatcattaaaggaatcagcgtgcatatatccaatgct
gaacctaagcataatagcaatagacagttagaaagaagtggaagatttggtggtaatcca
ggtggctttgggaatcagggtgggtttggtaacagtagagggggtggagctggcttggga
aataaccagggtggtaatatgggtggagggatgaactttggtgcttttagcattaaccca
gcgatgatggctgcggctcaggcagcgttgcagagcagttggggtatgatgggcatgtta
gccagccagcagaaccagtcgggcccatctgggaataaccaaagccagggcagcatgcag
agggaaccaaatcaggcttttggttctggaaataattcctacagtggttctaattctggt
gccccccttggttgggggtcagcatcaaatgcaggatcgggcagtggttttaatgggggc
tttggctcgagcatggattctaagtcttctggctggggaatgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (11)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (106)   
   RefSeq(nuc) (10)   
   GenBank (48)   
   EMBL (48)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (147)   

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